An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
Also Known As:
Brugada ECG Pattern; Brugada Syndrome 1; Brugada Type ECG Pattern; Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome; Sudden Unexplained Death Syndrome; Sudden Unexplained Nocturnal Death Syndrome; Sudden Unexplained Nocturnal Death Syndrome (SUNDS); ECG Pattern, Brugada