Leukemoid Reaction

04/01/1979 - "Since the discovery of a very high blood histamine level in chronic myelocytic leukemia (CML) 1936, the author could ascertain that this parameter is very useful in the differential diagnosis between CML and various "leukemoid" reactions; in the early diagnosis of CML and in the differential diagnosis between CML and other myeloproliferative disorders. "
07/01/1950 - "Studies on the histamine content of blood, with special reference to leukemia, leukemoid reactions and leukocytoses."
01/01/1949 - "Studies on the Histamine Content of Blood with Special Reference to Leukemia, Leukemoid Reactions and Leukocytoses."

11/01/2015 - "Tigecycline-induced Drug Fever and Leukemoid Reaction: A Case Report."
11/01/2015 - "In this study, we describe a patient in whom tigecycline-induced drug fever and leukemoid reaction (LR) after 3 weeks of therapy for pneumonia.A 62-year-old man developed aspiration pneumonia on February 1, 2015. "

01/01/2014 - "Patients presenting with a leukemoid reaction should be tested for granulocyte colony-stimulating factor/receptor biological axis. "
01/01/2014 - "Granulocyte colony-stimulating factor produced by nonhematopoietic malignant cells is able to induce a leukemoid reaction by excessive stimulation of leukocyte production. "
06/01/1998 - "G-CSF produced by non-hematopoietic malignant cells in particular has been reported to be capable of inducing a leukemoid reaction in the host through intense stimulation of leukocyte production. "
08/01/1995 - "Granulocyte-colony stimulating factor (G-CSF) produced by nonhematopoietic malignant cells has been reported to be capable of inducing a leukemoid reaction in the host through intense stimulation of leukocyte production. "
01/01/2014 - "Urothelial carcinoma of the bladder is rarely associated with a leukemoid reaction and autocrine growth induced by paraneoplastic production of granulocyte colony-stimulating factor. "

05/01/1984 - "Differential leucocyte alkaline phosphatase activity (LAPA) in chronic myeloid leukaemia (CML) and myeloid leukemoid reaction (MLR)."
11/30/1962 - "[Leukocyte alkaline phosphatase in chronic myeloproliferative syndromes and in various leukemoid reactions]."
03/01/1966 - "[Case of acquired hemolytic anemia with leukemoid reaction with special reference to activity of neutrophil alkaline phosphatase]."
11/01/1989 - "We diagnosed a 81-year-old woman as CNL because she showed that sustained leukocytosis dominated by mature neutrophils, hepatosplenomegaly, high neutrophilic alkaline phosphatase (NAP) score, absence of the Ph1 chromosome and no evidence of leukemoid reaction. "
10/01/1988 - "High leucocyte alkaline phosphatase score, absence of hepatosplenomegaly and transient nature of leukemoid reaction differentiated it from chronic myeloid leukemia and acute myeloblastic leukemia. "

10/01/2007 - "The murine mammary carcinoma 4T1 causes a leukemoid reaction with profound granulocytosis coincident with the production of tumour-derived growth factors. "
12/01/2012 - "Three etiologies of the leukocytosis were found in those 105 patients: the major one was paraneoplastic leukemoid reaction which accounted for 56%; the second one was hematopoietic growth factors defect accounting for 30%; 14% patients were caused by infection and Tumor bone marrow involvement. "
02/01/2007 - "Leukemoid reaction is defined as a reactive leukocytosis in response to infection, inflammation, or therapeutic agents such as growth factors and malignancy. "
02/01/2007 - "Murine mammary carcinoma 4T1 induces a leukemoid reaction with splenomegaly: association with tumor-derived growth factors."
09/01/2000 - "Patients with tumors that produce hematopoietic growth factors, such as G-CSF, sometimes exhibit leukemoid reactions. "

07/01/1988 - "[Neonatal leukemoid reaction associated with prenatal administration of corticoids]."
01/01/2013 - "Since there were no signs of neonatal leukaemia, transient myeloid disorder or leucocyte adhesion defect, a leukemoid reaction owing to antenatal corticosteroids, chorioamnionitis and funisitis was diagnosed. "
09/01/1990 - "A case is reported of a true monocytic leukemoid reaction in a patient with myelodysplastic syndrome related to the effect of corticosteroids on the underlying marrow disorder."
10/01/2008 - "Potential triggers for leukemoid reactions in premature infants include prenatal corticosteroids, chorioamnionitis and funisitis or systemic infection. "
01/01/2013 - "Leukemoid reactions are well-recognised in the neonatal intensive care unit population and are associated with antenatal corticosteroids, Down's syndrome, chorioamnionitis, funisitis and perinatal infections. "

09/01/1998 - "Based on these results it appears that autocrine production of GM-CSF is a possible cause of this leukemoid reaction."
06/01/2012 - "We present a patient with large-cell carcinoma of the lung, in which cancer cells generate large amounts of GM-CSF leading to a leukemoid reaction with prominent hypereosinophilia and potentially involved in autocrine tumor stimulation."
02/01/2002 - "Famotidine was discontinued and granulocyte-macrophage colony stimulating factor was administered, with concomitant recovery of the granulocyte count and subsequent development of a leukemoid reaction. "
02/01/2009 - "We diagnosed an 86-year-old woman with chronic neutrophilic leukemia (CNL) because she showed sustained leukocytosis dominated by mature neutrophils, hepatosplenomegaly, high neutrophilic alkaline phosphatase score, absence of the Ph chromosome, low serum level of granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF), and no evidence of leukemoid reaction. "

