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Glandular and Epithelial Neoplasms (Neoplasms, Glandular)

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Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.

Also Known As:

Neoplasms, Glandular; Epithelial Neoplasms, Glandular; Neoplasms, Glandular and Epithelial; Epithelial Neoplasms; Glandular Neoplasms; Neoplasms, Epithelial; Neoplasms, Glandular Epithelial; Epithelial Neoplasm; Epithelial Neoplasm, Glandular; Glandular Epithelial Neoplasm; Glandular Epithelial Neoplasms; Glandular Neoplasm; Neoplasm, Epithelial; Neoplasm, Glandular; Neoplasm, Glandular Epithelial

Networked: 332 relevant articles (9 outcomes, 38 trials/studies)

Relationship Network

Disease Context: Research Results

Neoplasms: 649836
- Neoplasms by Histologic Type: 1
  - Glandular and Epithelial Neoplasms: 332

Related Diseases

1.	Neoplasms (Cancer)
2.	Carcinoma (Carcinomatosis)
3.	Melanoma (Melanoma, Malignant)
4.	Granulosa Cell Tumor
5.	Mesothelioma

Experts

1.	Amin, Mahul B: 5 articles (02/2009 - 03/2002)
2.	Cohen, Cynthia: 4 articles (08/2010 - 02/2003)
3.	Terzi, Alberto: 3 articles (09/2014 - 07/2013)
4.	Viti, Andrea: 3 articles (09/2014 - 07/2013)
5.	Bertolaccini, Luca: 3 articles (09/2014 - 07/2013)
6.	Yang, Ximing J: 3 articles (02/2008 - 04/2006)
7.	Young, Andrew N: 3 articles (10/2007 - 02/2003)
8.	Hashimoto, Yosuke: 3 articles (01/2006 - 01/2004)
9.	Weiss, L M: 3 articles (05/2002 - 09/2000)
10.	Silva, Elvio G: 2 articles (01/2016 - 06/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Glandular and Epithelial Neoplasms:

