Paragangliomas 3

mutation in SDHC

Also Known As:

Carotid Body Tumors and Multiple Extraadrenal Pheochromocytomas; Glomus Tumors, Familial, 3; Paraganglioma, Familial Malignant; Paragangliomas 4; Paragangliomas, Hereditary Extraadrenal; Pheochromocytoma, Extraadrenal, and Cervical Paraganglioma; Pheochromocytoma, Familial Extraadrenal

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Alveolar Soft Part Sarcoma
2.	Clear Cell Sarcoma
3.	Granular Cell Tumor
4.	Sarcoma (Soft Tissue Sarcoma)
5.	Pheochromocytoma

Experts

1.	Imamura, Tetsuo: 1 article (03/2012)
2.	Ishikawa, Yuichi: 1 article (03/2012)
3.	Tsuji, Kaori: 1 article (03/2012)
4.	Bäckdahl, Martin: 1 article (05/2005)
5.	Carling, Tobias: 1 article (05/2005)
6.	Edström Elder, Elisabeth: 1 article (05/2005)
7.	Ekström, Tomas J: 1 article (05/2005)
8.	Frisk, Tony: 1 article (05/2005)
9.	Geli, Janos: 1 article (05/2005)
10.	Larsson, Catharina: 1 article (05/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Paragangliomas 3:

1.	Messenger RNA (mRNA)IBA 05/01/2005 - "A panel of 18 pheochromocytomas (14 benign, and 4 malignant) and 11 abdominal paragangliomas (4 benign, and 7 malignant) were characterised for somatic deletions and mRNA expression status of RIZ1 using loss of heterozygosity (LOH) analysis and real-time quantitative PCR, respectively. "
2.	Proteins (Proteins, Gene)FDA Link 11/01/1994 - "Abnormal expression of p53 protein was absent from 15 morphologically typical adrenal (2) and extra-adrenal(13) paragangliomas, 3 were overtly malignant, when sought for using the DO-7 antibody (Dako), whilst colon adenocarcinomas known to abnormally express the protein and used as controls were consistently positive. "
3.	ParaffinIBA 03/01/2012 - "To identify the best marker for alveolar soft part sarcoma in formalin-fixed, paraffin-embedded tissues, we evaluated the sensitivity and specificity of the detection of the ASPSCR1-TFE3 fusion transcript along with the immunoreactivity for TFE3 and CD147 in 24 alveolar soft part sarcomas and 23 non-alveolar soft part sarcoma tumors, including 5 granular cell tumors, 5 paragangliomas, 3 clear cell sarcomas, and 10 clear cell renal cell carcinomas. "
4.	Formaldehyde (Formol)FDA Link 03/01/2012 - "To identify the best marker for alveolar soft part sarcoma in formalin-fixed, paraffin-embedded tissues, we evaluated the sensitivity and specificity of the detection of the ASPSCR1-TFE3 fusion transcript along with the immunoreactivity for TFE3 and CD147 in 24 alveolar soft part sarcomas and 23 non-alveolar soft part sarcoma tumors, including 5 granular cell tumors, 5 paragangliomas, 3 clear cell sarcomas, and 10 clear cell renal cell carcinomas. "