Naphthalenes

Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.

Networked: 9 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Liu, Guorui: 1 article (09/2012)
2.	Hu, Jicheng: 1 article (09/2012)
3.	Zheng, Minghui: 1 article (09/2012)
4.	Xiao, Ke: 1 article (09/2012)
5.	Du, Bing: 1 article (09/2012)
6.	Nie, Zhiqiang: 1 article (09/2012)
7.	Zhang, Bing: 1 article (09/2012)
8.	Evans, Ian D: 1 article (12/2006)
9.	McCluskey, Adam: 1 article (12/2006)
10.	Qi, Ying: 1 article (12/2006)

Related Diseases

1.	Neoplasms (Cancer) 08/01/1994 - "A cohort mortality study was conducted among 9028 (3042 women, 5986 men) workers potentially exposed to chlorinated naphthalenes (chloracnegens structurally similar to dioxins) and asbestos in the manufacture of Navy cable during World War II. Based on mortality through December 31, 1985, standardized mortality ratios (SMRs) for all cancers was 1.03 in women (95% confidence interval [CI] = 0.9 to 1.17) and 1.18 in men (95% CI = 1.10 to 1.26). "
2.	Hepatocellular Carcinoma (Hepatoma) 09/01/2001 - "In this study, the relative potencies (REPs) of mixtures of polychlorinated naphthalenes (PCNs), polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs), to induce in vitro ethoxyresorufin-O-deethylase (EROD) in PLHC-1 fish hepatoma cells, H4IIE wild type (H4IIE-wt) rat hepatoma cells, and recombinant H4IIE cells (H4IIE-EROD) were determined. "
3.	Stupor 03/01/2004 - "Narcosis appeared to primarily contribute to embryo mortality and to be predominantly controlled by the concentration of naphthalenes. "
4.	Seizures (Seizure) 12/20/2006 - "Additionally the two naphthalenes 32 and 33 further identified that 15 items in 9 seizures were produced via the more specific ephedrine/hydriodic acid/red phosphorus method. "
5.	Heart Failure 10/20/2005 - "Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis."

Related Drugs and Biologics

1.	Cytochrome P-450 CYP1A1 (CYP1A1)
2.	Aromatic Polycyclic Hydrocarbons (Polycyclic Aromatic Hydrocarbons)
3.	Polychlorinated Biphenyls (PCBs)
4.	Dioxins
5.	Asbestos
6.	Aldosterone Synthase (CYP11B2)
7.	Lipoxygenase Inhibitors
8.	Arachidonic Acid (Vitamin F)
9.	Phosphorus
10.	Ethyl Ether (Ether)