1.	Keratins (Keratin)IBA 03/01/2011 - "This study aimed to identify relevant keratin subtypes that may associate with the pathogenesis of oral epithelial neoplasms. " 12/01/1989 - "Immunohistochemical study on keratin expression in certain cutaneous epithelial neoplasms. " 09/01/2015 - "Our results reinforce that a subset of head and neck EFTs may show strong cytokeratin expression or focal keratinization, and are therefore histologically indistinguishable from more common true epithelial neoplasms. " 01/01/2011 - "The expression patterns of cytokeratin (CK) filaments in human epithelial neoplasms are complex and distinctive. " 12/01/2003 - "Cytokeratin (CK)7 and CK20, the low molecular weight cytokeratins, have been found to have a benefit in the differential diagnosis of some epithelial neoplasms. "
2.	VimentinIBA 12/01/2007 - "Immunohistochemical expression of vimentin has been used in the differential diagnosis of renal epithelial neoplasms. " 09/01/1990 - "The neoplastic cells of these tumors expressed only vimentin intermediate filaments and showed no other immunohistochemical features of epithelial neoplasms, although they exhibited a metastatic pattern characteristic of lung carcinomas. " 09/01/1987 - "However, many epithelial cells in tissue culture or in effusion, as well as cells in some solid epithelial neoplasms such as renal, endometrial, ovarian, pulmonary, and thyroid adenocarcinomas, have been shown to coexpress vimentin and keratin. " 03/01/2003 - "Histologically, the lesion had the appearance of an anaplastic neoplasm, and a panel of immunohistochemical markers including vimentin, MART-1, S100 protein, HMB-45, smooth muscle actin, common muscle actin, desmin, CD31, CD34, CD68, EMA and cytokeratins, was helpful in excluding melanoma, as well as other mesenchymal and epithelial neoplasms." 11/01/2009 - "Twenty-one canine primary pulmonary epithelial neoplasms were evaluated for the co-expression of cytokeratin and vimentin. "
3.	HormonesIBA 02/01/1998 - "Protective effects were highest for epithelial neoplasms, but were also observed for hormone-related neoplasms. " 01/01/2016 - "We believe that, most probably, ovarian epithelial neoplasms are related to hormones and the identification of these hormones will allow us not only to diagnose and treat these lethal neoplasms, but also to prevent them. " 10/01/2014 - "We considered the age-specific incidence of all non-hormone-related epithelial neoplasms after a first primary colorectal cancer (n = 9542) in the Vaud Cancer Registry data set. " 11/01/1998 - "These observations, together with our previous finding that testosterone induces neoplasms with a predominantly glandular pattern, establish the guinea pig as an excellent animal to study ovarian neoplasms, confirm the significance of hormones in the development of ovarian epithelial tumors, and suggest that the different histologic appearance of ovarian epithelial neoplasms might be related to different hormonal effects."
4.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/01/2015 - "Improved Survival with Anti-VEGF Therapy in the Treatment of Unresectable Appendiceal Epithelial Neoplasms." 01/01/2001 - "In this study, we investigated whether serum VEGF and bFGF levels could be predictors of the development and extension of thymic epithelial neoplasms. " 08/01/2015 - "Anti-VEGF agents should be strongly considered in the management of patients with higher-grade appendiceal epithelial neoplasms who are suboptimal candidates for surgical resection." 01/01/2002 - "The angiogenesis and enhancement of vascular permeability induced by VEGF represents a new hypothesis for the release of the CA 125 antigen into the circulation in patients with ovarian epithelial neoplasm." 01/01/2001 - "Elevated serum vascular endothelial growth factor and basic fibroblast growth factor levels in patients with thymic epithelial neoplasms."
5.	Fluorouracil (Carac)FDA LinkGeneric 11/15/2004 - "Vector targeting makes 5-fluorouracil chemotherapy less toxic and more effective in animal models of epithelial neoplasms." 01/01/1993 - "Resection of a solid and papillary epithelial neoplasm of the pancreas following treatment with cis-platinum and 5-fluorouracil: a case report."
6.	Mitomycin (Mitomycin-C)FDA LinkGeneric 05/01/2008 - "Reduction of Shh expression might be involved in the therapeutic efficacy of topical mitomycin C for ocular surface epithelial neoplasms."
7.	DesminIBA 03/01/2003 - "Histologically, the lesion had the appearance of an anaplastic neoplasm, and a panel of immunohistochemical markers including vimentin, MART-1, S100 protein, HMB-45, smooth muscle actin, common muscle actin, desmin, CD31, CD34, CD68, EMA and cytokeratins, was helpful in excluding melanoma, as well as other mesenchymal and epithelial neoplasms."
8.	LBH589IBA 08/01/2009 - "The HDAC inhibitor LBH589 is effective in treating some haematological neoplasms and shows promise for certain epithelial neoplasms. "
9.	bevacizumab FDA Link 08/01/2015 - "Bevacizumab in combination with chemotherapy appears to play a role in surgically unresectable appendiceal epithelial neoplasm patients, with an improvement in PFS and OS. "
10.	claudin 4IBA 09/01/2007 - "Claudin 4 identifies a wide spectrum of epithelial neoplasms and represents a very useful marker for carcinoma versus mesothelioma diagnosis in pleural and peritoneal biopsies and effusions."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 06/01/2008 - "Prospective randomized clinical trials and an international registry of patients who have Thymic epithelial neoplasms are needed to stratify patients who may benefit from neoadjuvant chemotherapy, postoperative radiation therapy, and other nonsurgical modalities." 08/01/2015 - "Currently, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are accepted treatments for surgically resectable appendiceal epithelial neoplasms. " 06/01/2014 - "Our aim is to investigate the gender differences for metastatic epithelial neoplasms of the appendix treated by cytoreductive surgery (CS) and intraperitoneal chemotherapy (IPC). " 06/01/2005 - "Current chemotherapy options for thymic epithelial neoplasms." 06/01/1999 - "Immunohistochemical markers of cell cycle control applied to ovarian and primary peritoneal surface epithelial neoplasms: p21(WAF1/CIP1) predicts survival and good response to platinin-based chemotherapy."
2.	Combined Modality Therapy 11/01/2012 - "Diagnosis, multimodal treatment and follow-up of thymic epithelial neoplasms require a multidisciplinary approach where surgery is the cornerstone treatment. "
3.	Nephrectomy 04/01/2007 - "Partial nephrectomy revealed an epithelial neoplasm with multilocular cystic renal cell carcinoma pattern. " 12/01/2003 - "A total of 53 radical nephrectomy specimens with renal epithelial neoplasms (nine oncocytoma, seven chromophobe RCC, four papillary RCC and 33 clear cell RCC) were included in this study. "
4.	Surgical Instruments (Clip) 10/01/2011 - "The study included 764 patients in whom 924 gastric epithelial neoplasms were resected endoscopically between June 2005 and December 2009: the period during which preventative coagulation for all exposed vessels on the artificial ulcer with hemostatic forceps upon completion of ESD was performed routinely. "
5.	Radiotherapy 02/01/2013 - "Relevance of dermatologic radiotherapy in the therapeutic strategy of skin epithelial neoplasms: excellent results in the treatment of lesions localized on eyelids and skin overlying the cartilage of the nose." 10/01/1999 - "Results and side effects of dermatologic radiotherapy: a retrospective study of irradiated cutaneous epithelial neoplasms." 11/01/1965 - "[Epithelial neoplasms of the scalp (late results of radiotherapy)]." 12/01/1967 - "[Association of radiotherapy and chemotherapy in the treatment of epithelial neoplasms. " 10/17/1966 - "[Observations on the combined use of methylhydrazine and radiotherapy in epithelial neoplasms]."