Erosive Adenomatosis of the Nipple

A rare benign neoplasm that arises in the area of the nipple; lesions resemble those of PAGET'S DISEASE, MAMMARY. Morphologically, there is proliferation of ducts lined with epithelial and myoepithelial cells and focal erosion of the epidermis.

Also Known As:

Networked: 18 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Eczema
2.	Bowen's Disease (Disease, Bowen)
3.	Neoplasms (Cancer)
4.	Adenomyoepithelioma
5.	Acrospiroma

Experts

1.	Bimpa, Kanelina: 1 article (05/2022)
2.	Bobos, Mattheos: 1 article (05/2022)
3.	Charitou, Theodosia: 1 article (05/2022)
4.	Kantounis, Konstantinos: 1 article (05/2022)
5.	Tsakos, Elias: 1 article (05/2022)
6.	Xydias, Emmanouil: 1 article (05/2022)
7.	Ziogas, Apostolos C: 1 article (05/2022)
8.	Wang, Juan: 1 article (09/2021)
9.	Yin, Rui: 1 article (09/2021)
10.	Zhang, Lian: 1 article (09/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Erosive Adenomatosis of the Nipple:

1.	AntibodiesIBA 03/01/1993 - "These findings are helpful for differentiating Paget's disease from other lesions of the nipple, namely Bowen's disease and eczema which do not react with both antibodies, and from nipple adenoma which exhibits a positive staining with anti-EMA antibody and no reactivity with anti-c-erbB-2 antibody."
2.	Progesterone Receptors (Progesterone Receptor)IBA 03/01/2011 - "Nevertheless, we have not found any studies on HER2/neu status, estrogen receptors, or progesterone receptors in nipple adenoma of male patients. "
3.	Estrogen ReceptorsIBA 03/01/2011 - "Nevertheless, we have not found any studies on HER2/neu status, estrogen receptors, or progesterone receptors in nipple adenoma of male patients. "
4.	Indicators and Reagents (Reagents)IBA 01/01/2014 - "Bilateral florid papillomatosis of the nipple: an unusual indicator for metachronous breast cancer development-a case report."
5.	DNA (Deoxyribonucleic Acid)IBA 05/01/1990 - "The immunohistochemical and DNA profiles of two cases of florid papillomatosis of the nipple (FPN) were compared with the immunohistochemical and DNA profiles of mammary intraductal carcinomas (IC) to assess the relationship between these two proliferative neoplasms. "
6.	AcidsIBA 09/01/2021 - "5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: A case report."
7.	CalponinsIBA 01/01/2023 - "WT1, p63, and calponin immunostains were performed on normal and lesional tissues from the breast (adenosis, sclerosing adenosis, lactating adenoma, nipple adenoma, tubular adenoma, adenomyoepithelioma, and adenoid cystic carcinoma [ACC]), skin (cutaneous mixed tumor, hidradenoma, spiradenoma, and ACC), and salivary gland (pleomorphic adenoma and ACC). "
8.	5-hydroxymethylcytosineIBA 05/01/2016 - "5-Hydroxymethylcytosine as a putative marker for erosive adenomatosis of the nipple."
9.	1-phenyl-3,3-dimethyltriazene (PDT)IBA 09/01/2021 - "5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: A case report."

Therapies and Procedures

1.	Mohs Surgery (Mohs' Micrographic Surgery) 01/01/2020 - "Successful Treatment of Nipple Adenoma Using Mohs Micrographic Surgery to Preserve the Nipple-Areolar Complex." 05/01/2016 - "Utilizing Mohs Surgery for Tissue Preservation in Erosive Adenomatosis of the Nipple." 10/01/2002 - "Erosive adenomatosis of the nipple: Conservation of nipple by Mohs micrographic surgery." 06/01/1998 - "Mohs micrographic surgery for an erosive adenomatosis of the nipple."
2.	Cryosurgery 04/01/2021 - "Cryosurgery as a Minimally Invasive Alternative Treatment for a Patient with Erosive Adenomatosis of the Nipple." 09/01/2016 - "Nipple Adenoma: New Images and Cryosurgery Treatment." 02/01/1998 - "Erosive adenomatosis of the nipple treated with cryosurgery."
3.	Sutures (Suture) 08/01/2006 - "A case of erosive adenomatosis of nipple treated with total excision using purse-string suture." 05/01/2022 - "Double purse-string suture surgical wound closure after excision of nipple adenoma of the breast: A case report."
4.	Photochemotherapy (Photodynamic Therapy) 09/01/2021 - "5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: A case report."
5.	Mastectomy (Mammectomy) 01/01/2007 - "Nipple adenoma found in a mastectomy specimen: report of a case with special regard to the proliferation pattern." 01/01/2007 - "We report a case of nipple adenoma incidentally found in a mastectomy specimen, and describe its unique histological appearance and the immunohistochemical distribution of Ki-67 positive tumor cells. "