Carcinoma (Carcinomatosis)

92356  relevant articles (2959 outcomes, 11590 trials/studies) found for this Disease

Carcinomatosis; Carcinomas; Epithelioma; Epithelial Tumors, Malignant; Malignant Epithelial Neoplasms; Neoplasms, Malignant Epithelial; Anaplastic Carcinoma; Anaplastic Carcinomas; Carcinoma, Spindle Cell; Carcinomas, Anaplastic; Carcinomas, Spindle-Cell; Carcinomas, Undifferentiated; Carcinomatoses; Epithelial Neoplasm, Malignant; Epithelial Tumor, Malignant; Epitheliomas; Malignant Epithelial Neoplasm; Malignant Epithelial Tumor; Malignant Epithelial Tumors; Neoplasm, Malignant Epithelial; Spindle-Cell Carcinoma; Spindle-Cell Carcinomas; Tumor, Malignant Epithelial; Tumors, Malignant Epithelial; Undifferentiated Carcinoma; Undifferentiated Carcinomas; Carcinoma, Anaplastic; Carcinoma, Spindle-Cell; Carcinoma, Undifferentiated; Epithelial Neoplasms, Malignant

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Neoplasm Metastasis (Metastasis)
3.	Melanoma (Melanoma, Malignant)
4.	Carcinoma (Carcinomatosis)
5.	Breast Neoplasms (Breast Cancer)

Experts

1.	Chan, Anthony T C: 33 articles (08/2008 - 08/2002)
2.	Davidson, Ben: 29 articles (04/2008 - 01/2002)
3.	Agarwal, Rajesh: 26 articles (09/2008 - 03/2002)
4.	Sham, Jonathan S T: 23 articles (07/2008 - 04/2002)
5.	Hortobagyi, Gabriel N: 22 articles (06/2007 - 05/2002)
6.	Zeng, Yi-Xin: 21 articles (11/2008 - 02/2002)
7.	Agarwal, Chapla: 21 articles (09/2008 - 03/2002)
8.	Moriya, Takuya: 20 articles (07/2008 - 01/2002)
9.	Nesland, Jahn M: 20 articles (01/2008 - 01/2002)
10.	Nesland, J M: 20 articles (01/2004 - 03/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Carcinoma:

1.	Cisplatin (Platino)FDA LinkGeneric 01/01/2003 - "We report a patient with highly advanced gastric carcinoma who was treated successfully with a new combination chemoradiotherapy using S-1 and cisplatin (CDDP). " 12/15/2003 - "Intercalation is the preferred binding mode for 2, whereas both intercalation and minor-groove binding are observed for 1. Complex 1 is cytotoxic against a number of carcinoma cell lines, including KB-3-1, CNE-3, and HepG2, and remains potent against multidrug- or cisplatin-resistant KB-V-1 and CNE1 cell lines, for which the resistance ratios are 1.6 and 1.5, respectively. " 11/15/1993 - "CONCLUSION: The combination of weekly cisplatin and radiotherapy appears to be a very effective regimen for patients with locally advanced carcinoma of the cervix, but resulted in a relatively high frequency of late gastrointestinal complications." 02/01/1991 - "Ovarian carcinoma demonstrates a steep dose-response curve for cisplatin, but even very small levels of acquired resistance at the cellular level are sufficient to block the efficacy of intravenous (IV) cisplatin. " 06/01/1996 - "Phase I/II combined modality studies established the efficacy of concurrent high-dose cisplatin and radiotherapy in the treatment of advanced disease and provided the basis for further testing in Phase III trials for nasopharyngeal carcinoma, larynx preservation, and high-risk advanced operable disease. " Order ALL the reference details at left...
2.	Fluorouracil (Carac)FDA LinkGeneric 11/01/2001 - "BACKGROUND AND OBJECTIVES: The combination of 5-fluorouracil and radiotherapy is thought to be the most effective treatment for locally unresectable pancreatic carcinoma. " 04/15/1983 - "The authors concluded that three courses of CDDP and 5-FU is a highly effective and safe adjuvant treatment in patients with advanced carcinoma of the head and neck." 07/01/2001 - "CONCLUSION: Adjuvant radiochemotherapy, WAI, and concomitant 5-FU, is a feasible and a fairly well-tolerated treatment for patients with locally advanced (involvement of the lymph nodes or serosa) gastric carcinoma who undergo complete resection. " 01/01/1989 - "The administration of systemically and intraperitoneally infused 5-fluorouracil (5-FU) in patients with ovarial carcinoma did not shown in any patient a complete or partial remission, but showed severe side effects. " 10/05/2005 - "The killing ability against target cells previously exposed to sublethal doses of 5-FU was statistically significantly greater than against untreated target cells (43.5% versus 26.5% at 25/1 effector to target ratio [Difference {diff} = 17.0]; 95% confidence interval [CI] = 12.6 to 20.4) for MDA-MB-231 breast carcinoma cells and 73.5 versus 48.5 (diff = 25.0; 95% CI = 16.2 to 33.8) for the SW-1463 colon carcinoma cells. " Order ALL the reference details at left...
