Cannabinol

A physiologically inactive constituent of Cannabis sativa L.

Also Known As:

6H-Dibenzo(b,d)pyran-1-ol, 6,6,9-trimethyl-3-pentyl-

Networked: 55 relevant articles (4 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Cannabinoids: 5901
      - Cannabinol: 55
        9-(hydroxymethyl)-3-(1-adamantyl)hexahydrocannabinol: 3
        anabasum: 1
        cannabinolic acid: 1
        11-hydroxy-3-(1',1'-dimethylheptyl)hexahydrocannabinol
        11-hydroxycannabinol
        11-palmitoyloxy-delta(9)-tetrahydrocannabinol
        9-azacannabinol
        9-hydroxy-9-norhexahydrocannabinol
        9-hydroxyhexahydrocannabinol
        C1'-azacycloalkyl hexahydrocannabinol

Experts

1.	Chua, Raissa: 2 articles (11/2021 - 11/2021)
2.	Cruz Eng, Hillenn: 2 articles (11/2021 - 11/2021)
3.	Elvir-Lazo, Ofelia Loani: 2 articles (11/2021 - 11/2021)
4.	White, Paul F: 2 articles (11/2021 - 11/2021)
5.	Yumul, Firuz: 2 articles (11/2021 - 11/2021)
6.	Yumul, Roya: 2 articles (11/2021 - 11/2021)
7.	Esposito, G: 2 articles (10/2001 - 08/2001)
8.	Iuvone, T: 2 articles (10/2001 - 08/2001)
9.	Izzo, A A: 2 articles (10/2001 - 08/2001)
10.	Jordan, Erin: 1 article (11/2022)

Related Diseases

1.	Neuroblastoma 04/10/2022 - "Cannabinol Inhibits Cellular Proliferation, Invasion, and Angiogenesis of Neuroblastoma via Novel miR-34a/tRiMetF31/PFKFB3 Axis." 01/01/2023 - "In this study, we aimed to evaluate the potential protective effects of cannabinol (CBN) pre-treatment in an in vitro PD model, namely retinoic acid-differentiated SH-SY5Y neuroblastoma cells treated with 1-methyl-4-phenylpyridinium (MPP+). "
2.	Seizures (Absence Seizure) 01/01/2023 - "Using an optimized behavioral assay, we show that cannabidiol (CBD) and cannabichromene (CBC) and cannabinol (CBN) are effective at reducing seizures at low doses, with little evidence of sedation, and our novel HPLC assay indicates that CBC is effective with the lowest accumulation in larval tissues. " 09/10/2012 - "THC, cannabinol (CBN) and cannabidiol (CBD) in marijuana seizures exceeding 1g were quantified. " 01/01/2020 - "To investigate whether other cannabis-derived compounds could also reduce seizures, the antiepileptic effects of CBD, Δ9-tetrahydrocannabinol (THC), cannabidivarin (CBDV), cannabinol (CBN), and linalool (LN) were compared in both a chemically-induced (pentylenetetrazole, PTZ) and a DS (scn1Lab-/-) seizure models. "
3.	Catalepsy 08/01/1988 - "With the exception of cannabinol (CBN) and delta 1-tetrahydrocannabinol (delta 1-THC), the cannabinoids and olivetol (their biosynthetic precursor) demonstrated activity in the PBQ test exhibiting their maximal effect at doses of about 100 micrograms/kg. delta 1-THC only became maximally effective in doses of 10 mg/kg. This higher dose corresponded to that which induced catalepsy and is indicative of a central action. " 02/01/1995 - "Eight halogenated derivatives of cannabinol (CBN) substituted on the aromatic ring at the 2 and/or 4 position were synthesized and their pharmacological effects were evaluated by intracerebroventricular injection (50 micrograms/mouse) in mice, using hypothermia, pentobarbital-induced sleep prolongation, catalepsy and anticonvulsant effect as indices. " 02/01/1988 - "Cannabinol (CBN) and olivetol inhibited THC-induced catalepsy in the mornings and the evenings, but cannabidiol (CBD) exhibited this effect only in the evenings. "
4.	Osteosarcoma (Osteogenic Sarcoma) 08/01/2023 - "Cannabidiol is a non-psychoactive plant cannabinoid cannabinol (CBD) that has been shown to be effective against osteosarcoma; however, the molecular targets and mechanisms of CBD action in osteosarcoma remain unclear. "
5.	Psychotic Disorders (Schizoaffective Disorder) 10/20/1990 - "One hundred black men admitted to hospital with acute psychiatric symptoms were investigated for the presence of urinary cannabis metabolites in order to delineate the psychiatric role played by 'dagga', the potent South African cannabinol, in the study population and to determine the diagnostic value of the entity 'toxic psychosis (dagga)'. " 07/01/1998 - "Many older concerns about adverse effects on health (chromosomal damage, 'cannabinol psychosis', endocrine abnormalities, cardiac events, impaired immunity) no longer seem to elicit much interest. "

Related Drugs and Biologics

1.	Cannabinoids
2.	Cannabidiol
3.	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)
4.	Tretinoin (Retinoic Acid)
5.	cannabichromene
6.	olivetol
7.	Dronabinol (THC)
8.	cannabigerol
9.	Calcium Gluconate (CBG)
10.	Proteins (Proteins, Gene)

Related Therapies and Procedures

1.	Oral Administration
2.	Intravenous Administration
3.	Perioperative Period
4.	Ketogenic Diet
5.	Elective Surgical Procedures