Antiviral Agents (Antivirals)

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Also Known As:
Antivirals; Antiviral Drugs; Agents, Antiviral; Drugs, Antiviral
Networked: 3949 relevant articles (410 outcomes, 339 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. De Clercq, Erik: 25 articles (11/2015 - 08/2002)
2. Neyts, Johan: 18 articles (12/2015 - 08/2002)
3. Hayden, Frederick G: 14 articles (03/2015 - 01/2004)
4. Zeuzem, Stefan: 13 articles (07/2015 - 04/2007)
5. Soriano, Vincent: 13 articles (03/2015 - 04/2006)
6. Hurt, Aeron C: 13 articles (01/2015 - 06/2007)
7. Smee, Donald F: 13 articles (01/2015 - 07/2002)
8. Marcellin, Patrick: 12 articles (07/2015 - 10/2006)
9. Barreiro, Pablo: 12 articles (03/2015 - 05/2008)
10. Monto, Arnold S: 12 articles (12/2014 - 05/2003)

Related Diseases

1. Infection
2. Human Influenza (Influenza)
01/01/2015 - "The ferret is a suitable small animal model for preclinical evaluation of efficacy of antiviral drugs against various influenza strains, including highly pathogenic H5N1 viruses. "
12/01/2014 - "Indeed, although vaccination is the most powerful means of mitigating the effects of influenza epidemics, antiviral drugs can be very useful, particularly in delaying the spread of new pandemic viruses, thereby enabling manufacturers to prepare large quantities of pandemic vaccine. "
11/01/2013 - "The goals of the meeting were to improve pandemic planning in the region from lessons learned during the 2009 pandemic, particularly with regard to the safety and efficacy of antiviral use; gain a better understanding of the therapeutic use of antivirals in seasonal influenza; review and analyse the official influenza control policies of Asia-Pacific countries and evidence gaps to support policy development; and to establish collaborative relationships to promote best practices in the use of antivirals for the treatment of influenza. "
02/04/2013 - "These promising results demonstrate that the oral peptide transporter-mediated prodrug strategy has enormous promise for improving the oral mucosal cell membrane permeability of polar, poorly absorbed antiviral agents and treating influenza via the oral route of administration."
06/01/2007 - "The availability of isolation facilities, the stockpiling of antiviral agents and effective and safe vaccination will be extremely important in minimising the damage of a new influenza pandemic."
3. Hepatitis C
4. Hepatitis B
5. Chronic Hepatitis B

Related Drugs and Biologics

1. Interferons
2. Vaccines
3. Ribavirin (Virazole)
4. Neuraminidase (Sialidase)
5. Acyclovir (Aciclovir)
6. Amantadine (Aman)
7. Rimantadine
8. Lamivudine (3TC)
9. Zanamivir (Relenza)
10. Interferon-alpha (Interferon Alfa)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Transplants (Transplant)
3. Therapeutics
4. Plasma Exchange
5. Immunotherapy