mouse MIRN29 microRNA

12/01/2023 - "Therefore, the main aim of the study was to evaluate effect of miR-29b expression in vivo on DNMTs, renal fibrosis, glomerular and tubular damage as well as renal morphology in DN. "
01/01/2022 - "This study investigated the functional mechanism of miR-29b in atrial fibrosis in AF. "
01/01/2021 - "In the present study, we aimed to determine whether recombinant rAAV9-mediated miR-29b delivery protects against AngII-induced renal fibrosis and dysfunction. "
01/01/2021 - "Our previous study suggested that miR-29b may attenuate AngII-induced renal intestinal fibrosis in vitro. "
06/01/2020 - "This study concludes that miR-29b regulates the expression of HDAC4 which plays a role in controlling renal fibrosis and podocytes' impairment in DN."

11/28/2009 - "The balance between the activation of ECM production induced by oxidative stress and the protective effects of miR-29b could be a relevant factor in understanding how oxidative damage may lead to increased deposition of ECM in the TM and contribute to the elevation of intra-ocular pressure in glaucoma."
01/01/2015 - "This study suggests that TGF-β2 has a time-effect relationship with Tenon's capsule fibroblasts proliferation from glaucoma patients, and it stimulates Tenon's capsule fibroblast proliferation via suppression of miR-29b expression regulated by Nrf2."
01/01/2015 - "TGF-β2 stimulates Tenon's capsule fibroblast proliferation in patients with glaucoma via suppression of miR-29b expression regulated by Nrf2."
01/01/2015 - "To investigate the role of transforming growth factor-β2 (TGF-β2) in Tenon's capsule fibroblasts proliferation from glaucoma patients and the effect of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and miR-29b mRNA in this process. "
09/01/2015 - "We investigated the efficacy of miR-29b in inhibiting scar formation in rabbits who undergo glaucoma filtering surgery (GFS). "

04/16/2015 - "Therefore, we suggest that restoration of the miR-29b expression using the c-Myc inhibitor might be helpful in suppressing tumor aggressiveness mediated by FHIT loss and consequently improving outcomes in NSCLC patients with tumors with low expression of FHIT."
11/18/2019 - "Mechanistic study using a cancer pathway specific transcriptomic array revealed a significant overexpression of the pro-apoptotic gene BCL2L11 (Bim) in the miR-29b overexpressed PC3 cells, which was further verified in PC3 cells overexpressing miR-29b. "
01/01/2019 - "Notably, therapeutic delivery of miR-29b mimics via R11-SSPEI nanoparticle, whose specificity has been proved by our previous studies, can sensitize the tumor to radiation in a xenograft model. "
01/01/2019 - "These studies form a basis for leukemic cell-targeted delivery of miR-29b as a promising therapeutic approach for CLL and other ROR1+ B-cell malignancies."
01/01/2015 - "Thus, our study demonstrated that overexpression of miR-29b inhibits tumor growth in part by targeting MMP-2. "

01/01/2019 - "This study demonstrates that miR-29b targets ICOS, thereby reverses the imbalance of T helper 1 cells (Th1)/Th2 responses and decreases eosinophils recruitment in the airway, which are key features of allergic airway inflammation. "
01/01/2023 - "The negative feedback between miR-29b and DNMT3A modulates CSE-induced M1 polarization and inflammation in macrophages as well as Klotho promoter methylation in CSE-mediated MH-S. "
01/01/2023 - "In addition, miR-29b expression was distinctly downregulated in CSE-induced MH-S cells and inhibited CSE-induced M1 polarization and inflammation. "
01/01/2022 - "MiR-29b can inhibit Th2 cell differentiation by inhibiting B7-H3 and STAT3 pathways at the same time, and reduce asthmatic immune inflammation."
01/01/2022 - "miR-29b plays a hepatoprotective role in alcohol-induced inflammation and liver injury by targeting STAT3."

06/27/2022 - "In our previous study, repressing miR-29b has been shown to reduce muscle atrophy. "
03/14/2023 - "In summary, we experimentally identified and demonstrated a novel small-molecule inhibitor of miR-29b that could act as a potential therapeutic agent for muscle atrophy."
03/14/2023 - "Identification of a novel small-molecule inhibitor of miR-29b attenuates muscle atrophy."
11/01/2022 - "Exercise attenuates AngⅡ-induced muscle atrophy by activation of PPARγ and suppression of miR-29b."
11/01/2022 - "In AngⅡ-induced muscle atrophy mice models, PPARγ was elevated whereas miR-29b was decreased by exercise. "