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3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride

structure given in first source; a 5-HT(4) receptor antagonist

Also Known As:

RS 23597-190; RS-23597-190

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - 3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        Aminobenzoates: 1
        para-Aminobenzoates: 43
        3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride: 1
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - Aminobenzoates: 1
        para-Aminobenzoates: 43
        3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride: 1

Related Diseases

1.

Tachycardia (Tachyarrhythmias)

09/01/1993 - "Intravenous infusion of RS 23597-190 in the conscious, restrained rat antagonized the von Bezold Jarisch reflex induced by 2-methyl 5-HT, with an ID50 of 300 microg kg-1 min-1, i.v. In the anaesthetized,bilaterally vagotomized micropig, RS 23597-190 (6 mg kg-1, i.v.) antagonized 5-HT-induced tachycardia with a half-life of 77 (63-99) min. Transient arrhythmic effects were noted after administration of the compound.7. In conclusion, RS 23597-190 acts as a high affinity, selective competitive antagonist at 5-HT4 receptors. "

Related Drugs and Biologics

1.	Serotonin (5 Hydroxytryptamine)

Related Therapies and Procedures

1.	Intravenous Infusions