Enclomiphene (Enclomifene)

The trans or (E)-isomer of clomiphene.

Also Known As:

Enclomifene; (E)-2-(p-(2-Chloro-1,2-Diphenylvinyl)phenoxy)triethylamine; (E)-2-(p-(2-Chloro-1,2-Diphenylvinyl)phenoxy)triethylamine Citrate; Androxal; En-Clomiphene; Enclomiphen; Enclomiphene Citrate; trans-Clomiphene; trans-Clomiphene Citrate; Citrate, Enclomiphene; Citrate, trans-Clomiphene; trans Clomiphene; trans Clomiphene Citrate

Networked: 24 relevant articles (3 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Clomiphene: 2111
        Enclomiphene: 24

Experts

1.	Hsu, Kuang: 3 articles (01/2017 - 07/2013)
2.	Kim, Edward D: 2 articles (01/2019 - 04/2016)
3.	McCullough, Andrew: 2 articles (01/2017 - 04/2016)
4.	Kaminetsky, Jed: 2 articles (04/2016 - 06/2013)
5.	Fontenot, Gregory K: 2 articles (09/2014 - 07/2013)
6.	Wiehle, Ronald D: 2 articles (09/2014 - 06/2013)
7.	Wike, Jenny: 2 articles (09/2014 - 07/2013)
8.	Achua, Justin K: 1 article (12/2020)
9.	Frech, Fabio S: 1 article (12/2020)
10.	Ramasamy, Ranjith: 1 article (12/2020)

Related Diseases

1.	Obesity 02/01/2009 - "Enclomiphene demonstrates promise in the management of secondary hypogonadism associated with obesity, metabolic syndrome and, possibly, infertility, and should undergo placebo-controlled, randomized clinical trials for these indications." 01/01/2023 - "Seven studies met the inclusion criteria providing information on 292 men with obesity-related functional androgen deficiency treated with clomiphene citrate (12.5-50 mg daily) or enclomiphene citrate (12.5-25 mg daily) for 1.5-4 months. " 01/01/2023 - "Treatment with clomiphene citrate and enclomiphene citrate may be an effective and safe alternative to testosterone replacement therapy in men with obesity-related functional androgen deficiency. "
2.	Hypogonadism (Hypergonadotropic Hypogonadism) 01/01/2019 - "Enclomiphene citrate: A treatment that maintains fertility in men with secondary hypogonadism." 08/01/2016 - "Enclomiphene citrate for the treatment of secondary male hypogonadism." 03/01/2016 - "Reproductive endocrinology: Oral enclomiphene citrate in obese men with hypogonadism." 09/01/2014 - "Enclomiphene citrate reverses the two hallmarks of secondary hypogonadism, namely, low serum total T and low or inappropriately normal LH while preserving sperm production. " 09/01/2014 - "Treatment with enclomiphene citrate resulted in increased morning serum T, E2, and LH levels similar to those obtained with a topical T gel in men with secondary hypogonadism. "
3.	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/01/2009 - "Enclomiphene demonstrates promise in the management of secondary hypogonadism associated with obesity, metabolic syndrome and, possibly, infertility, and should undergo placebo-controlled, randomized clinical trials for these indications."
4.	Infertility (Sterility) 02/01/2009 - "Enclomiphene demonstrates promise in the management of secondary hypogonadism associated with obesity, metabolic syndrome and, possibly, infertility, and should undergo placebo-controlled, randomized clinical trials for these indications."
5.	Male Infertility (Male Sterility) 07/01/2023 - "Efficacy of Clomiphene Citrate Versus Enclomiphene Citrate for Male Infertility Treatment: A Retrospective Study." 07/01/2023 - "Since exogenous testosterone administration for hypogonadism management may disrupt the normal hormonal cascade necessary for spermatogenesis, clomiphene citrate (CC) and enclomiphene citrate (EC) are medications often used to manage hypogonadism and male infertility. "

Related Drugs and Biologics

1.	Clomiphene (Clomifene)
2.	Testosterone (Sustanon)
3.	Androgens
4.	Androgen Receptors (Androgen Receptor)
5.	Zuclomiphene (Zuclomifene)
6.	Tamoxifen
7.	Estrogen Receptors
8.	Nafoxidine
9.	Hormones (Hormone)
10.	Estrogens (Estrogen)

Related Therapies and Procedures

1.	Therapeutics
2.	Injections
3.	Duration of Therapy