buddlejasaponin

isolated from Buddleja madagascariensis; structure given in first source

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

1.	Iron Overload 01/30/2024 - "Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease."
2.	Parkinson Disease (Parkinson's Disease) 01/30/2024 - "Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease."
3.	Mouth Neoplasms (Oral Cancer) 12/01/2022 - "Anticancer effect of buddlejasaponin IV and buddlejasaponin IVa from Clinopodium umbrosum on oral cancer cells (HN-5)." 12/01/2022 - "umbrosum aerial parts were solvent extracted and extracts were fractionated via various chromatographic techniques, so as to obtain two pure saponins, buddlejasaponin IVa and buddlejasaponin IV. The cytotoxicity activity of the extracts and the two pure compounds on oral cancer cells (HN-5) and human umbilical vein endothelial cells (HUVECs) were investigated by 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide (MTT) method. "
4.	Infections 09/01/2022 - "The results show that Buddlejasaponin IVb can effectively relieve the clinical symptoms and intestinal damage caused by PEDV infection in pigs. "