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timosaponin B-II

from Anemarrhenae asphodeloides; improved memory and learning dysfunction induced by cerebral ischemia in rats; structure in first source

Networked: 9 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - timosaponin B-II: 9
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - timosaponin B-II: 9

Experts

1.	Cui, Ling-Ling: 2 articles (01/2016 - 01/2015)
2.	Ji, De: 2 articles (01/2016 - 01/2015)
3.	Li, Fei: 2 articles (01/2016 - 01/2015)
4.	Ruan, Shi-Xia: 2 articles (01/2016 - 01/2015)
5.	Yang, Zhong-Lin: 2 articles (01/2016 - 01/2015)
6.	Yuan, Yong-Liang: 2 articles (01/2016 - 01/2015)
7.	Zhang, Chun-Feng: 2 articles (01/2016 - 01/2015)
8.	Gu, Xiaochuan: 1 article (01/2022)
9.	Jin, Wenming: 1 article (01/2022)
10.	Li, Han: 1 article (01/2022)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2016 - "Timosaponin B-II Ameliorates Palmitate-Induced Insulin Resistance and Inflammation via IRS-1/PI3K/Akt and IKK/NF-[Formula: see text]B Pathways." 01/01/2016 - "This study aimed to investigate the effect of timosaponin B-II (TB-II) on palmitate (PA)-induced insulin resistance and inflammation in HepG2 cells, and probe the potential mechanisms. " 01/01/2022 - "Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro."
2.	Insulin Resistance 01/01/2016 - "Timosaponin B-II Ameliorates Palmitate-Induced Insulin Resistance and Inflammation via IRS-1/PI3K/Akt and IKK/NF-[Formula: see text]B Pathways." 01/01/2016 - "This study aimed to investigate the effect of timosaponin B-II (TB-II) on palmitate (PA)-induced insulin resistance and inflammation in HepG2 cells, and probe the potential mechanisms. "
3.	Diabetic Nephropathies (Diabetic Nephropathy) 01/01/2015 - "Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice."
4.	Acute Lung Injury 01/01/2015 - "Timosaponin B-II (TB), a main bioactive compound in Anemarrhena asphodeloides Bunge, has various kinds of pharmacological activities, the present study aimed to investigate the protective role of TB on lipopolysaccharide (LPS)-induced acute lung injury (ALI). "
5.	Myocardial Infarction 10/05/2015 - "The aim of the present study was to investigate the cardioprotective effects of Timosaponin B II (TB), a main bioactive constituent from Anemarrhenae asphodeloides Bge, on an isoproterenol (ISO)-induced myocardial infarction model in rats and explore its underlying mechanisms. " 10/05/2015 - "Cardioprotective effects of timosaponin B II from Anemarrhenae asphodeloides Bge on isoproterenol-induced myocardial infarction in rats."

Related Drugs and Biologics

1.	Palmitates
2.	Alloxan
3.	Lipopolysaccharides
4.	Isoproterenol (Isoprenaline)
5.	Mitogen-Activated Protein Kinases
6.	Solutions
7.	icariin
8.	ferulic acid (sodium ferulate)

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)