Central Nervous System Agents

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)

Also Known As:

Networked: 51 relevant articles (3 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Preskorn, Sheldon H: 2 articles (01/2022 - 01/2017)
2.	Chien, Edward K: 1 article (12/2022)
3.	Gerlanc, Nicole: 1 article (12/2022)
4.	Grantz, Katherine L: 1 article (12/2022)
5.	Grewal, Jagteshwar: 1 article (12/2022)
6.	Grobman, William A: 1 article (12/2022)
7.	Hinkle, Stefanie N: 1 article (12/2022)
8.	Newman, Roger B: 1 article (12/2022)
9.	Ranzini, Angela C: 1 article (12/2022)
10.	Sciscione, Anthony: 1 article (12/2022)

Related Diseases

1.	Mental Disorders (Mental Disorder) 03/01/2017 - "PCPs, who treat the majority of patients with mental illness, reported a significant reduction in medication costs for both central nervous system and non-central nervous system drugs." 01/01/2019 - "Moreover, 20.1% of SCA s were diagnosed with psychiatric disease and 30% had central nervous system drugs prescribed. " 01/01/2017 - "The column discusses the reasons behind these different rates of development of psychiatric and/or central nervous system drugs compared with drugs in the areas of infectious disease, oncology, and immunology, and it predicts that this situation will change over the next century as we develop an improved understanding of the neurobiology underlying specific psychiatric illnesses."
2.	Neurodegenerative Diseases (Neurodegenerative Disease) 06/01/2010 - "Moreover, in order for drugs to be effective in the treatment of neurodegenerative diseases, they must be capable of penetrating the blood-brain barrier, whereas more than 98% of all potential central nervous system drugs don't cross. " 01/01/2021 - "This study reported for the first time that Centella asiatica compounds demonstrated high capability to cross the BBB, comparable to central nervous system drugs, and therefore warrant further development as therapeutics for the treatment of neurodegenerative diseases."
3.	Communicable Diseases (Infectious Diseases) 01/01/2017 - "The column discusses the reasons behind these different rates of development of psychiatric and/or central nervous system drugs compared with drugs in the areas of infectious disease, oncology, and immunology, and it predicts that this situation will change over the next century as we develop an improved understanding of the neurobiology underlying specific psychiatric illnesses."
4.	Neoplasms (Cancer) 01/14/2019 - "We concluded that Some Central Nervous system drugs show a great potential as anti-cancer in vitro, in vivo and clinical trials through different mechanisms and pathways in different types of cancer that reveal a promising evidence for the repurposing of CNS drugs for new indications." 01/14/2019 - "In our review, we will review the anti-cancer effect of some CNS drugs, including both therapeutic and preventive, by searching the literature for preclinical or clinical evidence for anticancer potential of central nervous system drugs over the last 8 years period (2010-2018) and including only evidence from Q1 journals as indicated by Scimago website (www.scimagojr.com). " 04/01/2014 - "Furthermore, while anti-cancer drugs altered [methyl-(3)H]choline uptake, central nervous system drugs did not affect [methyl-(3)H]choline uptake." 04/01/2014 - "In addition, we examined the influence of anti-cancer drugs and central nervous system drugs on the transport of [methyl-(3)H]choline. " 01/01/2022 - "In these articles, we have shown that case reports often involved long-term or semi-long-term treatments such as cancer or human immunodeficiency virus therapies, antiepileptic drugs, or central nervous system drugs. "
5.	Dementia (Dementias) 01/01/2013 - "In this paper some neurophysiological cutting-edge techniques will be presented that provide innovative information and deal with the broad issue of the role of neurophysiology for the assessment of patho-physiological aging and dementia also providing new insight to the actions of central nervous system drugs at the cortical level. " 04/01/1993 - "The lower the mini-mental status score in patients with any dementia, the greater the mean number of central nervous system agents used. " 09/01/2008 - "The aim of the present study was to compare the use of central nervous system drugs and analgesics among people aged 85 years or older, with and without dementia. " 09/01/2008 - "The use of central nervous system drugs and analgesics among very old people with and without dementia." 09/01/2021 - "Differences were seen in the provision of cholinesterase inhibitors, antipsychotics, and central nervous system agents at visits for patients with dementia (p = 0.0011, <0.0001, and 0.0011 respectively). "

Related Drugs and Biologics

1.	Antipsychotic Agents (Antipsychotics)
2.	Analgesics (Analgesic Drugs)
3.	Dexmedetomidine
4.	Alkaloids
5.	Cardiovascular Agents
6.	Histamine Antagonists (Antihistamines)
7.	Anticonvulsants (Antiepileptic Drugs)
8.	Gastrointestinal Agents
9.	Cholinesterase Inhibitors (Anticholinesterases)
10.	Barbiturates

Related Therapies and Procedures

1.	Therapeutics
2.	Home Nursing (Nursing, Home)
3.	Enteral Nutrition (Feeding, Tube)