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Calcium Gluconate (CBG)

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The calcium salt of gluconic acid. The compound has a variety of uses, including its use as a calcium replenisher in hypocalcemic states.

Also Known As:

CBG; Gluconate, Calcium; 3M Brand of Calcium Gluconate Monohydrate; Braun Brand of Calcium Gluconate; Calciofon; Calcipot; Calcium Braun; Calcivitol; Calglucon; Chaix et du Marais Brand of Calcium Gluconate; Coophavet Brand of Calcium Gluconate; Ebucin; Flopak Plain; Fresenius Kabi Brand of Calcium Gluconate; Glucal; Glucobiogen; Gluconate de Calcium Lavoisier; Gluconato Calc Fresenius; Merial Brand of Calcium Gluconate; Pharmtech Brand of Calcium Gluconate; D-Gluconic acid, calcium salt (2:1)

Networked: 573 relevant articles (36 outcomes, 52 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Lewis, J G: 9 articles (06/2015 - 07/2004)
2.	Torpy, D J: 8 articles (06/2015 - 05/2003)
3.	Lewis, John G: 7 articles (05/2015 - 11/2006)
4.	Ho, J T: 6 articles (01/2012 - 01/2006)
5.	Torpy, David J: 5 articles (05/2014 - 06/2007)
6.	Ho, Jui T: 4 articles (10/2011 - 06/2007)
7.	Shand, B I: 4 articles (04/2010 - 07/2004)
8.	Pugeat, Michel: 4 articles (06/2007 - 10/2002)
9.	Donihi, Amy C: 3 articles (11/2015 - 07/2009)
10.	Chapman, M J: 3 articles (06/2015 - 01/2006)

Related Diseases

1.	Burns 07/01/1993 - "20 patients with phosphor burn (TBSA 2%-75%) were cured by i.v. drop of calcium gluconate combined with other therapies including eschar conservation. " 01/01/2014 - "This study was designed to evaluate the efficiency and safety of arterial infusions of calcium gluconate to treat hydrofluoric (HF) acid burns of the distal human limbs. " 01/01/2014 - "Eligible patients with HF burn limbs, collected from January 2008 to October 2011, were given the arterial infusion of calcium gluconate into the injured limbs. " 11/01/2009 - "Intra-arterial calcium gluconate might be considered for finger burns caused by concentrated HF. " 01/01/2009 - "We conclude that intra-arterial calcium gluconate injection is a successful and well-tolerated therapy for HF burn associated with Raynaud's syndrome. "
2.	Hypocalcemia 11/01/2005 - "One to 2 g of IV calcium gluconate were effective for most patients with mild hypocalcemia; however, treatment of moderate to severe hypocalcemia with 2-4 g of IV calcium gluconate was often unsuccessful. " 11/01/2005 - "One to 2 g of IV calcium gluconate was effective in normalizing iCa for 23 out of 29 patients (79%) with mild hypocalcemia and 2-4 g was effective for 3 of 8 patients (38%) with moderate to severe hypocalcemia. " 07/01/2015 - "To avoid the risk of hypocalcemia, calcium gluconate was infused to the venous return line. " 11/01/2014 - "Amount of calcium gluconate intravenous used, hypocalcemia and duration of hospital stay did not show any significance." 11/01/2014 - "No significant difference was observed in amount of calcium gluconate intravenous use, hypocalcemia and hospital admission durations between titrated and loaded regimen groups, i.e., p = 0.160, 0.645 and 0.460, respectively. "
3.	Pain (Aches) 05/01/2014 - "Calcium gluconate soaks appear to be effective in reducing local pain and tissue damage. " 08/01/2013 - "Reviews on spinal disorders or pain syndromes were found in the Cochrane Back Group (CBG) and in the Pain, Palliative and Supportive Care Group (CPPSCG). " 01/01/2009 - "Pain and vasospasm were successfully treated by repeated intra-arterial calcium gluconate injection. " 07/01/2002 - "Locally inject with 10% calcium gluconate solution if the pain persists. " 11/01/1997 - "Intraarterial calcium gluconate perfusion was subsequently administered to the three patients with persistent subungual and pulp, or thenar pain. "
4.	Hyperkalemia 12/01/2012 - "Infusion of calcium gluconate may reduce early-onset hyperkalemia in a dose-dependent manner." 12/01/2012 - "The dosage of calcium gluconate during 24 h after birth was the only independent factor affecting early-onset hyperkalemia. " 01/01/2008 - "[Persistent severe hyperkalemia treated with a continous infusion of calcium gluconate]." 01/01/2006 - "The hyperkalemia was quickly normalized by medication with calcium gluconate and sodium bicarbonate. " 12/01/1985 - "If life threatening hyperkalemia develops during acute renal failure, 20 ml 10% calcium gluconate solution can be given intravenously in order to avoid ventricular fibrillation or cardiac arrest. "
5.	Neoplasms (Cancer) 06/01/2015 - "Although CBG is known to exhibit anti-cancer activities, very little is known about its potential mechanism(s) of action. " 07/01/2011 - "Analysis of the gene signal pathway further approved that smad2 gene had the relationships closely to other 16 cancer-related genes and could be used as a CBG to indicate the carcinogenic risks in YZR-SDW-NJ. " 05/01/2011 - "Taken together, these results indicated that CBG had potential immune system regulatory effects and suggested that this compound could be developed as a novel immunotherapeutic agent to treat immune-mediated diseases such as cancer." 01/01/2010 - "The complete extension of the tumor is much easier to detect with the cbg technique due to orientation of the anatomic landmarks. " 12/01/2008 - "The maximum of tumor infiltration length in CBG, MTG, ATG and STG were 11.68 mm, 13.08 mm, 8.64 mm and 9.98 mm respectively. "

Related Drugs and Biologics

1.	Hydrofluoric Acid (Hydrogen Fluoride)
2.	Calcium
3.	Magnesium Sulfate (Sulfate, Magnesium)
4.	Insulin (Novolin)
5.	Glucose (Dextrose)
6.	Calcium Chloride (Calcium Chloride, Anhydrous)
7.	cabergoline
8.	Potassium
9.	Interleukin-6 (Interleukin 6)
10.	Sodium Lactate

Related Therapies and Procedures

1.	Intravenous Infusions
2.	Subcutaneous Injections
3.	Aftercare (After-Treatment)
4.	Parathyroidectomy
5.	Injections