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Biomarkers (Surrogate Marker)

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, ENVIRONMENTAL EXPOSURE and its effects, disease diagnosis; METABOLIC PROCESSES; SUBSTANCE ABUSE; PREGNANCY; cell line development; EPIDEMIOLOGIC STUDIES; etc.
Also Known As:
Surrogate Marker; Surrogate Endpoint; Surrogate Markers; Surrogate End Points; Biological Marker; Biochemical Marker; Biologic Marker; Biologic Markers; Clinical Marker; Immune Marker; Immune Markers; Immunologic Marker; Laboratory Marker; Marker, Biochemical; Marker, Biological; Marker, Clinical; Marker, Immunologic; Marker, Laboratory; Marker, Serum; Marker, Surrogate; Serum Marker; Surrogate End Point; Surrogate Endpoints; Viral Marker; End Point, Surrogate; End Points, Surrogate; Endpoint, Surrogate; Endpoints, Surrogate; Marker, Biologic; Marker, Immune; Marker, Viral; Markers, Biologic; Markers, Immune; Biochemical Markers; Biological Markers; Biomarker; Clinical Markers; Immunologic Markers; Laboratory Markers; Markers, Biochemical; Markers, Biological; Markers, Clinical; Markers, Immunologic; Markers, Laboratory; Markers, Serum; Markers, Surrogate; Markers, Viral; Serum Markers; Viral Markers
Networked: 240291 relevant articles (7879 outcomes, 42077 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Zetterberg, Henrik: 772 articles (12/2022 - 11/2005)
2. Blennow, Kaj: 699 articles (12/2022 - 03/2000)
3. Zhang, Wei: 429 articles (12/2022 - 04/2002)
4. Wang, Wei: 411 articles (10/2022 - 09/2002)
5. Wang, Jing: 331 articles (11/2022 - 09/2006)
6. Zhang, Jing: 299 articles (12/2022 - 05/2003)
7. Alzheimer's Disease Neuroimaging Initiative: 286 articles (11/2022 - 11/2008)
8. Alzheimer’s Disease Neuroimaging Initiative: 286 articles (10/2022 - 09/2010)
9. Li, Yan: 270 articles (10/2022 - 02/2005)
10. Li, Wei: 269 articles (10/2022 - 01/2006)

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation (Inflammations)
3. Breast Neoplasms (Breast Cancer)
02/10/2017 - "We evaluated the performance of dwgLASSO for survival time prediction using two microarray breast cancer datasets previously reported by Bild et al. and van de Vijver et al. Compared with the top 10 significant genes selected by conventional differential gene expression analysis method, the top 10 significant genes selected by dwgLASSO in the dataset from Bild et al. led to a significantly improved survival time prediction in the independent dataset from van de Vijver et al. Among the 10 genes selected by dwgLASSO, UBE2S, SALL2, XBP1 and KIAA0922 have been confirmed by literature survey to be highly relevant in breast cancer biomarker discovery study. "
01/01/2022 - "One of the most important developments in the breast cancer field has been an improved understanding of prognostic and predictive biomarkers, of which TILs are increasingly gaining importance. "
12/15/2021 - "The results indicate that ML-assisted analysis exhibits higher diagnostic performance even using a single marker for breast cancer diagnosis, and demonstrate improved diagnostic performance under the best combination of biomarkers and suitable ML diagnostic model. "
01/01/2020 - "Together, these findings suggest that the miR-30a rs763354 SNP is an important regulator of breast cancer risk, thus making it a potentially viable prognostic biomarker and one that can be used to guide therapeutic treatment in affected patients."
02/01/2014 - "Advances in identifying biomarker profiles in patients with early-stage breast cancer have improved 5-year curative rates. "
4. Disease Progression
5. Infections

Related Drugs and Biologics

1. Biomarkers (Surrogate Marker)
2. Proteins (Proteins, Gene)
3. MicroRNAs (MicroRNA)
4. Immune Checkpoint Inhibitors
5. C-Reactive Protein
6. Lipids
7. Cytokines
8. Antioxidants
9. Glucose (Dextrose)
10. Vaccines

Related Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Drug Therapy (Chemotherapy)
4. Precision Medicine
5. Neoadjuvant Therapy