Gingival Recession

Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).

Also Known As:

Networked: 718 relevant articles (36 outcomes, 151 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Dentin Sensitivity
2.	Chronic Periodontitis
3.	Aggressive Periodontitis (Periodontosis)
4.	Calculi (Calculus)
5.	Gingival Recession

Experts

1.	Sculean, Anton: 23 articles (06/2015 - 01/2003)
2.	Zucchelli, Giovanni: 11 articles (06/2015 - 05/2002)
3.	Casati, Marcio Zaffalon: 10 articles (01/2016 - 04/2008)
4.	Santamaria, Mauro Pedrine: 10 articles (08/2015 - 06/2007)
5.	Schwarz, Frank: 10 articles (05/2015 - 01/2003)
6.	Sallum, Enilson Antônio: 10 articles (09/2013 - 06/2007)
7.	Chambrone, Leandro: 9 articles (02/2015 - 09/2003)
8.	Nociti, Francisco Humberto: 9 articles (09/2013 - 06/2007)
9.	Gera, István: 9 articles (07/2013 - 03/2007)
10.	Becker, Jürgen: 9 articles (09/2008 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Gingival Recession:

1.	platelet-derived growth factor BB (becaplermin)FDA Link 03/01/2014 - "The combination of rhPDGF-BB and β-TCP represented a therapeutic combination that was effective in treating multiple gingival recession defects. " 05/01/2014 - "In this prospective consecutive case series, recombinant human platelet-derived growth factor-BB (rhPDGF-BB) was combined with CTGs for the treatment of Miller Class I or II mandibular gingival recession defects in 11 healthy patients. " 01/01/2013 - "In this prospective consecutive case series, recombinant human platelet-derived growth factor BB (rhPDGF-BB) was combined with CTGs for the treatment of Miller Class I or II gingival recession defects. " 11/01/2011 - "Minimally invasive treatment of maxillary anterior gingival recession defects by vestibular incision subperiosteal tunnel access and platelet-derived growth factor BB." 03/01/2014 - "A comparative evaluation of rhPDGF-BB + β-TCP and subepithelial connective tissue graft for the treatment of multiple gingival recession defects in humans."
2.	CollagenIBA 10/01/2013 - "Efficacy of collagen membrane seeded with autologous gingival fibroblasts in gingival recession treatment: a randomized, controlled pilot study." 03/01/2012 - "The aim of the present study is to evaluate the use of a porcine collagen matrix (PCM) plus CAF as an alternative to CTG+CAF for the treatment of gingival recessions (REC), in a prospective randomized, controlled clinical trial. " 07/01/2009 - "Within the limits of this study we concluded that the treatment of gingival recession defects with GTR, associating collagen membrane with DFDBA, showed better outcomes in terms of a larger extension of neoformed cementum and bone, as well as in terms of a smaller proportion of residual recessions." 07/01/2009 - "Treatment of gingival recession with collagen membrane and DFDBA: a histometric study in dogs." 01/01/2009 - "The aim of this study was to assess the effectiveness of using a GTR resorbable collagen membrane in conjunction with coronally advanced flap (CAF) as compared to CAF alone in the treatment of Miller's Class I & II gingival recessions. "
3.	FibrinIBA 04/01/2015 - "The aim of this study was to compare the clinical efficacy of coronally advanced flap (CAF) alone and in combination with autologous platelet rich fibrin membrane (PRF) in Miller's class I and II gingival recessions. " 11/01/2014 - "The aim of this study is to evaluate the clinical efficacy of platelet-rich fibrin (PRF) in combination with coronally advanced flap (CAF) in the treatment of localized gingival recessions. " 04/01/2015 - "Clinical evaluation and comparison of the efficacy of coronally advanced flap alone and in combination with platelet rich fibrin membrane in the treatment of Miller Class I and II gingival recessions." 01/01/2015 - "Clinical evaluation of autologous platelet-rich fibrin in the treatment of multiple adjacent gingival recession defects: a 12-month study." 01/01/2015 - "The aim of this study was to determine whether the addition of an autologous platelet rich fibrin (PRF) membrane to a coronally advanced flap (CAF) would improve the clinical outcome in terms of root coverage, in the treatment of isolated gingival recession. "
