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HDL Cholesterol

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Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.

Also Known As:

Cholesterol, HDL; Cholesterol, HDL2; Cholesterol, HDL3; HDL(2) Cholesterol; HDL(3) Cholesterol; HDL2 Cholesterol; HDL3 Cholesterol; alpha-Lipoprotein Cholesterol; Cholesterol, alpha-Lipoprotein; alpha Lipoprotein Cholesterol; High Density Lipoprotein Cholesterol

Networked: 12168 relevant articles (329 outcomes, 1103 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Kastelein, John J P: 56 articles (07/2015 - 05/2002)
2.	Ballantyne, Christie M: 47 articles (01/2015 - 11/2002)
3.	Rader, Daniel J: 44 articles (10/2015 - 05/2002)
4.	D'Agostino, Ralph B: 41 articles (10/2015 - 10/2002)
5.	Vasan, Ramachandran S: 33 articles (10/2015 - 03/2003)
6.	Schaefer, Ernst J: 33 articles (05/2015 - 02/2002)
7.	Després, Jean-Pierre: 30 articles (07/2014 - 01/2003)
8.	Srinivasan, Sathanur R: 30 articles (01/2014 - 09/2002)
9.	Berenson, Gerald S: 29 articles (01/2014 - 09/2002)
10.	Hofman, Albert: 26 articles (01/2016 - 09/2003)

