Saponins

Subscribe to Selected New Research on Saponins

744 relevant articles (52 outcomes, 95 trials/studies) found for this Bio-Agent

Description: Sapogenin glycosides. A type of glycoside widely distributed in plants. Each consists of a sapogenin as the aglycon moiety, and a sugar. The sapogenin may be a steroid or a triterpene and the sugar may be glucose, galactose, a pentose, or a methylpentose. Sapogenins are poisonous towards the lower forms of life and are powerful hemolytics when injected into the blood stream able to dissolve red blood cells at even extreme dilutions.

Also Known As:

Saponin

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 2945

Glycosides: 357

Saponins: 744

digoxin-like factors: 133

22-O-angeloylcamelliagenin C-3-O-(glucopyranosyl-1-2)(glucopyranosyl-1-2-O-arabinopyranosyl-1-3-)glucopyranosiduronic acid: 4

methyl protodioscin: 4

OSW 1: 4

polysponin: 4

tiqueside: 4

buddlejasaponin IV: 3

formosanin C: 3

hederacolchiside E: 3

Holothurin: 3

Icogenin: 3

kalopanax saponin A: 3

chikusetsusaponin III: 2

diosponin: 2

macrostemonoside A: 2

maesabalide III: 2

methyl protogracillin: 2

21,23-epoxy-3,20,21-trihydroxydammar-24-ene-3-O-(rhamnopyranosyl-1-2)-(glucopyranosyl-1-3)lyxopyranoside: 1

23-epi-26-deoxyactein: 1

26-O-glucopyranosyl-22-hydroxyfurostane-2,3,26-triol-3-O-glucopyranosyl-1-2-galactopyranoside: 1

3-O-(glucopyranosyl-1-4-cymaropyranosyl-1-4-cymaropyranosyl-1-4-oleandropyranosyl-1-4-cymaropyranosyl)caudatin: 1

3-O-xylopyranosylholosta-7,9(11),22,24-tetraene-3,17-diol: 1

ardipusilloside III: 1

dipsacus saponin B: 1

dipsacus saponin C: 1

gymnemic acid: 1

hederacolchisid A1: 1

hederacolchiside A: 1

jujuboside A: 1

julibroside J28: 1

kaikasaponin III: 1

kalopanax saponin I: 1

loniceroside C: 1

methyl protoneodioscin: 1

mirabilin: 1

niga-ichigoside F1: 1

(23S,24R,25S)-23,24-dihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-glucopyranoside

(23S,25R)-12alpha,17alpha,23-trihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-glucopyranoside

(23S,25R)-14alpha,17alpha,23-trihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(12)-beta-D-glucopyranoside

(25R)-spirost-7-en-2alpha,3beta,5alpha-triol-3-O-(alpha-L-rhamnopyranosyl(1-2)beta-D-galactopyranosyl (1-3)) beta-D-glucopyranoside

1-O-(rhamnopyranosyl-(1-2)-6-O-acetyl-galactopyranosyl)-1,3,22,26-tetrahydroxy-furost-5(6)-en-26-O-glucopyranoside

Experts

1.	Borja-Cabrera, G P: 4 articles (08/2007 - 09/2002)
2.	Palatnik, M: 4 articles (08/2007 - 09/2002)
3.	Sun, Bin: 4 articles (08/2005 - 02/2003)
4.	Yao, Xinsheng: 3 articles (08/2008 - 09/2002)
5.	Lacaille-Dubois, Marie-Aleth: 3 articles (11/2007 - 01/2002)
6.	Santos, F N: 3 articles (08/2007 - 05/2006)
7.	Yin, Hui-jun: 3 articles (04/2007 - 03/2005)
8.	Nah, Seung-Yeol: 3 articles (12/2006 - 10/2005)
9.	Fung, Kwok-Pui: 2 articles (08/2008 - 11/2005)
10.	Koppe, Wolfgang: 2 articles (07/2008 - 03/2007)