4.	beta-tricalcium phosphateIBA 01/01/2013 - "The aim of this study was to investigate the effect of beta-tricalcium phosphate (β-TCP) particles in combination with acellular dermal matrix (ADM) allograft in gingival recession. " 01/01/2013 - "Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium phosphate." 04/01/2009 - "CTG and rhPDGF-BB + beta-TCP + wound-healing dressing are effective treatment modalities for clinically correcting gingival recession defects. " 02/01/2009 - "Gingival recession defects were surgically created in six premolar teeth with no more than 3 mm of keratinized marginal tissue, an osseous crest 2 to 3 mm apical to the newly created gingival margin, and recession depth of at least 3 mm. The defects were left untouched for 2 months; then, four defects were grafted with rhPDGF-BB + beta-TCP + a wound healing dressing, and two defects received CTGs. " 12/01/2005 - "Treatment with rhPDGF-BB stimulated a significant increase in the rate of CAL gain, reduced gingival recession at 3 months post-surgery, and improved bone fill as compared to a beta-TCP bone substitute at 6 months."
5.	Collagen Type I (Type I Collagen)IBA 10/01/2014 - "In the CAF + Type I collagen membrane (NEOMEM)-treated (Group B) sites the baseline gingival recession was 2.34 ± 0.48 mm, while in the CAFtreated (Group A) sites it was 2.52 ± 0.84 mm. Both the treatments resulted in significant recession depth reduction (P < 0.001), but the reduction was significantly greater (P < 0.01) for Group B than Group A. " 07/01/2014 - "The present study evaluates the efficacy of bioresorbable 100% type I collagen membrane of bovine origin in the treatment of human gingival recession. " 07/01/2014 - "Evaluation of the efficacy of 100% Type-I collagen membrane of bovine origin in the treatment of human gingival recession: A clinical study." 10/01/2014 - "The aim of this study is to compare and evaluate the clinical outcome of the envelope-type of coronally advanced flap (CAF) alone versus envelope type of coronally advanced flap plus type I collagen membrane (NEOMEM) in the treatment of multiple buccal gingival recessions, using the split mouth study. " 10/01/2014 - "Comparative evaluation of envelope type of advanced flap with and without type I collagen membrane (NEOMEM™) in the treatment of multiple buccal gingival recession defects: A clinical study."
6.	PlasticsIBA 04/01/2012 - "Smoking may negatively affect the results achieved through periodontal plastic procedures; however, the association of ADMG and EMD is beneficial in the root coverage of gingival recessions in smokers, 6 months after the surgery." 04/01/2014 - "To systematically review the efficacy of periodontal plastic procedures (PPP) in the treatment of multiple gingival recessions (MGR). " 04/01/2014 - "Efficacy of periodontal plastic procedures in the treatment of multiple gingival recessions." 05/01/2013 - "Various periodontal plastic procedures are available for treatment of localized gingival recessions. " 01/01/2013 - "Periodontal plastic microsurgery in the treatment of deep gingival recession after orthodontic movement."
