Mass Drug Administration

Administration of a medication to at-risk individuals in a population without individual diagnosis. It is often used in order to treat, control, and/or prevent spread of often endemic DISEASE OUTBREAKS such as NEGLECTED DISEASES in high disease burden areas.

Also Known As:

Networked: 1657 relevant articles (87 outcomes, 192 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Weil, Gary J: 56 articles (07/2022 - 02/2004)
2.	Solomon, Anthony W: 30 articles (03/2022 - 01/2009)
3.	Anderson, Roy M: 26 articles (01/2022 - 03/2015)
4.	Fischer, Peter U: 25 articles (07/2022 - 09/2011)
5.	Bockarie, Moses J: 25 articles (04/2018 - 02/2003)
6.	West, Sheila K: 24 articles (10/2022 - 11/2010)
7.	Romani, Lucia: 23 articles (09/2022 - 06/2014)
8.	Steer, Andrew C: 23 articles (09/2022 - 04/2013)
9.	Marks, Michael: 23 articles (01/2022 - 09/2014)
10.	von Seidlein, Lorenz: 23 articles (11/2021 - 03/2003)

Related Diseases

1.	Malaria 01/01/2022 - "Instead, the focus should be on reducing the malaria burden more rapidly in the remaining localised high transmission foci with proven effective interventions, including mass drug administration. " 01/01/2020 - "A mass drug administration trial was carried out in Southern Province, Zambia, between 2014 and 2016, in conjunction with a standard of care package that included improved surveillance, increased access to malaria case management, and sustained high levels of vector control coverage. " 12/13/2019 - "Malaria resurgence after significant reduction by mass drug administration on Ngodhe Island, Kenya." 11/04/2000 - "Malaria can be eliminated on isolated islands with well-adapted short-term mass drug administration and sustained vector control if there is a high degree of community participation." 11/01/2023 - "Improved surveillance, better access to effective treatment, more labour-efficient vector control, continued drug development, targeted mass drug administration, and sustained political commitment are required to achieve targets for malaria reduction by the end of this decade."
2.	Filarial Elephantiasis (Lymphatic Filariasis) 08/01/2014 - "Mass drug administration (MDA) programs have dramatically reduced lymphatic filariasis (LF) incidence in many areas around the globe, including American Samoa. " 04/01/2012 - "A rapid antibody detection test is very useful for the detection of lymphatic filariasis, especially for certification and surveillance of post-mass drug administration. " 08/16/2006 - "Vector control successfully eliminated lymphatic filariasis when implemented alone or with mass drug administration. " 01/01/2023 - "The efficacy of MOX for the treatment of lymphatic filariasis (LF) and its potential use in mass drug administration protocols for the elimination of LF is currently under evaluation. " 01/01/2021 - "Larger studies should be performed to further assess the safety and efficacy of IDA as a mass drug administration regimen to eliminate brugian filariasis. "
3.	Infections 10/01/2023 - "The Geshiyaro project aims to assess the feasibility of interrupting transmission of soil-transmitted helminths (STH) and schistosome (SCH) infection in the Wolaita zone of southern Ethiopia through high coverage community-wide mass drug administration (MDA), in combination with improved water, sanitation, and hygiene services and behaviour change communication delivered through the existing health care infrastructure. " 04/30/2023 - "Mass drug administration (MDA) programs led to a significant reduction in the number of infected individuals, but the consequences of the treatment and clearance of infection in regard to host immunity remain uncertain. " 04/15/2020 - "Mass Drug Administration (MDA) holds some promise in the rapid reduction of Plasmodium falciparum infections, but requires considerable investment of resources and time to mobilize the target communities. " 03/09/2016 - "Simulation results indicate a high proportion of low-density infections were missed by rapid diagnostic tests that would be treated and cleared with mass drug administration (MDA). " 12/01/2014 - "It is generally recommended to perform multiple stool examinations in order to improve the diagnostic accuracy when assessing the impact of mass drug administration programmes to control human intestinal worm infections and determining efficacy of the drugs administered. "
4.	Schistosomiasis (Bilharziasis) 01/01/2020 - "Through its Rapid Answers Project (RAP), the SCORE conducted seven systematic reviews, including four associated meta-analyses, on issues related to screening for schistosomiasis, enhancing mass drug administration, treatment impacts, and the efficacy of snail control for prevention of human schistosomiasis. " 10/01/2015 - "With the support of Good Neighbors International in collaboration with National Institute of Medical Research, Mwanza, Tanzania, integrated control applying mass drug administration (MDA), health education using PHAST, and improved safe water supply has been implemented on Kome Island over 5 years for controlling schistosomiasis and soil-transmitted helminths (STHs). " 08/20/2013 - "While schistosomiasis has been eradicated from Japan and significantly reduced in parts of China and Egypt, transmission in many other regions remains ongoing due to the wide-spread distribution of the intermediate snail host, poor sanitation, lack of health education and decreasing compliance to mass drug administration. " 09/01/2022 - "Termed a public health problem, NALA, an international public health non-governmental organization, and their partners implemented a novel model of intervention, which aimed to compliment mass drug administration (MDA) campaigns with behavioral change (BC) and improved sanitation to achieve sustained elimination of schistosomiasis. " 12/01/2021 - "What is the impact of acquired immunity on the transmission of schistosomiasis and the efficacy of current and planned mass drug administration programmes?"
5.	Onchocerciasis 01/01/2016 - "In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. " 11/07/2023 - "The objective of this study was to assess the situation of onchocerciasis transmission in the Cascades region, nine years after the resumption of mass drug administration. " 11/14/2023 - "Awareness of and participation in mass drug administration programs used for onchocerciasis control in the Atwima Nwabiagya North District, Ghana." 07/01/2023 - "Enhancing onchocerciasis elimination program management: A biological approach to deciding when to begin Stop Mass Drug Administration activities." 07/01/2023 - "Correction: Onchocerciasis: Target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions."

Related Drugs and Biologics

1.	Ivermectin (Mectizan)
2.	Albendazole (Albenza)
3.	Diethylcarbamazine (Hetrazan)
4.	Praziquantel (Biltricide)
5.	piperaquine
6.	Vaccines
7.	Azithromycin (Zithromax)
8.	artenimol (dihydroartemisinin)
9.	Antigens
10.	artemisinin (artemisinine)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Mass Drug Administration
3.	Chemoprevention
4.	Insecticide-Treated Bednets
5.	Combination Drug Therapy (Combination Chemotherapy)