Related Diseases

1.	Infection 01/01/2008 - "vannamei immersed in water containing saponin at 2mgL(-1) or less exhibited an immunomodulatory effect, as well as protection against V. alginolyticus infection." 12/01/1991 - "GST-45W gave up to 94% protection against challenge infection when used to vaccinate sheep with saponin as adjuvant. " 02/01/2005 - "The objective of this study was to determine whether a commercially available, saponin-adjuvanted, inactivated bovine respiratory syncytial virus (BRSV) vaccine would protect calves from experimental infection with virulent BRSV. " 07/23/2008 - "Thus, we can conclude that dogs immunized by LBSap and the saponin adjuvant elicited a potential innate-immune activations status compatible with effective control of the resistance to infection by Leishmania and contributing to a better understanding of the innate-immunity events induced by the LBSap vaccine." 12/01/1990 - "Comparison of thick blood smear and saponin haemolysis for the detection of Loa loa and Mansonella perstans infections." Order ALL the reference details at left...
2.	Neoplasms (Cancer) 06/01/2008 - "The review also describes saponins in combination with conventional tumor treatment strategies, which result in improved therapeutic success. " 02/01/2009 - "Saponins as tool for improved targeted tumor therapies." 04/01/2006 - "AIM: To study the anti-tumor bioactive steroid saponins of Paris vietnamensis (Takht.). " 05/01/2004 - "While recent studies have demonstrated a direct effect of soy saponins on cancer cells, alternative mechanisms of cancer prevention by these agents are also discussed. " 01/01/2002 - "In previously published studies, it was shown that certain triterpene saponins (called avicins) from a desert tree, Acacia victoriae, are selectively toxic to tumor cells at very low doses (IC(50): 0.2 microg/mL for Jurkat cells). " Order ALL the reference details at left...
3.	Visceral Leishmaniasis (Kala Azar) 11/01/2007 - "Cellular and humoral immune responses of dogs to a candidate vaccine, composed of Leishmania braziliensis promastigote protein plus saponin as adjuvant, have been investigated as a pre-requisite to understanding the mechanisms of immunogenicity against canine visceral leishmaniasis (CVL). " 08/14/2007 - "In order to assess the immunotherapeutic potential on canine visceral leishmaniasis of the Leishmune vaccine, formulated with an increased adjuvant concentration (1mg of saponin rather than 0.5mg), 24 mongrel dogs were infected with Leishmania (L.) chagasi. " 01/08/2007 - "Assessment of the monoterpene, glycidic and triterpene-moieties' contributions to the adjuvant function of the CP05 saponin of Calliandra pulcherrima Benth during vaccination against experimental visceral leishmaniasis." 05/01/2006 - "Our results confirm in the Riedel de Haen saponin extract the presence of deacylsaponins normonoterpene-deprivated which are non-toxic and capable of inducing a specific and strong immunoprotective response in vaccination against murine visceral leishmaniasis." 08/14/2007 - "Immunotherapy against experimental canine visceral leishmaniasis with the saponin enriched-Leishmune vaccine." Order ALL the reference details at left...
4.	Carcinoma (Carcinomatosis) 08/01/2005 - "[Experimental study of saponins from Tribulus terrestris on renal carcinoma cell line]" 11/01/2005 - "The isolated saponins exhibited antibacterial activities against Gram-positive and Gram-negative bacteria with minimum inhibitory concentration values >100 microg/ml, antifungal activity against all the strains tested with minimum fungicidal concentration values between 25 and 50 microg/ml and inhibited the growth of Hep-2 (human carcinoma of larynx), with IC50 values between 50 microg/ml (compounds 5-7) and 100 microg/ml (compounds 1-4), and Hela (human carcinoma of cervix) cell lines in culture with different IC50 values [74 (compound 7), 98 (compound 5) and 180 microg/ml (compounds 1-4 and 6)]." 08/01/2005 - "OBJECTIVE: To investigate the effect of saponins from Tribulus terrestris (STT) on the renal carcinoma cell (786-0) in vitro, and inhibitory mechanisms. " 11/01/1995 - "Molecular mechanisms of action of the total fraction of saponins from Red Korean Ginseng on the elements of the intracellular signalling system of the cells of ascitic Ehrlich carcinoma (AEC) were studied. " 05/01/1995 - "The effect of saponins on colonic epithelial carcinoma cell (HCT-15) morphology was studied. " Order ALL the reference details at left...
5.	Foot-and-Mouth Disease 01/01/1976 - "Studies about the adjuvant activity of saponin fractions in foot and mouth disease vaccine. " 06/01/1973 - "Studies about the adjuvant activity of saponin fractions in foot and mouth disease vaccine. " 06/01/1967 - "[On several tests of the value of saponin used alone as an adjuvant in the preparation of foot-and-mouth disease vaccine]" 03/01/1965 - "[On the active immunization of swine against foot-and-mouth disease using saponin vaccine]" 09/01/1963 - "[Immunization of pigs against foot-and-mouth disease with tissue culture virus--saponin vaccine]" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Fluorometholone (FML)
2.	Antigens
3.	QS 21 (QS21)
4.	Saponins
5.	Vaccines
6.	fucose-binding lectin
7.	Immunologic Adjuvants (Immunologic Adjuvant)
8.	panaxatriol
9.	protopanaxadiol
10.	Glycoproteins (Glycoprotein)

Related Therapies and Procedures

1.	Ligation
2.	Heterologous Transplantation (Xenotransplantation)
3.	Oral Administration
4.	Lasers (Laser)
5.	Chinese Traditional Medicine (Traditional Chinese Medicine)

Best Treatments:
Research Summary Report
on Infection

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 14726 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>