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Panax quinquefolium saponin

has protective effects on oxidative damage of cultured rat cardiac cells

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - Panax quinquefolium saponin: 7

Experts

1.	Liu, Mi: 3 articles (09/2015 - 10/2013)
2.	Liu, Xiu-Hua: 3 articles (09/2015 - 10/2013)
3.	Shi, Da-Zhuo: 3 articles (09/2015 - 10/2013)
4.	Tao, Tian-Qi: 2 articles (09/2015 - 01/2014)
5.	Wang, Xiao-Reng: 2 articles (09/2015 - 10/2013)
6.	Song, Dan-Dan: 2 articles (01/2014 - 10/2013)
7.	Li, Peng: 1 article (08/2021)
8.	Liu, Jian-Gang: 1 article (08/2021)
9.	Wang, Cheng-Long: 1 article (08/2021)
10.	Yu, Yong-Hui: 1 article (08/2021)

Related Diseases

1.	Hypoxia (Hypoxemia) 08/01/2021 - "To investigate the effects and underlying mechanisms of Panax quinquefolium saponin (PQS) on energy deficiency in hypoxia-reperfusion (H/R) induced cardiomyocytes. " 08/01/2021 - "Panax quinquefolium saponin Optimizes Energy Homeostasis by Modulating AMPK-Activated Metabolic Pathways in Hypoxia-Reperfusion Induced Cardiomyocytes." 10/01/2013 - "Panax quinquefolium saponin (PQS) alleviates hypoxia-reoxygenation injury of cardiomyocytes in vitro by inhibiting excessive endoplasmic reticulum stress (ERS)-related apoptosis. " 09/01/2015 - "Endoplasmic reticulum (ER) stress-related apoptosis is involved in the pathophysiology of many cardiovascular diseases, and Panax quinquefolium saponin (PQS) is able to inhibit excessive ER stress-related apoptosis of cardiomyocytes following hypoxia/reoxygenation and myocardial infarction. " 05/01/2015 - "To explore the effects of Panax Quinquefolium Saponin (PQS) on phosphatidylinositol 3-kinase/serine threonine kinase (PI3K/Akt) pathway of neonatal rat myocardial cells subjected to hypoxia. "
2.	Myocardial Infarction 03/15/2019 - "Panax quinquefolium saponin (PQS) improves ventricular remodeling after acute myocardial infarction by alleviating endoplasmic reticulum stress and Ca2+overload. " 10/01/2013 - "Panax quinquefolium saponin attenuates ventricular remodeling after acute myocardial infarction by inhibiting chop-mediated apoptosis." 09/01/2015 - "Endoplasmic reticulum (ER) stress-related apoptosis is involved in the pathophysiology of many cardiovascular diseases, and Panax quinquefolium saponin (PQS) is able to inhibit excessive ER stress-related apoptosis of cardiomyocytes following hypoxia/reoxygenation and myocardial infarction. "
3.	Ventricular Remodeling 03/15/2019 - "Panax quinquefolium saponin (PQS) improves ventricular remodeling after acute myocardial infarction by alleviating endoplasmic reticulum stress and Ca2+overload. " 10/01/2013 - "Panax quinquefolium saponin attenuates ventricular remodeling after acute myocardial infarction by inhibiting chop-mediated apoptosis."
4.	Osteoarthritis 01/01/2018 - "Panax quinquefolium saponin inhibits endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and attenuates the progression of osteoarthritis in rat."
5.	Ischemia 01/01/2014 - "Panax quinquefolium saponin attenuates cardiomyocyte apoptosis and opening of the mitochondrial permeability transition pore in a rat model of ischemia/reperfusion."

Related Drugs and Biologics

1.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
2.	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)
3.	Mitochondrial Permeability Transition Pore