Acids

Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant & Hackh's Chemical Dictionary, 5th ed)

Networked: 3146 relevant articles (110 outcomes, 279 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hammock, Bruce D: 19 articles (12/2015 - 12/2003)
2.	Zeldin, Darryl C: 16 articles (07/2015 - 11/2003)
3.	Falck, John R: 16 articles (07/2015 - 08/2005)
4.	Wajner, Moacir: 11 articles (09/2010 - 11/2002)
5.	Imig, John D: 9 articles (03/2015 - 10/2005)
6.	Nithipatikom, Kasem: 9 articles (06/2013 - 02/2006)
7.	Gross, Garrett J: 9 articles (06/2013 - 08/2006)
8.	Akihisa, Toshihiro: 9 articles (03/2013 - 04/2002)
9.	Tokuda, Harukuni: 8 articles (03/2013 - 04/2002)
10.	Wang, Dao Wen: 7 articles (01/2014 - 06/2005)

Related Diseases

1.	Neoplasms (Cancer) 03/01/1986 - "Our results demonstrate that gammalinolenic, arachidonic and eicosapentaenoic acids are highly effective in killing human breast, lung, and prostate tumor cells while leaving normal cells viable. " 01/01/2006 - "Phenolic acids are widespread in plant foods; they contain important biological and pharmacological properties, some of which were shown to be effective in preventing cancer. " 10/01/2005 - "Pattern recognition techniques, principal component analysis (PCA) and hierarchical cluster analysis (HCA) were employed to reduce dimensionality and investigate which subset of variables could be more effective for classifying the ganoderic acids according to their degree of cytotoxicities against tumor cells. " 12/09/2015 - "Evaluation of the "shapeshifting" properties of 2,2'-, 2,4'-, and 4,4'-linked variants of the secalonic acids A in a polar solvent in conjunction with assays of the compounds against select cancer cell lines was conducted to study possible correlations between linkage variation and cytotoxicity. " 10/01/2013 - "We estimated the intake of phenolic acids and their food sources and associated lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. "
2.	Inflammation 12/01/1995 - "Supplementation of long-chain omega-3-fatty acids may be beneficial for reducing excessive inflammation in CF patients and should be further evaluated." 11/27/2013 - "In this study, we investigated the effects and underlying molecular mechanisms of hexahydro-β-acids (HBAs) on 12-O-tetradecanoylphorbol-13-acetate (TPA)-stimulated mouse skin inflammation and in the two-stage carcinogenesis model. " 09/01/2015 - "Together, these acids and 15-LOX-1 are the driving force for the resolution of acute and chronic inflammation in normal cells. " 01/01/2015 - "Impact of dietary organic acids and botanicals on intestinal integrity and inflammation in weaned pigs." 03/01/2014 - "Myristic (14:0), palmitic (16:0), palmitoleic (16:1n-7), and dihomo-γ-linolenic (20:3n-6) acids were positively associated with all markers of inflammation. "
3.	Infection 01/01/2007 - "A significant increase in phenolic acids was also detected, and this was the reason for improved plant resistance to pathogen infection. " 07/01/1979 - "Protection against infection with these organisms appears to be related to high concentrations of volatile acids, low pH, and low oxidation-reduction potential of the intestinal contents of animals with an intact flora. " 07/01/2004 - "Efficacy of organic acids in hand cleansers for prevention of rhinovirus infections." 09/01/1998 - "Urinary excretion of organic acids was studied by gas chromatography-mass spectrometry in 39 infants with four types of PEM: 1) upon hospital admission, as soon as eventual infections had been cleared, and salt and water deficits corrected, but before oral feeding was started; 2) after start of protein alimentation; 3) on the day of discharge. " 01/01/2013 - "These new findings demonstrate that trans-3-aryl acrylic acids and their derivatives represent a new template for antiviral studies and could be considered for novel therapy against plant virus infection."
4.	Cardiovascular Diseases (Cardiovascular Disease) 05/01/2013 - "The beneficial effects of omega-3-fatty acids on cardiac and extra cardiac organs have been extensively studied in the last two decades, and continue to show great promise in the primary and secondary prevention of cardiovascular diseases (CVDs). " 07/01/2015 - "Increased CYP epoxygenase activity and consequently up regulation of epoxyeicosatrienoic acids (EETs) levels provides protection against metabolic syndrome and cardiovascular diseases. " 12/01/2015 - "Epoxyeicosatrienoic acids (EETs) have beneficial effects on cardiovascular disease. " 01/01/2014 - "Inside epoxyeicosatrienoic acids and cardiovascular disease." 04/01/2013 - "transFatty acids (TFAs) increase cardiovascular disease risk. "
5.	Ulcerative Colitis 04/01/1992 - "In this study, we evaluated the efficacy of ingestion of fish oil n-3-omega-fatty acids, inhibitors of leukotriene synthesis, in the treatment of ulcerative colitis. " 02/01/2012 - "Efficacy of 5-aminosalicylic acids (5-ASAs) in ulcerative colitis (UC) has been studied previously in meta-analyses. " 04/01/2011 - "The efficacy of 5-aminosalicylic acids (5-ASAs) in ulcerative colitis (UC) has been studied previously in meta-analyses. " 04/01/1990 - "We evaluated the efficacy of fish oil n--3-omega-fatty acids, inhibitors of leukotriene synthesis, in the treatment of ulcerative colitis. " 01/01/2009 - "Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis."

Related Drugs and Biologics

1.	Arachidonic Acid (Vitamin F)
2.	Bile Acids and Salts (Bile Acids)
3.	Fatty Acids (Saturated Fatty Acids)
4.	Cytochrome P-450 Enzyme System (Cytochrome P450)
5.	Enzymes
6.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
7.	Antioxidants
8.	caffeic acid
9.	Oleanolic Acid
10.	Esters

Related Therapies and Procedures

1.	Chemoprevention
2.	Emergency Treatment
3.	Transplants (Transplant)
4.	Knee Replacement Arthroplasty (Total Knee Replacement)
5.	Air Bags (Airbags)