actein

04/01/2017 - "Actein ameliorates hepatobiliary cancer through stemness and p53 signaling regulation."
12/01/2017 - "In vivo, U937-bearing tumor growth was suppressed by actein, which was related to ROCK1 suppression, AKT dephosphorylation and apoptosis induction. "
04/01/2017 - "However, the effects of actein treatment on liver injury, tending to cancer, have little to be known. "
12/01/2013 - "To develop actein to prevent and treat cancer, we examined the primary targets and combinations with chemotherapy agents, as well as the ability of nanoparticles to enhance the activity. "
01/01/2020 - "The in vivo effect of actein on tumor growth and metastasis in MDA-MB-361 tumor-bearing mice as well as the anti-brain metastasis in tail vein injection mice model were also investigated. "

01/01/2018 - "Liver inflammation and fibrosis triggered by high fat diet were decreased for actein administration. "
04/01/2017 - "DEN caused steatohepatitis supported by fibrosis and inflammation, which were ameliorated for actein administration. "
01/01/2018 - "Actein ameliorates hepatic steatosis and fibrosis in high fat diet-induced NAFLD by regulation of insulin and leptin resistant."

01/01/2018 - "Actein ameliorates hepatic steatosis and fibrosis in high fat diet-induced NAFLD by regulation of insulin and leptin resistant."

11/01/2007 - "This study seeks to identify genes altered in human breast cancer cells by treatment with actein, using gene expression analysis. "
02/01/2004 - "Further studies are in progress to identify the mechanisms by which actein and related compounds present in black cohosh inhibit growth of human breast cancer cells."
01/01/2020 - "All these findings strongly suggested that actein is a potential anti-metastatic agent for HER2-positive breast cancer."
01/01/2020 - "Our results showed that actein inhibited HER2-positive breast cancer cells viability, proliferation and migration. "
01/01/2018 - "These findings shed light for the development of actein as novel anti-migration natural compound for advanced breast cancer."

04/01/2017 - "Thus, the study is conducted to explore the role of actein in early liver cancer. "
04/01/2017 - "Taken together, DEN promoted liver cancer progression, which was ameliorated by actein, supplying a potential therapeutic strategy for liver cancer in future."
04/01/2017 - "Diethylnitrosamine (DEN) was used to induce liver cancer in mice followed by actein treatment at different concentrations. "
06/01/2009 - "Consistent with actein's statin- and stress-associated responses, actein reduced free fatty acid and cholesterol content in the liver by 0.6-fold at 24 h and inhibited the growth of human HepG2 liver cancer cells. "