fukinolic acid

also a carboxypeptidase A inhibitor; RN given for (S-(R*,S*))-isomer; structure in first source

Also Known As:

(2R,3S)-2-(3,4-Dihydroxybenzyl)-3-(((2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl)oxy)-2-hydroxysuccinic acid

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Inflammation (Inflammations) 10/01/2001 - "The present studies suggest the potential effect of fukinolic acid and cimicifugic acids of Cimicifuga rhizomes in preventing collagen degradation by collagenases or collagenolytic enzymes under pathological conditions, wound healing, or inflammation."
2.	Infections 02/01/2019 - "Identification of fukinolic acid from Cimicifuga heracleifolia and its derivatives as novel antiviral compounds against enterovirus A71 infection."
3.	Contracture 11/01/1998 - "Concentration response curves for the Ca2+-induced contracture of depolarized aortic strips with isotonic high K+ were not affected by cimicifugic acid D or fukinolic acid. "
4.	Breast Neoplasms (Breast Cancer) 11/20/2002 - "Six of these antioxidants were found to reduce menadione-induced DNA damage in cultured S30 breast cancer cells with the following order of potency: methyl caffeate (2) > caffeic acid (1) > ferulic acid (3) > cimiracemate A (9) > cimiracemate B (10) > fukinolic acid (5). "

1.	Collagenases (Collagenase)
2.	Enzymes
3.	Collagen
4.	Acids
5.	Vitamin K 3 (Menadione)
6.	Antiviral Agents (Antivirals)
7.	Antioxidants
8.	cimiracemate A
9.	cimiracemate B
10.	cimicifugic acid