Related Diseases

1.	Body Weight (Weight, Body) 08/01/2013 - "A statistically significant improvement in lipid parameters (except HDL cholesterol) was observed while body weight changed minimally. " 02/15/2016 - "In this study, maternal separation during lactation reduced body weight gain in the female adult offspring without affecting food intake, and altered total and HDL-cholesterol levels. " 01/01/2014 - "At the same time, short-term studies have demonstrated a positive relationship of nutrition with reduction in body weight, as well as favourable changes in lipid profile of HDL cholesterol and levels of triglyceride. " 01/23/1988 - "Triglyceride and high density lipoprotein cholesterol concentrations and body weight did not change appreciably during the study. " 01/01/1988 - "In observational studies with hyperlipidaemic patients with stable body weight and under lipid lowering diet, during the first 4-6 weeks no significant effect on HDL was seen, whereas longterm studies clearly demonstrate an increase in HDL--cholesterol. "
2.	Coronary Disease (Coronary Heart Disease) 06/01/1983 - "Because of its association with longevity and reduced incidence of coronary heart disease, it becomes important to find out how elevated HDL-cholesterol levels are determined. " 08/15/1993 - "For men, improvement in the composite physical activity score significantly correlated with an increase in HDL cholesterol (r = 0.14, p = 0.005) and decreases in body mass index (r = -0.16, p = 0.001) and estimated 10-year coronary heart disease risk score (r = -0.10, p = 0.056). " 03/15/1989 - "The results reveal that HDL-cholesterol percentage had the highest predictive value for risk of future coronary disease; it significantly improved the predictive capability of the logistic regression model, even after adjustment for all other mentioned variables.(ABSTRACT TRUNCATED AT 250 WORDS)" 03/01/1986 - "To test the hypothesis that higher levels of high-density lipoprotein cholesterol (HDL-C) in black men than in white men may offer the former greater protection against coronary heart disease (CAD), the relation between HDL-C and 7-year incidence of CAD was examined in the 5,792 white men and in the 465 black men assigned to the usual-care group of the Multiple Risk Factor Intervention Trial. " 04/01/2000 - "The protective effects of alcoholic against coronary heart disease are mainly related to an increase in HDL cholesterol. "
3.	Insulin Resistance 05/01/2000 - "Statins versus placebo significantly lowered plasma total, LDL-, HDL-cholesterol and triglyceride concentrations and improved insulin resistance and Rq and metabolic control. " 03/31/2015 - "The application of pinpoint plantar long-wavelength infrared light irradiation (PP-LILI) to a patient's sole, at the point where the line drawn between the first and second metatarsal heads intersects with the vertical line from the medial malleolus, was effective in increasing blood flow to the facial artery, elevating high-density lipoprotein cholesterol (HDL-C) levels, and reducing insulin resistance. " 04/01/2012 - "This review focuses on black-white differences in: (1) the lipid profile across North America, Europe, and Africa; (2) the efficacy of TG-based screening tests, specifically the metabolic syndrome and its two abbreviated versions, the hypertriglycerdemic waist and TG/high-density lipoprotein cholesterol (HDL-C) ratio; and (3) the mechanisms that allow TG to be normal even in the presence of insulin resistance. " 06/01/2015 - "The highest vs. the lowest tertile of the fried snacks, sweets, and high-fat dairy pattern was associated with higher homeostasis model assessment of insulin resistance (HOMA-IR) (β: 1.88 mmol/L ⋅ uIU/L) and lower HDL cholesterol (β: -4.48 mg/dL) in a model adjusted for age, sex, study site, and caloric intake (P < 0.05). " 12/01/2012 - "This study aimed to examine the association between an increased ratio of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) and insulin resistance as well as to investigate the interactive effect of TG/HDL-C and waist circumference on insulin resistance in a rural Korean population. "
4.	Atherosclerosis 11/01/1980 - "Improved approaches to the primary prevention of atherosclerosis may be realized by a better understanding of the inverse relationship of body mass to HDL cholesterol levels." 10/01/1990 - "Research shows that PUFA has little effect on high-density-lipoprotein cholesterol (HDL-C) which is protective against atherosclerosis. " 03/01/2003 - "We hypothesized that elevating LPL activity would cause a reduction of plasma TG and increase in HDL cholesterol, resulting in protection against the development of atherosclerosis. " 03/06/1998 - "These results may help to explain observations in the literature that document an increased risk of atherosclerosis in patients with depressed levels of HDL phospholipid even in the face of normal HDL cholesterol levels." 01/01/2015 - "Using published GWAS and 9,713 European Americans (EA) from the Atherosclerosis Risk in Communities (ARIC) study, we identified an interaction between HMGCR and LIPC affecting high-density lipoprotein cholesterol (HDL-C) levels. "
5.	Dyslipidemias (Dyslipidemia) 12/01/2002 - "Improvement in dyslipidemia is characterized by raised high-density lipoprotein cholesterol and lower triglyceride concentrations. " 01/01/2014 - "In this study, we first report an analysis of gene-gene interactions affecting HDL cholesterol (HDL-C) levels in a candidate gene study of 2,091 individuals with mixed dyslipidemia from a clinical trial. " 05/01/2011 - "After an 8-year follow up period, the Bogalusa Heart Study showed that children with low high density lipoprotein cholesterol, high triglyceride levels and high body mass index had a notably increased occurrence of dyslipidemia as adults. " 03/10/2009 - "The association of pediatric low- and high-density lipoprotein cholesterol dyslipidemia classifications and change in dyslipidemia status with carotid intima-media thickness in adulthood evidence from the cardiovascular risk in Young Finns study, the Bogalusa Heart study, and the CDAH (Childhood Determinants of Adult Health) study." 12/01/2007 - "The purpose of this study was to evaluate the prevalence of dyslipidemia according to non-high density lipoprotein cholesterol (non-HDL-C) levels in children and also evaluate serum non-HDL-C levels according to age groups, gender difference and living areas. "

Related Drugs and Biologics

1.	Cholesterol
2.	Triglycerides (Triacylglycerol)
3.	LDL Cholesterol
4.	Lipoproteins (Lipoprotein)
5.	Glucose (Dextrose)
6.	Insulin (Novolin)
7.	Blood Glucose (Blood Sugar)
8.	Apolipoprotein A-I (Apolipoprotein A1)
9.	Gemfibrozil (Lopid)
10.	Niacin (Nicotinic Acid)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Fat-Restricted Diet (Diet, Fat Restricted)
3.	Renal Dialysis (Hemodialysis)
4.	Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
5.	Aftercare (After-Treatment)