Abstract | PURPOSE: EXPERIMENTAL DESIGN: RESULTS:
DbpA expression was associated with the advanced stages of hepatocellular carcinoma, and the cases with the nuclear dbpA expression had a poor prognosis. DbpA contributed more significantly to this association than YB-1. Furthermore, the T-to-G transversion in the dbpA promoter region was related to the nuclear localization of dbpA. CONCLUSION:
|
Authors | Mahmut Yasen, Kazunori Kajino, Sayaka Kano, Hiroshi Tobita, Junji Yamamoto, Takeshi Uchiumi, Shigeyuki Kon, Masahiro Maeda, Gulanbar Obulhasim, Shigeki Arii, Okio Hino |
Journal | Clinical cancer research : an official journal of the American Association for Cancer Research
(Clin Cancer Res)
Vol. 11
Issue 20
Pg. 7354-61
(Oct 15 2005)
ISSN: 1078-0432 [Print] United States |
PMID | 16243807
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Antibodies, Monoclonal
- Biomarkers, Tumor
- DNA-Binding Proteins
- Y-Box-Binding Protein 1
- DNA
|
Topics |
- Antibodies, Monoclonal
(immunology)
- Antibody Specificity
- Biomarkers, Tumor
(analysis)
- Carcinoma, Hepatocellular
(genetics, metabolism, pathology)
- Cell Nucleus
- DNA
(chemistry, genetics)
- DNA Mutational Analysis
- DNA-Binding Proteins
(analysis, genetics, immunology)
- Immunohistochemistry
- Liver Neoplasms
(genetics, metabolism, pathology)
- Point Mutation
- Prognosis
- Promoter Regions, Genetic
(genetics)
- Survival Analysis
- Up-Regulation
- Y-Box-Binding Protein 1
(analysis, genetics, immunology)
|