7.	Polytetrafluoroethylene (Teflon)FDA Link 04/01/1996 - "Adjacent gingival recession treated with expanded polytetrafluoroethylene membranes: a report of 2 cases." 01/01/1995 - "Healing response of human buccal gingival recessions treated with expanded polytetrafluoroethylene membranes. " 11/01/1993 - "The use of expanded polytetrafluoroethylene (ePTFE) membranes in the treatment of mucogingival problems such as gingival recession, has been recently described. " 06/01/2011 - "The aim of this study was to clarify the adjunctive effect of enamel matrix derivative (EMD) on expanded polytetrafluoroethylene membrane guided tissue regeneration (GTR)-based root coverage by creating gingival recessions in beagle dogs. " 04/01/1996 - "We report two cases illustrating treatment for adjacent facial gingival recession using guided tissue regeneration (GTR) with expanded polytetrafluoroethylene membranes. "
8.	ToothpastesIBA 01/01/2011 - "The findings suggested that dietary acid, gingival recession and erosion were significantly associated with DH, while desensitising toothpastes was the key management strategy used for DH in this patient population." 01/01/2011 - "Gingival recession and erosion emerged as significant pre-disposing factors, whereas using desensitising toothpastes was the most important management strategy. " 10/01/2010 - "Within the limitations of the present study, a significant effect of combined desensitizer toothpaste and diode laser therapy occurs in the treatment of desensitization of teeth with gingival recession. " 01/01/2013 - "Additionally, toothbrushing with toothpaste is implicated in 'healthy' gingival recession. " 10/01/2010 - "The purpose of this study was to evaluate and compare clinically the efficacy of desensitizer toothpaste alone and in combination with the diode laser in the management of dentin hypersensitivity (DH), as well as both the immediate and late therapeutic effects on teeth with gingival recessions. "
9.	Tuberculin (PPD)IBA 08/01/2015 - "Clinical recordings included the following: probing pocket depth (PPD), gingival recession (RE), clinical attachment level (CAL), Gingival and Plaque Index. " 10/01/2014 - "Following clinical and radiographic parameters were recorded at baseline, 3 months and 6 months post operatively: 1) Probing pocket depth (PPD); 2)Clinical attachment level (CAL); 3) Gingival recession (GR); 4) Radiographic Defect Depth. " 06/01/2014 - "Plaque index and gingival index (GI) were recorded at baseline, 6 weeks, 3 months, 6 months and 9 months, whereas probing pocket depth (PPD), clinical attachment level and gingival recession (GR) were recorded at baseline, 6 and 9 months postoperatively. " 04/01/2014 - "Clinical probing depth (PPD), clinical attachment level (CAL), clinical gingival recession level (REC), plaque index (PI) score, and sulcus blooding index (SBI) score were recorded at the time of surgery, and at the 3rd and 6th months after operation. " 02/01/2014 - "Clinical attachment level (CAL) as the primary outcome variable, calculated as the sum of probing pocket depth (PPD) and gingival recession, and radiological alveolar bone level were recorded at baseline, 6 months and 5 years. "
10.	enamel matrix proteinsIBA 04/01/2012 - "This clinical study compared the results obtained by treating gingival recession using enamel matrix derivative (Emdogain gel(®)) along with coronally positioned flap and coronally positioned flap alone. " 05/01/2007 - "Enamel matrix derivative Emdogain as an adjuvant for a laterally-positioned flap in the treatment of gingival recession: an electron microscopic appraisal." 05/01/2007 - "Treatment of gingival recession using enamel matrix proteins: a case report with 4-year follow-up." 12/01/2003 - "This article describes the clinical procedure and outcome of surgical treatment of gingival recessions with the adjunctive use of Emdogain gel, an enamel matrix derivative bioactive material for periodontal reconstructive surgery. " 12/01/2003 - "Surgical treatment of gingival recessions using emdogain gel: clinical procedure and case reports."

