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coagulin-L

an anti-hyperglycemic agent that inhibits adipogenesis; isolated from Withania coagulans; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chauhan, Parul: 2 articles (10/2016 - 03/2014)
2.	Saini, Deepika: 2 articles (10/2016 - 03/2014)
3.	Barthwal, Manoj Kumar: 1 article (10/2016)
4.	Maurya, Preeti: 1 article (10/2016)
5.	Reddy, Sukka Santosh: 1 article (10/2016)
6.	Yadav, Prem Prakash: 1 article (10/2016)
7.	Beg, Muheeb: 1 article (03/2014)
8.	Gaikwad, Anil Nilkanth: 1 article (03/2014)
9.	Rajan, Sujith: 1 article (03/2014)
10.	Shankar, Kripa: 1 article (03/2014)

Related Diseases

1.	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/15/2014 - "Taken together all evidences, a known anti-hyperglycemic agent coagulin-L has shown potential to inhibit adipogenesis significantly, which can be therapeutically exploited for treatment of obesity and metabolic syndrome. "
2.	Endotoxemia 10/15/2016 - "Furthermore, coagulin-L (10, 25, 50mg/kg, p.o.), undermined the LPS (10mg/kg, i.p.) induced endotoxemia response in mice as evinced from diminished cytokine release, nitric oxide, aortic p38 MAPK activation and endothelial tissue impairment besides suppressing NOX2 and NOX4 expression in liver and aorta. "
3.	Peritonitis 10/15/2016 - "To extend, coagulin-L also suppressed carrageenan-induced paw edema and thioglycollate-induced peritonitis in mice. "
4.	Obesity 03/15/2014 - "Taken together all evidences, a known anti-hyperglycemic agent coagulin-L has shown potential to inhibit adipogenesis significantly, which can be therapeutically exploited for treatment of obesity and metabolic syndrome. "
5.	Edema (Dropsy) 10/15/2016 - "To extend, coagulin-L also suppressed carrageenan-induced paw edema and thioglycollate-induced peritonitis in mice. "

Related Drugs and Biologics

1.	p38 Mitogen-Activated Protein Kinases
2.	Cytokines
3.	Nitric Oxide (Nitrogen Monoxide)
4.	Carrageenan