Vaccines

Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa, or rickettsiae), antigenic proteins derived from them, or synthetic constructs, administered for the prevention, amelioration, or treatment of infectious and other diseases.

Networked: 23992 relevant articles (2748 outcomes, 2891 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hill, Adrian V S: 62 articles (01/2016 - 10/2003)
2.	Centers for Disease Control and Prevention (CDC): 56 articles (06/2015 - 12/2000)
3.	Rappuoli, Rino: 49 articles (01/2016 - 01/2002)
4.	Poland, Gregory A: 48 articles (11/2015 - 05/2003)
5.	Gilbert, Sarah C: 40 articles (01/2016 - 01/2005)
6.	Schlom, Jeffrey: 37 articles (11/2015 - 01/2002)
7.	Gulley, James L: 33 articles (11/2015 - 08/2003)
8.	Aaby, Peter: 30 articles (05/2015 - 01/2002)
9.	Subbarao, Kanta: 29 articles (01/2015 - 11/2002)
10.	Esposito, Susanna: 28 articles (11/2015 - 02/2004)

Related Diseases

1.	Infection 04/18/2013 - "Nevertheless, natural immunity against CMV provides some protection against infection and disease, natural history studies have defined the serological and molecular biological techniques needed for endpoints in future clinical trials of vaccines and CMV is not highly communicable, suggesting that it may not be necessary to achieve very high levels of population immunity through vaccination in order to affect transmission. " 06/01/2011 - "By taking into account the leading role of specific cellular immunity in the development of protection against the majority of dangerous and extremely dangerous infections of bacterial, viral, and rickettsial nature, the study of the above immunity should be considered as most important on estimating the body's immunological rearrangement when vaccines against respective infections are administered. " 09/01/2006 - "Preventive vaccines against HPVs 16 and 18 have been developed, and in phase III clinical trials they have demonstrated 100% efficacy for prevention of persistent infection and high risk cervical squamous intraepithelial neoplasias positive for these HPV types, suggesting that these vaccines, if made widely available, will dramatically reduce the burden of CC." 02/01/2004 - "With the use of a virtually identical study design, vaccines against Hib were shown to be highly effective in preventing invasive Hib infections but were not effective in preventing invasive infections due to S. " 01/01/2015 - "Subcutaneous vaccination with the GP-based vaccines provided significant protection against subsequent pulmonary infection with highly virulent strains of C. neoformans and C. gattii. "
2.	Neoplasms (Cancer) 05/01/2001 - "Initial clinical trials with the HPV types which are most prevalent in cervical cancer exhibited promising results, yet next generation vaccines are already under development." 01/01/2015 - "A combined HPV-16/18 prevalence of 69.9% in ICC specimens suggests that current vaccines will be highly protective against cervical cancer in Zambia." 01/01/2014 - "Current protective virus-like particle and capsid-based vaccines are highly protective against vaccine-matched HPV types, and continued improvements in second-generation vaccines will lead to broader protection and cross-protection against the cancer-associated types. " 02/01/2012 - "While the development of anti-HPV prophylactic vaccines represents one of the most remarkable triumphs of modern medicine, there is much more to be done in terms of advancing safe and effective treatments for cervical and head-and-neck cancers. " 01/01/2012 - "Vaccines giving best protection against solid tumor growth corresponded to the archaeosome adjuvant composition that gave highest immune activity in immunized mice."
3.	Human Influenza (Influenza) 01/02/2015 - "To the best of our knowledge, this study is the first report describing the immunological profile of the NP-containing VLPs vaccines in mice and chicken models, and the results demonstrate that the non-infectious, genome less VLPs, particularly those containing NP, represent a promising strategy for the development of a safe and effective vaccine to control pandemic influenza." 08/26/2015 - "Improved understanding of the degree of influenza seasonality in tropical countries of the world should allow for the strengthening of national vaccination policies and use of the most appropriate available vaccines. " 01/01/2013 - "Moreover vaccination with these vaccines induced full protection against lethal challenges with homologous and highly drifted influenza strains. " 02/01/2012 - "Current strategies involve post-emergent homotypic vaccines that are modelled upon select circulating 'seasonal' influenzas, but cannot induce cross-strain protection against newly evolved or zoonotically introduced highly pathogenic influenza (HPI). " 09/09/2011 - "The identification of immune correlates of protection against highly pathogenic human-adapted influenza is instrumental in the development of the next generation of vaccines. "
4.	Whooping Cough (Pertussis) 09/22/2015 - "Several observational studies provide evidence that acellular pertussis vaccines (aP) are less protective against pertussis disease than highly effective whole-cell pertussis vaccines (wP), however, concerns have been raised that some of these findings may be confounded by age. " 01/01/1997 - "Vaccine efficacy of the most efficacious acellular pertussis vaccines in the three recent placebo-controlled clinical trials, when estimated using the primary clinical case criterion, does not change substantially with the inclusion of serological confirmation in addition to culture confirmation. " 01/01/2015 - "Booster vaccination for teenagers and development of highly efficacious pertussis vaccines are needed." 10/01/2014 - "First generation whole-cell (wP) and second generation acellular (aP) pertussis vaccines have been highly effective in preventing childhood deaths due to pertussis, yet both vaccines have drawbacks that have limited their long-term usefulness. " 09/01/2014 - "The intensive use of pertussis vaccines has dramatically reduced the incidence of whooping cough during the 20th century. "
5.	Communicable Diseases (Infectious Diseases) 12/05/2014 - "Vaccination is the most effective means of preventing infectious diseases; however, few vaccines are effective against Streptococcus iniae (S. " 05/23/2014 - "Vaccines represent one of the most compelling examples of how biomedical research has improved society by saving lives and dramatically reducing the burden of infectious disease. " 11/01/2013 - "Vaccines elicit immune responses, provide protection against microorganisms and are considered as one of the most successful medical interventions against infectious diseases. " 10/01/2013 - "During the 20th century, deaths from a range of serious infectious diseases decreased dramatically due to the development of safe and effective vaccines. " 11/01/2008 - "There has been a remarkable progress in the prevention,control and even eradication of infectious diseases with improved hygiene and development of antimicrobials and vaccines. "

Related Drugs and Biologics

1.	Antigens
2.	Antibodies
3.	DNA (Deoxyribonucleic Acid)
4.	Proteins (Proteins, Gene)
5.	Influenza Vaccines (FluMist)
6.	DNA Vaccines
7.	Epitopes
8.	Antiviral Agents (Antivirals)
9.	Peptides
10.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Immunotherapy
2.	Drug Therapy (Chemotherapy)
3.	Therapeutics
4.	Transplantation (Transplant Recipients)
5.	Injections