Abstract | PURPOSE OF REVIEW: Traditionally, lupus nephritis has been considered an autoimmune disorder of unknown origin and a complex pathophysiology, but in recent years, its pathogenesis has been unraveled. RECENT FINDINGS: SUMMARY: Eventually, a better understanding of lupus nephritis pathogenesis will allow the identification of therapeutic targets that will prove effective not only in animal models but also in randomized clinical trials.
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Authors | Georg Lorenz, Jyaysi Desai, Hans-Joachim Anders |
Journal | Current opinion in nephrology and hypertension
(Curr Opin Nephrol Hypertens)
Vol. 23
Issue 3
Pg. 211-7
(May 2014)
ISSN: 1473-6543 [Electronic] England |
PMID | 24662982
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Anti-Inflammatory Agents
- Inflammation Mediators
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Topics |
- Animals
- Anti-Inflammatory Agents
(therapeutic use)
- Autoimmunity
(drug effects)
- Humans
- Inflammation Mediators
(metabolism)
- Kidney
(drug effects, immunology, metabolism, pathology)
- Lupus Nephritis
(drug therapy, immunology, metabolism, pathology)
- Risk Factors
- Signal Transduction
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