Filtering Surgery

A surgical procedure used in treatment of glaucoma in which an opening is created through which aqueous fluid may pass from the anterior chamber into a sac created beneath the conjunctiva, thus lowering the pressure within the eye. (Hoffman, Pocket Glossary of Ophthalmologic Terminology, 1989)

Also Known As:

Networked: 1115 relevant articles (71 outcomes, 113 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Khaw, P T: 9 articles (02/2004 - 03/2000)
2.	Van Bergen, Tine: 8 articles (11/2015 - 11/2009)
3.	Moons, Lieve: 8 articles (11/2015 - 11/2009)
4.	Stalmans, Ingeborg: 8 articles (11/2015 - 11/2009)
5.	Sherwood, Mark B: 8 articles (01/2015 - 02/2004)
6.	Schultz, Gregory S: 8 articles (01/2015 - 11/2003)
7.	Khaw, Peng T: 8 articles (11/2013 - 03/2002)
8.	Krieglstein, G K: 8 articles (02/2008 - 01/2000)
9.	Vandewalle, Evelien: 7 articles (11/2015 - 11/2011)
10.	Wong, Tina T: 7 articles (01/2015 - 01/2010)

Related Diseases

1.	Glaucoma 02/01/2009 - "If glaucoma filtration surgery is required, there are generally good results. " 02/01/2009 - "The three eyes that had glaucoma filtration surgery had good outcomes. " 12/01/2004 - "Glaucoma filtration surgery in pseudophakic eyes significantly improved IOP and reduced glaucoma medication requirements while maintaining stability of vision. " 09/01/2003 - "These results support the hypothesis that filtering surgery (trabeculectomy) or combined surgery (phacotrabeculectomy) in patients with advanced glaucoma are associated with a significant improvement of the mean defect in standard automated perimetry without a significant change of LV defect." 02/01/2000 - "Postoperative values for anterior chamber depth were significantly greater in patients with glaucoma who underwent combined surgery, but no significant changes were observed in those who underwent filtration surgery alone. "
2.	Blister (Bulla) 09/01/2006 - "Needle revision of the filtering bleb is a simple and safe technique that offers good results even years after a filtering surgery had been performed. " 01/01/2012 - "The majority of complications seen in filtering surgery are largely eliminated by the nonpenetrating and bleb-independent approach. " 01/01/2010 - "Efficacy of amniotic membrane-assisted bleb revision for elevated intraocular pressure after filtering surgery." 11/01/2005 - "In vivo confocal microscopy study of blebs after filtering surgery." 02/01/1997 - "This study shows that a substantial, transient decrease of IOP after DOP occurs in glaucomatous eyes with a well-functioning bleb 3 months to 6 years after filtering surgery. "
3.	Cicatrix (Scar) 01/01/2008 - "Inhibition of CTGF expression may be effective in preventing undesirable scar formation during healing following filtration surgery." 01/01/2006 - "Smad7 gene transfer modulates injury-induced wound healing of conjunctival tissue in mice, suggesting that this strategy may be effective in preventing excessive scarring following filtration surgery. " 01/01/2014 - "Thus, CTGF could potentially be a safer and more efficient target than TGF-β at suppressing scar formation after filtering surgery." 12/01/2013 - "We investigated the hypothesis that placental growth factor (PlGF) plays a role in post-operative scar formation, and that it therefore may be a target for improvement of filtration surgery outcome. " 04/01/2013 - "The main disadvantage of these mostly non-penetrating procedures is the induction of conjunctival scarring which jeopardizes subsequent filtering surgery. "
4.	Neovascular Glaucoma 05/01/2005 - "Vitrectomy combined with filtering surgery is considered to be an effective treatment for neovascular glaucoma to maintain the visual function for a long period." 09/01/1988 - "The visual acuities remained within one line of their preoperative levels or improved in 31 (76%) of the 41 aphakic or pseudophakic eyes with non-neovascular glaucomas; 3 (30%) of the 10 phakic eyes with non-neovascular glaucomas after failed filtering surgery; 10 (67%) of the 15 eyes with neovascular glaucomas; and 9 (100%) of the 9 eyes with non-neovascular glaucomas in patients younger than 13 years of age on whom Snellen acuity was available.(ABSTRACT TRUNCATED AT 250 WORDS)" 12/01/1986 - "The visual acuities remained within one line of their preoperative levels or improved in 38 (79%) of the 48 aphakic eyes with non-neovascular glaucoma, 11 (69%) of the 16 phakic eyes with non-neovascular glaucoma after unsuccessful filtering surgery, and 12 (75%) of the 16 eyes with NVG. " 05/01/2009 - "[Antiangiogenic treatment for neovascular glaucoma and after filtering surgery]." 05/01/2005 - "Twenty-one eyes with neovascular glaucoma underwent pars plana vitrectomy combined with filtering surgery between January 1995 and December 2003. "
5.	Open-Angle Glaucoma (Glaucoma, Open Angle) 08/01/2002 - "In eyes with open-angle glaucoma, viscocanalostomy is less effective in reducing intraocular pressure than standard filtering surgery. " 12/01/1996 - "When intraocular pressure is used as a therapeutic end point, both filtration surgery and medical therapy appear to be equally effective in maintaining long-term visual function and a stable optic disk in chronic open-angle glaucoma." 12/01/2012 - "Thus, our prospective data do not support the procedure of IDK as 'the gold standard' for filtering surgery in patients with open-angle glaucoma." 01/01/2006 - "Retrospective non randomised study including 171 eyes (136 patients), mean age: 63.9 years) with medically uncontrolled open-angle glaucoma and without previous filtering surgery. " 02/01/2004 - "32 eyes of 32 primary open-angle glaucoma(POAG) patients who underwent NPT as the first filtering surgery were enrolled in the study. "

Related Drugs and Biologics

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2.	bevacizumab
3.	Fluorouracil (Carac)
4.	ranibizumab (Lucentis)
5.	Cytarabine (Cytosar-U)
6.	Ophthalmic Solutions (Eye Drops)
7.	Antimetabolites
8.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9.	Hydrogel
10.	Paclitaxel (Taxol)

Related Therapies and Procedures

1.	Trabeculectomy (Trabeculoplasty)
2.	Vitrectomy
3.	Injections
4.	Lasers (Laser)
5.	Cataract Extraction