Splenectomy

12/01/1999 - "Splenectomy controlled thrombocytopenia with complete remission achieved in 80% (4 from 5) of the patients and 20% (1 from 5) were refractory to this therapy after a medium follow-up time of 6.5 years. "
08/01/1998 - "After splenectomy, six of nine patients with SLE and all three patients with PAPS gained complete remission of thrombocytopenia. "
01/15/1987 - "Twenty-two of the 23 patients with thrombocytopenia less than 100,000/mm3 had complete remission after splenectomy. "
10/01/1982 - "Splenectomy plays an important role in the management of chronic thrombocytopenia when medical treatment is without effect. "
07/01/1978 - "These findings suggest that splenectomy is beneficial in cases where anaemia and thrombocytopenia are not very severe; in severe cytopenia the operation does not increase the life expectancy."

10/01/2012 - "In an effort to evaluate the most effective and safe treatment of splenomegaly, we compared three methods of surgery for treating splenomegaly, including open splenectomy, laparoscopic splenectomy, and a combination of preoperative splenic artery embolization plus laparoscopic splenectomy. "
06/01/1990 - "The authors conclude that the patients with massive splenomegaly are improved by splenectomy, although it most often is merely a palliative treatment in cases of malignant hemopathy."
10/01/1988 - "We conclude that splenectomy is beneficial for some highly selected patients with the clinical diagnosis of tropical splenomegaly syndrome."
05/01/2002 - "Laparoscopic splenectomy was safe and effective in patients with benign disease, even in cases of marked splenomegaly. "
06/01/2011 - "Hand-assisted laparoscopic splenectomy is a safe and effective technique for the management of spleens larger than 20 cm. The technique results in shorter hospital stays, and it is a good alternative to open splenectomy when treating patients with massive splenomegaly."

10/01/1996 - "This study confirms that there is a significant reduction in energy expenditure following splenectomy for hypersplenism in SS disease. "
01/01/2002 - "Although hypersplenism significantly was improved by splenectomy, no difference in changes in liver volume nor survival probability between the two groups was found. "
01/01/1996 - "At her second admission, splenectomy was performed to remove hypersplenism, and her clinical, radiological and hematological findings improved significantly."
05/16/1992 - "While splenectomy conferred benefit in certain selected cases with hypersplenism, there was no significant overall improvement in the postoperative haematological values and no influence on the rate of blastic transformation. "
10/01/1992 - "Splenectomy is an effective treatment for hypersplenism, although it is not without complications. "

08/01/2006 - "Splenectomy is the most effective treatment for patients with severe autoimmune thrombocytopenia (AITP) who do not have a spontaneous or drug- induced remission. "
10/01/1985 - "It is concluded that splenectomy is beneficial in most adult patients with idiopathic thrombocytopenic purpura and that radiological techniques to measure the size of the spleen may be useful in predicting which patients may relapse."
12/01/1996 - "A prospective clinical study was undertaken to evaluate the rate of complete remission in idiopathic thrombocytopenic purpura after splenectomy, to reveal the influence of preoperative immunosuppression on the postoperative course in groups of patients with different responses to treatment, and to describe possible prognostic factors predicting the postoperative course of idiopathic thrombocytopenic purpura. "
01/01/1988 - "In the other patient who had idiopathic thrombocytopenic purpura, a successful accessory splenectomy was done at the same time as her splenectomy, and was followed by 6 months' complete remission. "
10/15/2006 - "Splenectomy and spontaneous remission in children with chronic idiopathic thrombocytopenic purpura."

05/01/2011 - "Splenectomy is one of the treatments with best results; however the high spontaneous recovery rate in children with cITP, the low percentage of bleeding, and the generally benign outcome should encourage delaying this as long as possible. "
07/01/2003 - "In chronic forms, splenectomy is an effective alternative when the risk of hemorrhage is high, while a watchful attitude seems to be the best option when this risk is absent. "
01/01/1988 - "All patients had marked improvement of their platelet counts and clinical bleeding after splenectomy. "
09/01/2015 - "Esophagogastric devascularization and splenectomy decreased significantly the esophageal variceal size when associated with endoscopic follow-up, being effective for bleeding recurrence prophylaxis."
07/01/2003 - "Continuous infusion of RL combined with splenectomy was followed by significantly less bleeding than bolus infusion of RL and improved survival time compared with untreated animals. "