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Anticonvulsants (Antiepileptic Drugs)

Subscribe to New Research on Anticonvulsants

Drugs used to prevent SEIZURES or reduce their severity.

Also Known As:

Antiepileptic Drugs; Antiepileptics; Anticonvulsant Drugs; Anticonvulsive Agents; Anticonvulsive Drugs; Agents, Anticonvulsive; Agents, Antiepileptic; Drugs, Anticonvulsant; Drugs, Anticonvulsive; Drugs, Antiepileptic; Antiepileptic Agents

Networked: 8394 relevant articles (701 outcomes, 990 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 56
  - Therapeutic Uses: 297
    - Central Nervous System Agents: 29
      - Anticonvulsants: 8394

Experts

1.	Luszczki, Jarogniew J: 60 articles (02/2016 - 04/2003)
2.	Czuczwar, Stanisław J: 56 articles (07/2015 - 01/2002)
3.	Löscher, Wolfgang: 50 articles (08/2015 - 01/2002)
4.	Perucca, Emilio: 49 articles (08/2015 - 01/2002)
5.	Czuczwar, Stanislaw J: 38 articles (01/2015 - 04/2003)
6.	Verrotti, Alberto: 28 articles (11/2015 - 01/2002)
7.	Tomson, Torbjörn: 27 articles (09/2015 - 06/2002)
8.	Brodie, Martin J: 26 articles (11/2015 - 04/2002)
9.	Sander, Josemir W: 26 articles (05/2015 - 01/2005)
10.	French, Jacqueline A: 24 articles (05/2015 - 04/2002)

Related Diseases

1.	Seizures (Seizure) 10/01/2011 - "Although surgical resection of the hippocampus bestows improved seizure regulation in most cases of intractable TLE, this choice can cause lasting cognitive deficiency and reliance on antiepileptic drugs. " 11/01/2010 - "Improved understanding of the mechanisms of action of antiepileptic drugs (AEDs) may help the clinician to make a rational choice of the AED based on the knowledge of which drug is most effective against each type of seizure. " 12/01/2006 - "Antiepileptic drugs (AEDs) suppress seizures but appear to have little effect on long-term remission, and the choice of AED is for the most part arbitrary with most AEDs having a similar success rate when used as the first drug. " 09/01/1999 - "With antiepileptic drugs, almost all had control of clinical seizures, and most improved in mental status. " 09/01/1998 - "The treatment, consisting of 43 SCP training sessions and 22 behavioral control sessions, yielded a highly significant reduction of seizure frequency to about 7.5/week; such a decrease had never been observed after administration of new anticonvulsant drugs, nor after the callosotomy. "
2.	Epilepsy (Aura) 01/01/2013 - "Despite the frequent use of anticonvulsant drugs, remarkably little is known about the safety and efficacy of most of these medications in the pediatric epilepsy population. " 01/03/2012 - "We retrospectively examined treatment records of developmentally disabled adults with highly refractory epilepsy to determine whether any combinations of 8 of the most commonly used antiepileptic drugs (AEDs) possessed superior efficacy. " 03/01/2006 - "The availability of ten new antiepileptic drugs since the late 1980s has not dramatically improved the outcome of refractory epilepsy. " 01/19/1998 - "In spite of some 30 years of 'modern' neuroscientific epilepsy research, most novel, clinically effective second generation anticonvulsants have been found by screening (i.e. " 12/01/1993 - "The increasing availability of new antiepileptic drugs coupled with the increasing success of epilepsy surgery has dramatically improved the life of many children with epilepsy."
3.	Pain (Aches) 01/01/2010 - "There is no evidence that anticonvulsants are effective for acute pain. " 01/01/2005 - "There is no evidence that anticonvulsants are effective for acute pain. " 01/01/2000 - "There is no evidence that anticonvulsants are effective for acute pain. " 01/01/2000 - "There is no evidence that anticonvulsants are effective for acute pain. " 10/01/2009 - "Based on several studies as STEP, Spanish Pain Society recommendations included antidepressant and anticonvulsant drugs as the first line treatment. "
4.	Neuralgia (Stump Neuralgia) 08/01/2008 - "Despite important advances in available knowledge, management of neuropathic pain remains incomplete, and results from experimental and clinical studies indicate that some anticonvulsants show promise for treating neuropathic pain. " 04/01/2009 - "Unfortunately, even when effective in other types of neuropathic pain, anti-depressants and anticonvulsants have not yet proven effective for treating the symptoms of CIPN." 01/01/2009 - "Antiepileptic drugs (AED) have proved effective in relieving neuropathic pain. " 06/01/2006 - "Both basic and clinical research has demonstrated that antiepileptic drugs can be effective in alleviating neuropathic pain. " 08/01/2005 - "First-generation antiepileptic drugs have been shown to be effective in neuropathic pain. "
5.	Bipolar Disorder (Mania) 01/01/2003 - "However, the efficacy of antiepileptic drugs investigated in the treatment of bipolar disorder differs and most promising effects are seen in combination therapy with mood stabilizers. " 01/01/2005 - "Anticonvulsants and other mood stabilizers may be especially helpful in treating bipolar disorder with significant comorbidity." 01/01/2006 - "Other new antiepileptic drugs may also be effective in bipolar disorder but more solid evidence of their efficacy is needed." 04/01/2010 - "Understanding the mechanisms of action and identifying similarities between anticonvulsants effective in bipolar disorder may also enhance our understanding of the underlying pathophysiology of the disorder." 01/01/2004 - "Newer anticonvulsants have diverse psychotropic profiles, and although not generally effective for acute mania, may have utility for other aspects of bipolar disorders (e.g. "

Related Drugs and Biologics

1.	Valproic Acid (Valproate, Semisodium)
2.	Carbamazepine (Tegretol)
3.	Antidepressive Agents (Antidepressants)
4.	lamotrigine (Lamictal)
5.	Phenobarbital (Luminal)
6.	Opioid Analgesics (Opioids)
7.	Phenytoin (Dilantin)
8.	gabapentin (Neurontin)
9.	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
10.	topiramate (Topamax)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Ketogenic Diet
3.	Aftercare (After-Treatment)
4.	Vagus Nerve Stimulation
5.	Massage (Reflexology)