3.	Paclitaxel (Taxol)FDA LinkGeneric 10/15/2001 - "Treatment of ovarian carcinomas with the antimitotic antitumor drug paclitaxel is highly efficacious. " 04/01/2006 - "CONCLUSION: The significant efficacy of (90)Y-hu3S193 and paclitaxel CMRIT at low radiation doses in this model of breast carcinoma indicates its therapeutic potential and warrants further investigation into this promising therapeutic approach." 02/01/2002 - "NMP-1 and HEY models have significant value in establishing the efficacy of candidate agents, which might address Taxol-resistant human ovarian carcinoma. " 07/01/2006 - "In particular, paclitaxel has been demonstrated to be effective for the treatment of ovarian, breast, and nonsmall cell lung carcinomas. " 11/01/2003 - "Intraperitoneal treatment using taxol is effective for experimental peritoneal carcinomatosis in a rat model." Order ALL the reference details at left...
4.	Doxorubicin (Adriamycin)FDA LinkGeneric 01/25/2002 - "We therefore investigated the physical properties of liposomal doxorubicin (DOX) and found it to be most effective when administered intraperitoneally for carcinoma in the abdominal cavity. " 08/20/1989 - "It was concluded that this combination therapy is beneficial in patients with advanced gastric carcinoma because it showed measurable clinical effectiveness with less toxicity than FAM therapy (a combination of 5-FU, Doxorubicin and MMC)." 07/01/1991 - "Doxorubicin has been shown to be more effective against MGH-U1 bladder carcinoma cells grown in monolayer than spheroid. " 09/15/1983 - "If an effective systemic treatment regimen can be devised for anaplastic carcinoma of the thyroid, the present Adriamycin and hyperfractionated radiation therapy may be capable of achieving improved survival time." 10/01/1991 - "Previously established animal models of invasive transitional cell bladder carcinoma and continuous infusion intravesical drug delivery were combined to evaluate the urothelial toxicity and antineoplastic efficacy of continuous intravesical infusion doxorubicin (DOX). " Order ALL the reference details at left...
5.	AntigensIBA 11/01/1997 - "Carcinoma of the prostate in the United States has increased dramatically in the last few years due to improved detection methods including prostatic specific antigen testing and transrectal ultrasound. " 07/01/2002 - "Against tumor cell lines with varying levels of BR96 expression, both conjugates showed potent, antigen-specific cytotoxic activity, suggesting that they will be effective in delivering DOX selectively to antigen-expressing carcinomas." 09/01/2000 - "To optimize our immunohistochemical evaluation of breast carcinomas, we compared the efficacy of these methods of antigen recovery for several important antigens. " 01/01/1994 - "The antigen phenotype of the carcinoma cell will play an important role in the efficacy of the MAbs. " 01/01/1991 - "The antigen phenotype of the carcinoma cell will play an important role in the efficacy of the MoAbs. " Order ALL the reference details at left...
6.	HormonesIBA 04/01/1982 - " The prognosis for breast carcinoma developing in hormone users is improved, most likely because of an earlier detection. " 01/01/1994 - "The unavailability of effective treatment for metastatic hormone-refractory and clinically localized but pathologically unfavorable prostatic carcinoma warrants trial of new and promising treatments. " 01/01/1992 - "The unavailability of effective treatment of metastatic hormone refractory prostatic carcinoma warrants trials of new and promising treatments. " 01/01/2006 - "Long-term hormone therapy and radiation is cost-effective for patients with locally advanced prostate carcinoma." 02/01/2000 - "BACKGROUND: There is currently no effective treatment for recurrent hormone refractory carcinomas of the prostate gland. " Order ALL the reference details at left...
