Glucose (Dextrose)

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

Also Known As:

Networked: 76676 relevant articles (3459 outcomes, 9241 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Haffner, Steven M: 71 articles (12/2015 - 04/2002)
2.	Shulman, Gerald I: 69 articles (01/2016 - 02/2002)
3.	Holst, Jens J: 69 articles (10/2015 - 03/2002)
4.	Tuomilehto, Jaakko: 67 articles (05/2015 - 05/2002)
5.	Azizi, Fereidoun: 62 articles (12/2015 - 02/2003)
6.	Pacini, Giovanni: 62 articles (09/2015 - 03/2002)
7.	Stumvoll, Michael: 60 articles (10/2015 - 02/2002)
8.	DeFronzo, Ralph A: 59 articles (12/2015 - 06/2002)
9.	Laakso, Markku: 56 articles (01/2016 - 01/2002)
10.	Blüher, Matthias: 54 articles (10/2015 - 10/2005)

Related Diseases

1.	Insulin Resistance 03/15/2010 - "Recent animal studies highlighted a possible interaction between chronic PDE5 inhibition and glucose homeostasis which occurs through a marked improvement of high fat diet induced insulin resistance. " 03/18/2009 - "However, they caused a marked decrease of FBG and a significant improvement on glucose tolerance and insulin resistance in STZ-induced type 2 diabetic mice. " 10/01/2004 - "Intraperitoneal administration of the peptide led to its transduction into various tissues in vivo, and this treatment markedly improved insulin resistance and ameliorated glucose tolerance in diabetic mice. " 08/01/1991 - "High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (Glut 4) in fat cells of rats." 01/01/2016 - "There was a significant reduction in insulin resistance measured by the homeostatic model assessment in the isolated-impaired fasting glucose (p < 0.05) but not in the isolated-impaired glucose tolerance groups (p = 0.59). "
2.	Body Weight (Weight, Body) 02/01/2014 - "Among the most relevant changes measured in body and blood parameters were: (i) a significant reduction in food intake of rats fed γ-conglutin concentrate supplemented pasta and a significant limitation in the body weight increase in rats fed α, β and δ-conglutin isolate supplemented pasta, while the food conversion indices were unchanged; (ii) a reduction in glycaemia upon glucose overload trial, especially in the γ-conglutin concentrate supplemented pasta fed animals, at a dose of 45 mg per kg body weight. " 06/01/2010 - "In conclusion, a 16-week exercise training program improved cardiac autonomic modulation in response to an oral glucose load in obese adults, independently of diabetes status, and in the absence of remarkable changes in body weight, body composition, fitness level, and glycemic control." 04/01/2015 - "The dose of 250 mg/kg body weight exhibited potent antihyperglycemic activity and improved glucose tolerance. " 10/01/2013 - "Chronic studies in mice on high-fat diet showed that CZ5 reduced body weight and improved glucose and lipid metabolism via both increased EE and suppressed energy intake. " 09/01/2015 - "The alkylamides also significantly increased the body weight and improved the oral glucose tolerance of the rats. "
3.	Weight Loss (Weight Reduction) 09/01/2002 - "Higher preoperative fasting glucose best predicted the decrease in TG; improved HOMA %S with weight loss correlated best with HDL-C. " 11/01/2010 - "This improvement in glucose metabolism occurs before marked weight loss in patients undergoing bypass procedures, suggesting a direct effect on the hormonal control of glucose metabolism." 08/01/2009 - "Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss." 03/01/1990 - "After a 30-kg weight loss their glucose and lipid profiles were markedly improved but the thermic effect of glucose was still lower than that of the control subjects (4.2%, p less than 0.001). " 01/01/2011 - "Our study shows that LSG is effective in producing a significant and sustained weight loss and improving glucose homeostasis in severely obese T2DM patients."
4.	Hyperglycemia 05/01/2011 - "Hyperleptinemia reversed hyperglycemia and hyperketonemia in diabetic C57Bl/6J mice and dramatically improved glucose tolerance. " 01/01/1987 - "Since hyperglycemia was improved when adipose tissue metabolism was unaltered, GH-dependent changes occurring in other tissues, such as liver or muscle, most likely contribute to derangements of glucose metabolism in diabetes, even when GH is not elevated. " 06/01/2006 - "There was rapid improvement in hepatic glucose effectiveness following only 3 h of NA infusion (NA3h = 31 +/- 6% suppression of EGP with hyperglycemia vs. NA- = 8 +/- 7%; P<0.01) and complete restoration of glucose effectiveness after 6 h of NA (NA6h = 41 +/- 8% suppression of EGP; P = NS vs. nondiabetic subjects). " 05/01/1992 - "We conclude that a marked decrease in whole-body, muscle, and nonoxidative glucose disposal can be induced by hyperglycemia alone." 08/01/2013 - "In-vivo silencing of miR-135a alleviated hyperglycemia, improved glucose tolerance and significantly restored the levels of IRS2 and p-Akt in the gastrocnemius skeletal muscle of db/db mice without any effect on their hepatic levels. "
5.	Obesity 11/01/2015 - "Sirt6 loss- and gain-of-function studies have generated confounding data regarding the role of this sirtuin on energy and glucose homeostasis, leaving unclear whether activation or inhibition of SIRT6 may be beneficial for the treatment of obesity and/or T2DM. " 12/01/2015 - "Furthermore, Oga (+/-) mice resist high-fat diet-induced obesity with ameliorated hepatic steatosis and improved glucose metabolism. " 04/01/2015 - "These data demonstrate that maternal protein supplement confers the long-term sex-specific beneficial consequences of accelerated growth and improved obesity resistance and glucose tolerance of their offspring." 01/01/2015 - "When fed a high-fat diet, the Vegfc-deficient mice were resistant to obesity and had improved glucose metabolism. " 01/01/2012 - "Altogether, this work shows that the molecule MIC-1/GDF15 might be beneficial for the treatment of obesity as well as perturbations in glucose homeostasis."

Related Drugs and Biologics

1.	Insulin (Novolin)
2.	Blood Glucose (Blood Sugar)
3.	Cholesterol
4.	Triglycerides (Triacylglycerol)
5.	Metformin (Glucophage)
6.	Oxygen
7.	Leptin
8.	Potassium
9.	Adiponectin
10.	Glucagon-Like Peptide 1 (GLP 1)

Related Therapies and Procedures

1.	Oral Administration
2.	Fluid Therapy (Oral Rehydration Therapy)
3.	Injections
4.	Gastric Bypass (Roux-en-Y Gastric Bypass)
5.	Bariatric Surgery