para-Aminobenzoates

Benzoic acids, salts, or esters that contain an amino group attached to carbon number 4 of the benzene ring structure.

Also Known As:

4-Aminobenzoates; p-Aminobenzoates; 4 Aminobenzoate; 4 Aminobenzoates; p Aminobenzoate; p Aminobenzoates; para Aminobenzoate; para Aminobenzoates; 4-Aminobenzoate; p-Aminobenzoate; para-Aminobenzoate

Networked: 43 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        Aminobenzoates: 1
        para-Aminobenzoates: 43
        Metoclopramide: 2758
        Procaine: 1565
        Procainamide: 1129
        Cisapride: 696
        Aminosalicylic Acid: 479
        Tetracaine: 466
        4-Aminobenzoic Acid: 437
        Benzocaine: 331
        p-Aminohippuric Acid: 141
        RG7388: 70
        belnacasan: 67
        Acecainide: 49
        bentiromide: 49
        4-aminomethylbenzoic acid: 41
        leucinocaine mesylate: 27
        tanimilast: 23
        spearmint oil drug combinations iodoform eugenol butyl aminobenzoate: 17
        TM5441: 14
        5-chloro-2-(((2-(4-(diphenylmethyl)piperazin-1-yl)-2-oxoethoxy)acetyl)amino)benzoate: 12
        O(2)-(2,4-dinitro-5-(N-methyl-N-4-carboxyphenylamino)phenyl 1-N,N-dimethylamino)diazen-1-ium-1,2-diolate: 12
        Ethopabate: 9
        4-aminobenzoic acid-N-xyloside: 6
        cetaben: 6
        2,3-dihydroxypropyl 4-aminobenzoate: 5
        Acedoben: 5
        padimate-O: 5
        2-methoxy-4-amino-5-chlorobenzoic acid 2-(diethylamino)ethyl ester: 4
        aminaftone: 4
        disodium 4,4'-9((1,3-dioxo-1,3-propanediyl)diimino)dibenzoate: 4
        2-piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate: 3
        4-((N-Acetyl-L-tyrosyl)amino)benzoic acid: 3
        JY-1-106: 3
        padimate A: 3
        RO6839921: 3
        B 5354c: 2
        KLN 93: 2
        N-(4-acetamidobenzoyl)-L-glutamic acid: 2
        (4-(4,5-dihydro-1H-imidazol-2-yl)amino)benzoic acid: 1
        2-(3-hydroxypiperidino)ethyl 4-amino-5-chloro-2-methoxybenzoate: 1
        3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride: 1
        4-(dimethylamino)benzoic acid: 1
        4-(N-(1-(2-(4-cyanophenyl)ethyl)-4-hydroxypiperidin-4-ylmethyl)-N-methylamino)benzoic acid: 1
        4-aminobenzamide: 1
        BMS-962212: 1
        GGTI 2166: 1
        lipoyl-4-aminobenzoic acid: 1
        N-(1-carboxy-3-phenylpropyl)phenylalanine-4-aminobenzoate: 1
        octyl dimethyl 4-aminobenzoic acid: 1
        p-(butylamino)benzoic acid-2-(diethylamino)ethyl ester: 1
        PABA-ursodeoxycholic acid: 1
        padimate O drug combination avobenzone: 1
        propane-1,3-diyl bis(4-aminobenzoate): 1
        Propoxycaine: 1
        (1-butylpiperidin-4-yl)methyl 4-amino-3-methoxybenzoate
        (4-amino)phenylazobenzoic acid
        (4-aminomethyl)phenylazobenzoic acid
        (4-carboxyphenylamine)diamminechloroplatinum(I)
        1,3-bis(4-iminobenzoic acid)indane
        1-(4-((4-diethylamino-2-hydroxybenzylidene)amino)phenyl)ethanone
        2,3,5,6-tetrafluorophenyl N-(S-benzoylthioacetyl)glycylglycyl- p-aminobenzoate
        2-(3,5-dimethylpiperidino)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(4-((6-amino-1,3-dioxo-1H-benzo(de)isoquinolin-2(3H)-yl)methyl)piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(N-(2-pyrimidyl)piperazino)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(N-(phenyl)piperazino)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(p-aminobenzoyloxy)benzoic acid
