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plasmodione

structure in first source

Also Known As:

3-(4-(trifluoromethyl)benzyl)menadione

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Davioud-Charvet, Elisabeth: 3 articles (05/2021 - 01/2016)
2.	Blandin, Stephanie: 2 articles (05/2021 - 01/2016)
3.	Cichocki, Bogdan Adam: 2 articles (05/2021 - 01/2021)
4.	Donzel, Maxime: 2 articles (05/2021 - 01/2021)
5.	Elhabiri, Mourad: 2 articles (05/2021 - 01/2021)
6.	Cianférani, Sarah: 1 article (05/2021)
7.	Cotos, Leandro: 1 article (05/2021)
8.	Khobragade, Vrushali: 1 article (05/2021)
9.	Schaeffer-Reiss, Christine: 1 article (05/2021)
10.	Strub, Jean-Marc: 1 article (05/2021)

Related Diseases

1.	Malaria 05/24/2021 - "Plasmodione (PD) is a potent antimalarial redox-active drug acting at low nM range concentrations on different malaria parasite stages. " 01/01/2021 - "Plasmodione (PD) is a potent antimalarial redox-active 3-benzyl-menadione acting at low nanomolar range concentrations on different malaria parasite stages. " 01/01/2016 - "Here we report a detailed parasitological characterization of the in vitro activity profile of the lead compound 3-[4-(trifluoromethyl)benzyl]-menadione 1c (henceforth called plasmodione) against intraerythrocytic stages of the human malaria parasite Plasmodium falciparum We show that plasmodione acts rapidly against asexual blood stages, thereby disrupting the clinically relevant intraerythrocytic life cycle of the parasite, and furthermore has potent activity against early gametocytes. "
2.	Parasitemia 01/01/2017 - "Our results demonstrate that plasmodione did not reduce the level of parasitemia in B. "

Related Drugs and Biologics

1.	Antimalarials (Antimalarial Agents)
2.	Vitamin K 3 (Menadione)