Therapies and Procedures

1.	Transplants (Transplant) 11/01/2002 - "The CT and ADM subepithelial grafts were similarly able to successfully treat gingival recession defects; however, the CT group obtained a significantly greater increase in KT, and showed a quicker complete healing." 10/01/1994 - "Root defects with wide or deep-wide gingival recessions can be successfully treated with a subepithelial connective tissue graft. " 11/01/2013 - "The objective of this study was to clinically evaluate and compare the efficacy of platelet concentrate graft (PCG) with that of subepithelial connective tissue graft (SCTG) using a coronally advanced flap technique in the treatment of gingival recession. " 05/01/2015 - "The aim of the present study was to assess the efficacy of acellular dermal matrix (ADM) and subepithelial connective tissue grafts (sCTG) in the treatment of Miller class I and II gingival recession (GR) defects. " 09/01/2013 - "The aim of this randomized clinical study was to compare the efficacy of EMD with a connective tissue graft (CTG) for the treatment of adjacent Miller Class l and II multiple gingival recessions. "
2.	Guided Tissue Regeneration 10/01/2008 - "[Therapeutic efficacy of guided tissue regeneration and connective tissue autotransplants with periosteum in the management of gingival recession]." 07/01/2002 - "Guided tissue regeneration (GTR)-based root coverage has been utilized to correct gingival recession defects with promising results. " 08/01/1997 - "The use of guided tissue regeneration (GTR) procedures in the treatment of gingival recession has shown promising results and is gaining clinical acceptance. " 10/01/2008 - "The aim of this study was to verify efficacy of surgical procedures that include connective tissue autotransplants with periosteum and guided tissue regeneration for the treatment of gingival recession. " 01/01/2005 - "The aim of the present study was to evaluate the changes of the mucogingival complex of guided tissue regeneration (GTR)-treated gingival recession defects over a 10-year follow-up. "
3.	Aftercare (After-Treatment) 05/01/2005 - "After treatment, fewer than 10% of subjects had gingival recession greater than 2 mm, and, at follow-up, 5% of the pre-existing gingival recession had improved. " 02/01/2015 - "Gingival recession after treatment with EMD and GTR showed a tendency toward positive results, whereas no such tendency was observed for OFD. " 09/01/2015 - "The aim of the present study is to evaluate the association of patient-related and site-specific factors, as well as the adopted treatment modality, with the change in buccal (bREC) and interdental (iREC) gingival recession observed at 6 months after treatment of periodontal intraosseous defects with the single flap approach (SFA). " 08/01/2010 - "Further randomized clinical studies including clinical examination of hygiene and gingival condition before, during and after treatment are needed to clarify the effect of orthodontic changes in incisor inclination and the occurrence of gingival recession." 10/01/2007 - "Each study provided mean clinical attachment level, keratinized tissue, probing pocket depth, gingival recession depth and root coverage percentage before and after treatment with coronally positioned flap alone, coronally positioned flap+chemical root surface conditioning, or coronally positioned flap+EMD. "
4.	Homologous Transplantation (Allograft) 09/01/2015 - "Comparative evaluation of the effectiveness of acellular dermal matrix allograft and subepithelial connective tissue to coronally advanced flap alone in the treatment of multiple gingival recessions: A clinical study." 09/01/2015 - "However, chorion membrane has been used in combination with amnion membrane no study has compared these allograft membranes in the treatment of gingival recession. " 09/01/2015 - "Amnion and Chorion Allografts in Combination with Coronally Advanced Flap in the Treatment of Gingival Recession: A Clinical Study." 06/01/2009 - "To study the wound healing of acellular dermal matrix (ADM) allografts when used together with coronally advanced flaps (CAF) in the treatment of localized gingival recessions in the mini-pig experimental model. " 10/01/2008 - "The first and second studies highlight the allograft's performance in the treatment of gingival recession. "
5.	Lasers (Laser) 01/01/2014 - "Based on overall improvement in parameters such as superiority of laser applicationin some indices, lack of thermal damage and gingival recession with the specific settings usedin this study, the application of laser as an adjunctive treatment together with common methodsis preferable." 01/01/2015 - "A total of 15 patients who required treatment for gingival recessions were selected from the University of Genoa Laser and Restorative Dentistry Department. " 03/01/2010 - "Four weeks after laser CSF, the sulcus depth increased by 0.67 mm, but no gingival recession was observed. " 10/01/2012 - "The closed approach therapies: SRP, laser-curettage/SRP, and laser-curettage/SRP/laser-sealing resulted in less gingival recession than the open approach (papilla reflection/flap closure). " 12/01/2009 - "The aim of this study was to evaluate the effectiveness of two types of lasers, the Nd:YAG laser and the 685-nm diode laser, as dentin desensitizers as well as both the immediate and late therapeutic effects on teeth with gingival recession. "