        2-amino-4-picolinium 4-aminobenzoate
        3-(3,5-dibromo-4-hydroxyphenyl)-propylamino-acetamidobenzoic acid
        4-((3-(carboxymethylsulfanyl)-4-hydroxy-1-naphthyl)sulfamoyl)benzoic acid
        4-((5,6,7,8-tetrahydro-4-oxo-4H-(1)benzothieno(2,3-d)(1,3)thiazin-2-yl)amino)benzoic acid
        4-(2-(2-(4-chlorophenyl)-5,6-difluorobenzoimidazol-1-yl)-2-cyclohexylacetylamino)-3-fluorobenzoic acid
        4-(2-carboxypropylamino)-3-chlorobenzoic acid
        4-(2-carboxypropylamino)-3-hydroxybenzoic acid
        4-(2-carboxypropylamino)benzoic acid
        4-(3,3-dimethylbutyrylamino)-3,5-difluoro-N-thiazol-2-ylbenzamide
        4-(4-(N-ethyl-N-(3-(tert-butyloxycarbonyl)aminopropyl)amino)phenylazo)benzoic acid
        4-(5,6-dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido)benzoic acid
        4-(acetylamino)benzoic acid-1-(dimethylamino)-2-propanol
        4-(bis(2-((methylsulfonyl)oxy)ethyl)amino)-2-methylbenzoic acid
        4-(N-(6-(3,5-bis(decyloxy)phenoxy)hexyl)-N-(4-carboxyphenyl)amino)benzoic acid
        4-amino-3,5-dichlorobenzoic acid
        4-amino-3-chlorobenzoic acid
        4-amino-3-hydroxybenzoic acid
        4-aminobenzoic acid-N-mannoside
        4-methyl-3-bis(2-chloroethyl)aminobenzoic acid
        4-methylaminobenzoic acid
        4-N-bis(2-chloroethyl)aminobenzoic acid
        4-n-butylaminobenzoic acid
        4-nitroaniline 4-aminobenzoic acid
        B 5354a
        B 5354b
        BC-DXI01
        diethylhexylbutamido triazone
        disila-AM580
        ethyl 2-(4'-carboxybenzamido)-4-aminobenzoate
        ethyl 4-((3,5-di-tert-butyl-2-hydroxybenzylidene)amino)benzoate
        ethyl 4-diethylaminobenzoate
        ethyl 4-dimethylaminobenzoate
        ethyl 4-N,N-dimethylaminobenzoate
        HG-10-102-01
        isoamyl 4-N,N-dimethylaminobenzoate
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - Aminobenzoates: 1
        para-Aminobenzoates: 43
        Metoclopramide: 2758
        Procaine: 1565
        Procainamide: 1129
        Cisapride: 696
        Aminosalicylic Acid: 479
        Tetracaine: 466
        4-Aminobenzoic Acid: 437
        Benzocaine: 331
        p-Aminohippuric Acid: 141
        RG7388: 70
        belnacasan: 67
        Acecainide: 49
        bentiromide: 49
        4-aminomethylbenzoic acid: 41
        leucinocaine mesylate: 27
        tanimilast: 23
        spearmint oil drug combinations iodoform eugenol butyl aminobenzoate: 17
        TM5441: 14
        5-chloro-2-(((2-(4-(diphenylmethyl)piperazin-1-yl)-2-oxoethoxy)acetyl)amino)benzoate: 12
        O(2)-(2,4-dinitro-5-(N-methyl-N-4-carboxyphenylamino)phenyl 1-N,N-dimethylamino)diazen-1-ium-1,2-diolate: 12
        Ethopabate: 9
        4-aminobenzoic acid-N-xyloside: 6
        cetaben: 6
        2,3-dihydroxypropyl 4-aminobenzoate: 5
        Acedoben: 5
        padimate-O: 5
        2-methoxy-4-amino-5-chlorobenzoic acid 2-(diethylamino)ethyl ester: 4
        aminaftone: 4
        disodium 4,4'-9((1,3-dioxo-1,3-propanediyl)diimino)dibenzoate: 4
        2-piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate: 3
        4-((N-Acetyl-L-tyrosyl)amino)benzoic acid: 3
        JY-1-106: 3
        padimate A: 3
        RO6839921: 3
        B 5354c: 2
        KLN 93: 2
        N-(4-acetamidobenzoyl)-L-glutamic acid: 2
        (4-(4,5-dihydro-1H-imidazol-2-yl)amino)benzoic acid: 1