7.	PlatinumIBA 04/01/2003 - "OBJECTIVE: To estimate the antitumor efficacy of dolastatin-10 in patients with measurable recurrences of platinum-sensitive ovarian carcinoma and to determine the nature and degree of toxicity of dolastatin-10 in these patients. " 09/01/2009 - "In this study, platinum-based chemoradiotherapy provided good local control for oropharyngeal carcinoma. " 01/01/2009 - "In this study, we aimed to search for genes or genomic regions involved in platinum resistance in ovarian carcinoma. " 05/01/2008 - "PATIENTS AND METHODS: Women with recurrent or persistent epithelial ovarian or primary peritoneal carcinoma who were platinum-resistant/refractory (progression-free interval <12 months since platinum) were eligible for trial entry if they had measurable disease, a good performance status, and good overall organ function. " 01/01/2008 - "For metastatic and locally advanced esophageal and gastric carcinoma, the results of clinical trials over recent years have led to the following concrete changes: the importance of platinum has been confirmed. " Order ALL the reference details at left...
8.	Carboplatin (JM8)FDA LinkGeneric 06/01/2008 - "CONCLUSION: Continuous IA CBDCA and concurrent radiation therapy can be delivered safely with good efficacy for locally advanced carcinoma of the tongue." 11/15/2000 - "CONCLUSIONS: Superselective continuous intraarterial carboplatin and concurrent radiation therapy can be delivered safely with good efficacy for locally advanced carcinomas of the tongue and base of the tongue. " 03/01/2007 - "The current case suggests that combination CBDCA plus weekly PTX is effective against advanced clear cell carcinoma of the endometrium." 09/01/1996 - "(2) The efficacy of ip administration of carboplatin-loaded alpha-TCP (alpha-TCP-CBDCA) was examined using a Donryu rat model with AH130 abdominal carcinomatosis. " 04/15/2006 - "These studies suggest that AAV-mediated gene therapy of P125A-endostatin in combination with carboplatin is a useful method to inhibit peritoneal dissemination of ovarian carcinoma." Order ALL the reference details at left...
9.	DNA (Deoxyribonucleic Acid)IBA 08/15/2003 - "Rapid clearance of plasma Epstein-Barr virus DNA after surgical treatment of nasopharyngeal carcinoma." 09/01/1995 - "CONCLUSIONS: The prevalence of human papillomavirus DNA is significantly greater in carcinoma of the penis than in control tissue. " 12/01/1976 - "The high rate of false negative and false positive results (11.4% and 29.7%, respectively) argues against using flow-through photometric nuclear DNA determination for the diagnosis of prostate carcinoma." 08/01/2008 - "Our findings suggested that HPV genotyping for the eight oncogenic types might be useful to improve the efficacy of HPV DNA testing for predicting CIN 2/3/carcinoma in women with mildly abnormal Pap results, which may lead to personalized clinical management with improved patient compliance for follow-up." 01/01/2005 - "The protective efficacy of xenogeneic vaccination with DNA encoding the HER2 oncogene was evaluated in BALB/c mice transgenic for the transforming form of the neu oncogene, which spontaneously develops carcinomas in all mammary glands. " Order ALL the reference details at left...
10.	Estrogens (Estrogen)FDA Link 02/15/1988 - "These characteristics are reflected in the marked efficacy with which it affects growth of estrogen-dependent 7,12-dimethylbenz(a)antracene-induced mammary carcinomas in intact female Sprague-Dawley rats. " 07/01/1975 - "In darkness the percentage of the take of the carcinoma proved to be less, and also the growth of the RMC-1 was delayed; there was also a marked increase in the efficacy of estrogen-therapy of mammary carcinoma. " 12/15/1980 - "This study corroborates previous reports which suggested the efficacy of estrogen receptor (ER) analysis in predicting responses of patients with metastatic mammary carcinoma to hormonal therapeutic manipulation. " 06/01/1980 - "Relationships of S-phase fraction of breast carcinoma in relapse to duration of remission, estrogen receptor content, therapeutic responsiveness, and duration of survival." 01/01/1991 - "The promising results obtained in a pilot study of parenteral estrogen therapy in patients with prostatic carcinoma await confirmation in a randomised study, but where treatment with estrogen is considered for these patients, it may be that parenteral administration would be preferable." Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 10/01/2006 - "Chemotherapy may be more effective in highly proliferative ovarian carcinomas--a translational research subprotocol of a prospective randomized phase III study (AGO-OVAR 3 protocol)." 04/01/1999 - "CONCLUSIONS: The results of the current study indicate that a weekly PFB/ME neoadjuvant chemotherapy regimen is highly effective for the treatment of patients with oral carcinoma. " 08/01/1998 - "In small controlled trials, systemic chemotherapy has improved survival and quality of life of patients with advanced gastric carcinoma when compared with best supportive care. " 06/01/1993 - "However, current studies with conventional chemotherapy, radiation and surgery are likely to impart at best a modest to moderate improvement in the treatment of esophageal carcinoma. " 07/01/2004 - "PURPOSE: Radiotherapy -/+ chemotherapy is the first-line treatment for carcinoma of the anal canal in most oncology institutions. " Order ALL the reference details at left...