10/01/2001 - "Increased serum vitamin B12, increased serum urine acid levels and increased leukocyte alkaline phosphatase activity are the associated features in the absence of fever or any other underlying disorder to cause leukemoid reaction. "
08/01/1979 - "Leukemoid reactions may be associated with elevated serum vitamin B12 and uric acid, but the levels are usually lower than those found in chronic neutrophilic leukemia. "
10/06/1990 - "The major features of the 34 collected cases (including the two patients reported here) were persistent leukocytosis simulating a leukemoid reaction, hepatosplenomegaly, hyperuricemia, increased vitamin B12 blood level, increased leukocyte alkaline phosphatase and absence of the Philadelphia chromosome. "
08/01/1990 - "The patient showed sustained mature neutrophilic leukocytosis, splenomegaly, a high leukocyte alkaline phosphatase score, elevated serum vitamin B12 and uric acid, myeloid hyperplasia and absence of ph' chromosome in the bone marrow, with no evidence suggesting this condition to be a leukemoid reaction to an underlying disease. "

10/01/2002 - "Our findings provide further data for the identification of prematures exposed to pro-inflammatory cytokines in utero; the injury responsible for BPD in a subset of prematures may begin with a transient leukemoid reaction."
08/01/1995 - "In blood obtained from patients being treated with hematopoietic cytokines or who have leukemoid reactions, an antiglycolytic agent should be used whenever separation of plasma might be delayed more than 1 hour."
10/01/1993 - "Different cytokines present in the two IMFH tumors appear to be responsible for the eosinophilic leukemoid reaction observed in one case and for the granulocytic leukemoid reaction observed in the other patient. "
10/01/1993 - "Cytokines in inflammatory malignant fibrous histiocytoma presenting with leukemoid reaction."

03/01/1978 - "Leukemoid reaction in BALB/c mice bearing primary tumors induced by 3-methylcholanthrene."
03/01/1978 - "During the growth of five of ten primary tumors that were induced by 3-methylcholanthrene in BALB/cMk and BALB/cMk X C57BL/6F1 mice, leukemoid reactions, characterized by increase in number of granulocytes in peripheral blood, and splenomegaly were observed. "
03/01/1987 - "When a methylcholanthrene-induced fibrosarcoma, BMT-11, and its eight clones were transplanted subcutaneously into syngeneic C57BL/6 mice, leukemoid reaction characterized by a progressive increase in peripheral white blood cells (WBC) and splenomegaly was observed as the tumors grew. "
03/01/1987 - "When a 3-methylcholanthrene (CAS: 56-49-5)-induced fibrosarcoma, BMT-11, and its eight clones were transplanted sc into syngeneic C57BL/6 mice, leukemoid reaction characterized by a progressive increase in peripheral white blood cells (WBCs) and by splenomegaly was observed as the tumors grew. "

09/01/1968 - "Chemotherapy incidental to a leukemoid reaction."
05/01/2003 - "We even managed to monitor the leukemoid reaction response to chemotherapy and radiotherapy."
01/01/2014 - "In our case, leukemoid reaction was related to recurrent cervical carcinoma and sensitive to chemotherapy. "
03/01/1973 - "Leukemoid reaction in acute lymphoblastic leukemia: a response to chemotherapy."
12/01/1968 - "Chemotherapy of a leukemoid reaction in pulmonary carcinoma."

06/01/2002 - "A leukemoid reaction was observed in 2.9% of VLBW infants in our neonatal intensive care unit. "
09/01/1996 - "To prospectively investigate the incidence, significance, and kinetic mechanism responsible for leukemoid reactions in patients in the neonatal intensive care unit (NICU). "
09/01/1996 - "Incidence, significance, and kinetic mechanism responsible for leukemoid reactions in patients in the neonatal intensive care unit: a prospective evaluation."
01/01/2013 - "Leukemoid reactions are well-recognised in the neonatal intensive care unit population and are associated with antenatal corticosteroids, Down's syndrome, chorioamnionitis, funisitis and perinatal infections. "

05/01/1963 - "[Leukemoid reaction after splenectomy in Werlhof's disease]."
01/01/1992 - "The myeloblastic leukemoid reaction in our patient related to overwhelming sepsis, splenectomy and overt hemolysis."
12/01/1959 - "[Histio-erythro-leukemoid reaction and systemic lymphadenopathy following splenectomy in a case of Banti's syndrome]."

08/01/2015 - "Quiz Page August 2015: Leukemoid Reaction and Acute Kidney Injury Following Kidney Transplantation."

07/11/2013 - "Cerebrospinal leukemoid reaction secondary to VZV meninigoencephalitis in an AML patient post allogeneic bone marrow transplantation."