        2-(3-hydroxypiperidino)ethyl 4-amino-5-chloro-2-methoxybenzoate: 1
        3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride: 1
        4-(dimethylamino)benzoic acid: 1
        4-(N-(1-(2-(4-cyanophenyl)ethyl)-4-hydroxypiperidin-4-ylmethyl)-N-methylamino)benzoic acid: 1
        4-aminobenzamide: 1
        BMS-962212: 1
        GGTI 2166: 1
        lipoyl-4-aminobenzoic acid: 1
        N-(1-carboxy-3-phenylpropyl)phenylalanine-4-aminobenzoate: 1
        octyl dimethyl 4-aminobenzoic acid: 1
        p-(butylamino)benzoic acid-2-(diethylamino)ethyl ester: 1
        PABA-ursodeoxycholic acid: 1
        padimate O drug combination avobenzone: 1
        propane-1,3-diyl bis(4-aminobenzoate): 1
        Propoxycaine: 1
        (1-butylpiperidin-4-yl)methyl 4-amino-3-methoxybenzoate
        (4-amino)phenylazobenzoic acid
        (4-aminomethyl)phenylazobenzoic acid
        (4-carboxyphenylamine)diamminechloroplatinum(I)
        1,3-bis(4-iminobenzoic acid)indane
        1-(4-((4-diethylamino-2-hydroxybenzylidene)amino)phenyl)ethanone
        2,3,5,6-tetrafluorophenyl N-(S-benzoylthioacetyl)glycylglycyl- p-aminobenzoate
        2-(3,5-dimethylpiperidino)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(4-((6-amino-1,3-dioxo-1H-benzo(de)isoquinolin-2(3H)-yl)methyl)piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(N-(2-pyrimidyl)piperazino)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(N-(phenyl)piperazino)ethyl 4-amino-5-chloro-2-methoxybenzoate
        2-(p-aminobenzoyloxy)benzoic acid
        2-amino-4-picolinium 4-aminobenzoate
        3-(3,5-dibromo-4-hydroxyphenyl)-propylamino-acetamidobenzoic acid
        4-((3-(carboxymethylsulfanyl)-4-hydroxy-1-naphthyl)sulfamoyl)benzoic acid
        4-((5,6,7,8-tetrahydro-4-oxo-4H-(1)benzothieno(2,3-d)(1,3)thiazin-2-yl)amino)benzoic acid
        4-(2-(2-(4-chlorophenyl)-5,6-difluorobenzoimidazol-1-yl)-2-cyclohexylacetylamino)-3-fluorobenzoic acid
        4-(2-carboxypropylamino)-3-chlorobenzoic acid
        4-(2-carboxypropylamino)-3-hydroxybenzoic acid
        4-(2-carboxypropylamino)benzoic acid
        4-(3,3-dimethylbutyrylamino)-3,5-difluoro-N-thiazol-2-ylbenzamide
        4-(4-(N-ethyl-N-(3-(tert-butyloxycarbonyl)aminopropyl)amino)phenylazo)benzoic acid
        4-(5,6-dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido)benzoic acid
        4-(acetylamino)benzoic acid-1-(dimethylamino)-2-propanol
        4-(bis(2-((methylsulfonyl)oxy)ethyl)amino)-2-methylbenzoic acid
        4-(N-(6-(3,5-bis(decyloxy)phenoxy)hexyl)-N-(4-carboxyphenyl)amino)benzoic acid
        4-amino-3,5-dichlorobenzoic acid
        4-amino-3-chlorobenzoic acid
        4-amino-3-hydroxybenzoic acid
        4-aminobenzoic acid-N-mannoside
        4-methyl-3-bis(2-chloroethyl)aminobenzoic acid
        4-methylaminobenzoic acid
        4-N-bis(2-chloroethyl)aminobenzoic acid
        4-n-butylaminobenzoic acid
        4-nitroaniline 4-aminobenzoic acid
        B 5354a
        B 5354b
        BC-DXI01
        diethylhexylbutamido triazone
        disila-AM580
        ethyl 2-(4'-carboxybenzamido)-4-aminobenzoate
        ethyl 4-((3,5-di-tert-butyl-2-hydroxybenzylidene)amino)benzoate
        ethyl 4-diethylaminobenzoate
        ethyl 4-dimethylaminobenzoate
        ethyl 4-N,N-dimethylaminobenzoate
        HG-10-102-01
        isoamyl 4-N,N-dimethylaminobenzoate

