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succinylconcanavalin A
Also Known As:
succinyl-ConA; succinyl-concanavalin A; succinylated concanavalin A; concanavalin A, hydrogen butanedioate (ester)
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Lectins: 6782
Plant Lectins: 206
Concanavalin A: 2877
succinylconcanavalin A: 6
Plant Proteins: 334
Plant Lectins: 206
Concanavalin A: 2877
succinylconcanavalin A: 6
Related Diseases
1.
Neoplasms (Cancer)
10/01/1985 - "
Wheat-germ lectin and succinyl concanavalin A reacted with all 19 tumors, whereas other lectins bound to some, but never to all, tumors in either group.
"
08/17/1981 - "
Incubation of tumor cells with concanavalin A prior to addition of 125I-labelled insulin resulted in a reduction of insulin-binding capacity; succinyl-concanavalin A did not affect binding of insulin.
"
2.
Wounds and Injuries (Trauma)
03/01/1988 - "
A similar region-specific distribution of adherent bacteria was found when corneas were inverted in the bacterial suspension and when corneas were incubated in the bacterial suspension for 15 rather than 30 min. Corneas preincubated with the lectin, succinyl-concanavalin A, showed significantly decreased bacterial adherence, indicating a possible role for mannose moieties of wound surface glycoconjugates in bacterial adherence.
"
3.
Retinoblastoma (Glioblastoma, Retinal)
01/01/1993 - "
The growth and differentiation potential of Y79 human retinoblastoma cells was assessed in vitro following treatment with the differentiating agent succinylated concanavalin A (SCA).
"
01/01/1993 - "
Differentiation of Y79 retinoblastoma cells induced by succinylated concanavalin A.
"
4.
Infections
04/01/1981 - "
Treatment prior to infection with Trypanosoma cruzi trypomastigotes of Vero, MA-103, and chick muscle cells with concanavalin A, phytohemagglutinin, wheat germ agglutinin and ricin I results in a diminished parasite interiorization in these cells; succinylated concanavalin A is also inhibitory.
"
5.
Hepatocellular Carcinoma (Hepatoma)
12/04/1979 - "
2. Concanavalin A stimulated the specific Ca2+ binding to liver and hepatoma plasma membranes, showing a maximal stimulation (3--5-fold) at 100 microgram/ml. Succinyl concanavalin A was less effective, whereas wheat germ agglutinin and ricinus lectin were ineffective.
"
Related Drugs and Biologics
1.
Wheat Germ Agglutinins
2.
Concanavalin A
3.
Lectins
4.
Ricin
5.
Suspensions
6.
Phytohemagglutinins
7.
Mannose (D-Mannose)
8.
Insulin (Novolin)
9.
Glycoconjugates