Abstract | BACKGROUND: METHODS: RESULTS: There were significant differences in mean leptin values in the four adipokines from the four different groups (P < 0.001; comparison of the variation between different groups was analyzed by variance analysis). Compared to controls (using multiple comparison two-way Dunnett t test), only the leptin level showed significant differences in the four adipokines from the four different groups at the same time (P < 0.001). The association analysis between the different adipokines and M or M/I values also showed that only leptin negatively correlated with M (r = -0.64, P < 0.001) or M/I values (r = -0.56, P < 0.001); there was no relationship between the other three adipokines and M or M/I values. CONCLUSION: Only leptin was associated with M or M/I values. Therefore, leptin might be one of the predictive factors of the degree of insulin resistance and risk of the accompanying disease.
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Authors | Tao Yuan, Wei-gang Zhao, Qi Sun, Yong Fu, Ying-yue Dong, Ya-xiu Dong, Guo-hua Yang, Heng Wang |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 123
Issue 15
Pg. 2018-22
(Aug 05 2010)
ISSN: 2542-5641 [Electronic] China |
PMID | 20819535
(Publication Type: Journal Article)
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Chemical References |
- Adipokines
- Adiponectin
- Leptin
- Resistin
- Tumor Necrosis Factor-alpha
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Topics |
- Adipokines
(blood)
- Adiponectin
(blood)
- Asian People
- Diabetes Mellitus, Type 1
(blood)
- Diabetes Mellitus, Type 2
(blood)
- Glucose Clamp Technique
- Humans
- Insulin Resistance
(physiology)
- Leptin
(blood)
- Obesity
(blood)
- Resistin
(blood)
- Tumor Necrosis Factor-alpha
(blood)
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