Experts

1.	Ahn, Jiyoung: 2 articles (01/2016 - 09/2014)
2.	Goedert, James J: 2 articles (01/2016 - 09/2014)
3.	Hayes, Richard B: 2 articles (01/2016 - 09/2014)
4.	Sampson, Joshua N: 2 articles (01/2016 - 09/2014)
5.	Shi, Jianxin: 2 articles (01/2016 - 09/2014)
6.	Sinha, Rashmi: 2 articles (01/2016 - 09/2014)
7.	Xiong, Xiaoqin: 2 articles (01/2016 - 09/2014)
8.	Ke, Hangjun: 1 article (01/2019)
9.	Mather, Michael W: 1 article (01/2019)
10.	Al Attar, Layth: 1 article (05/2018)

Related Diseases

1.	Penile Induration (Peyronie's Disease) 05/01/2018 - "We present a case of Peyronie's disease treated with potassium para-aminobenzoate that developed acute liver injury. " 12/01/2008 - "Potassium para-aminobenzoate is an agent used in the treatment of sclerotic diseases including Peyronie's disease of the penis. " 01/01/1997 - "Potassium para-aminobenzoate for the treatment of Peyronie's disease: is it effective?" 07/23/1979 - "[Peyronie's disease treated with K-para-aminobenzoate and vitamin E]." 06/01/1959 - "Treatment of Peyronie's disease with potassium para-aminobenzoate (potaba)."
2.	Lichen Sclerosus et Atrophicus (Lichen Sclerosus) 01/01/1992 - "A comparison of morphoea and lichen sclerosus et atrophicus in vitro: the effects of para-aminobenzoate on skin fibroblasts." 06/01/1984 - "In five patients with symptomatic lichen sclerosus, significant clinical improvement was obtained following the administration of potassium para-aminobenzoate. " 01/01/1992 - "To study the effects of para-aminobenzoate on the dermis, fibroblast cell lines derived from lesions of lichen sclerosus et atrophicus, from morphoea and from normal skin were incubated with Potaba in vitro. " 06/01/1984 - "Treatment of lichen sclerosus with potassium para-aminobenzoate."
3.	Contact Dermatitis (Eczema, Contact) 12/01/2001 - "In this study in hairless mice, we compared two UVB absorbers, 2-ethylhexyl-p-methoxycinnamate (2-EHMC) and octyl-N-dimethyl-p-aminobenzoate (o-PABA), individually formulated in a common base lotion with a sunburn protection factor of 6. We measured their capacity to protect against suppression of the contact hypersensitivity (CHS) induced by three daily exposures of the dorsum to 6x the minimal erythemal/edematous dose (MED) of solar-simulated UV radiation (SSUV), in comparison with base lotion-treated mice exposed to 3 x 1 MED of SSUV. " 05/01/1992 - "This study compares the ability of two commonly used sunscreens--octyl dimethyl para-aminobenzoate (Padimate O) and 2-ethylhexyl-p-methoxycinnamate (2-EHMC)--to protect Langerhans cells (LC), Thy-1+ dendritic epidermal cells (Thy-1+ dEC), and local contact sensitivity (CS) from the effects of ultraviolet (UV) light. " 12/01/1994 - "A series of experimental sunscreen preparations based on a common vehicle, containing increasing concentrations of either octyl-N-dimethyl-p-aminobenzoate (o-PABA) or 2-ethylhexyl-p-methoxycinnamate (2-EHMC) as the ultraviolet B (UVB) absorber, has been tested in the hairless mouse for the ability to protect from erythema, from the systemically suppressive effects of UVB (280-320 nm) radiation on contact hypersensitivity, and from photoisomerization of epidermal urocanic acid. "
4.	Sunburn 07/01/1955 - "Cross sensitization from para-aminobenzoate in sunburn preventives." 12/01/2001 - "In this study in hairless mice, we compared two UVB absorbers, 2-ethylhexyl-p-methoxycinnamate (2-EHMC) and octyl-N-dimethyl-p-aminobenzoate (o-PABA), individually formulated in a common base lotion with a sunburn protection factor of 6. We measured their capacity to protect against suppression of the contact hypersensitivity (CHS) induced by three daily exposures of the dorsum to 6x the minimal erythemal/edematous dose (MED) of solar-simulated UV radiation (SSUV), in comparison with base lotion-treated mice exposed to 3 x 1 MED of SSUV. "
5.	Pain (Aches) 01/01/2007 - "Placebo-controlled studies examining these agents have failed to show a consistent beneficial effect on Peyronie's disease, with the exception of para-aminobenzoate, which may decrease plaque size and curvature, and acetyl-L-carnitine, which may reduce erectile pain and inhibit disease progression. " 01/01/1997 - "Potassium para-aminobenzoate (POTABA) has long been suggested as a treatment for the plaque, curvature, and pain produced by chronic Peyronie's disease. "

Related Drugs and Biologics

1.	Potassium
2.	Phosphodiesterase 5 Inhibitors
3.	Tamoxifen
4.	Carnitine (L-Carnitine)
5.	4-Aminobenzoic Acid (4 Aminobenzoic Acid)
6.	octylmethoxycinnamate (octyl-methoxycinnamate)
7.	Sunscreening Agents (Sunscreens)
8.	Metalloendopeptidases (Metalloendopeptidase)
9.	Acetylcarnitine (Alcar)
10.	Dissolved Organic Matter

Related Therapies and Procedures

1.	Therapeutics