2.	Heterologous Transplantation (Xenotransplantation) 02/01/1993 - "Furthermore, treatment with a total dose of only 0.44 mg of ICR62 was found to induce complete remission of xenografts of the breast carcinoma MDA-MB 468, but ICR16 was less effective at this dose of antibody and only 4/8 tumours regressed completely. " 08/19/2002 - "Of the analogues examined, ER-35745, a 6-amino-3-pyridinesulfonamide derivative, demonstrated significant oral efficacy against the HCT116 human colon carcinoma xenograft in nude mice." 02/01/2001 - "In an attempt to investigate the pharmacological basis of the improvement of therapeutic efficacy of the analogue, a comparative pharmacokinetic (tissue and tumour distribution) and pharmacodynamic (antitumoral activity and ability to induce apoptosis) study of MEN10755 and DXR was performed in athymic nude mice bearing a human ovarian carcinoma xenograft (A2780). " 04/01/2004 - "DF3gamma34.5 was effective against carcinoma xenografts in nude mice. " 01/01/2001 - "A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts." Order ALL the reference details at left...
3.	Combination Drug Therapy (Combination Chemotherapy) 02/01/1994 - "Because of the rarity of the primary fallopian tube carcinoma, optimal primary therapy is still not well defined, and there is little information available regarding the efficacy of combination chemotherapy in advanced disease. " 08/01/1986 - "Complete remission with combination chemotherapy in metastatic breast carcinoma." 02/01/1984 - "Ventilation/perfusion relations in patients with small cell anaplastic carcinoma of the lung, obtaining complete remission during combination chemotherapy." 07/01/1980 - "By polychemotherapy we achieved in 13 metastatasized carcinomas of the mamma 4 partial and one complete remission, in 15 inoperable lung tumours we achieved four times a standstill of the growth and a complete remission over two years, whereas the tumours of the gastro-intestinal tract could be influenced less clearly. " 03/01/1983 - "High-dose combination chemotherapy with ABMT seemed quite effective in advanced breast carcinoma and a similar approach in adjuvant setting has also been suggested." Order ALL the reference details at left...
4.	Lymph Node Excision (Lymph Node Dissection) 01/01/2006 - "The present study aimed to clarify the efficacy of extensive surgery, including pancreas head resection, for more complete lymphadenectomy in the treatment of gallbladder carcinoma. " 12/01/1991 - "Recent studies suggest an improved survival in patients who undergo radical lymph node dissection for the curative treatment of gastric carcinoma. " 07/01/2002 - "CONCLUSIONS: Hepatopancreatoduodenectomy with wide lymph node dissection is an effective treatment for the selected patients with locally advanced gallbladder carcinoma with until pN2 disease, if curative resection is potentially feasible. " 12/01/2000 - "The results of this study indicate that a significant number of patients can be cured of esophageal carcinoma by extensive resection along with extended lymph node dissection even when the disease metastasizes to distant nodes." 09/01/2008 - "However, survival in patients with intermediate high-risk carcinomas who underwent lymphadenectomy (LNE) was not significantly improved as compared to those who did not. " Order ALL the reference details at left...
5.	Brachytherapy 03/01/2002 - "The purpose of this study was to evaluate the treatment results of preoperative brachytherapy and the prognostic value of pathologic complete remission after preoperative intracavitary irradiation in patients with stage Ib and IIa cervical carcinoma in relation to recurrence rate and survival. " 05/01/2005 - "CONCLUSION: The results of our study indicate that HDR brachytherapy at 9 Gy/fraction is both safe and effective in the management of carcinoma of the cervix, with good local control and a minimum of normal tissue toxicity." 12/01/2004 - "To date none of the studies examined the feasibility and efficacy of interstitial high-dose-rate (HDR) brachytherapy in the treatment of carcinoma of the tongue base. " 09/01/2007 - "PURPOSE: To investigate the efficacy of dose calculations at the computed tomography (CT)-based rectal point (CTRP) as a predictive factor for late rectal complications in patients with cervical carcinoma who were treated with a combination of high-dose-rate intracavitary brachytherapy and external beam radiotherapy. " 12/01/1994 - "In bulky (Stage I-II) carcinoma of the cervix treated by initial open teletherapy (without shielding), there was a statistically significant reduction in the prescribed brachytherapy dose with increasing dose rate. " Order ALL the reference details at left...