Contracture

02/01/1999 - "Run training significantly reduced the rate of Na+-dependent clearance of [Ca2+]c during the caffeine-induced contractures. "
08/01/1993 - "After Ca2+ loading (120 s), the minimal caffeine concentration required to evoke a contracture in fatigued fibers (5.7 +/- 0.3 mM) was significantly greater than that of control fibers (3.1 +/- 0.4 mM), an effect that persisted with prolonged incubation of the skinned fibers. "
06/01/1992 - "In all cases, CICR evoked at pH 6.5 resulted in larger caffeine contractures than that evoked at 7.0, suggesting that more Ca2+ was released during CICR at the higher pH. Accordingly, rate constants for CICR were significantly greater at pH 7.0 than at pH 6.5. "
10/01/1989 - "The concentration of caffeine alone that increased the contracture tension by 7% averaged 6.7 +/- 0.3 mM for vastus, significantly greater than 4.1 +/- 0.2 mM for the rectus muscle biopsies. "
01/01/1990 - "The findings that human type I muscle fibers have higher caffeine sensitivity than type II muscle fibers should be helpful for the interpretation of the in vitro contracture test done in muscle strips containing type I and type II fibers in varying proportions."

09/01/1990 - "The effect of varying temperatures on biopsies of skeletal muscle from these animals showed a marked decrease in contracture response to halothane when the muscle was cooled to 25 degrees C. "
09/01/1990 - "The rate of tension development of cooling-induced contractures in the absence or presence of halothane was significantly greater in denervated (2-90 days) than in innervated muscles. "
07/01/1987 - "The magnitude of contractures was, however, significantly greater in the dynamic than in the static halothane test for halothane concentrations less than 3%, but this did not influence diagnosis. "
04/01/2011 - "The aim of this study was to investigate whether these agents can be considered possible substitutes for halothane in a modified in-vitro contracture test. "
04/01/1987 - "Studies of the halothane-cooling contractures of skeletal muscle."

01/01/2021 - "The technique of fusiform capsulectomy of posterior capsule to correct the severe flexion contracture during primary TKA is safe and effective and could provide good short-term results."
09/15/2006 - "Capsular contracture in smooth implants showed significantly greater pressure values of tonometry, and the smooth implant capsule was significantly thicker than the textured implant capsule. "
01/01/1989 - "When the electrical current was applied in a transverse manner, there was a statistically significant reduction in the amount of posterior capsule (p less than 0.005) and anterior cruciate ligament (ACL) (p less than 0.05) contracture. "
10/01/2019 - "The IMR model was associated with reduced incidence of fibrous capsule contracture compared with IR (0% vs 18.75%, P = 0.0267). "
04/01/2011 - "It appears that particularly posttraumatic elbow stiffness with contracture of the capsule and minor alterations of the joint surface can achieve improvement in mobility and patient satisfaction. "

04/01/2019 - "Clinicians can expect better outcome after collagenase infiltration in patients with less flexion contracture and in patients showing good initial self-reported hand function."
10/01/2015 - "Collagenase-treated participants experienced significant reduction in contracture and an increased range of motion compared with placebo-treated participants. "
04/01/2019 - "Collagenase treatment resulted in considerable improvement in flexion contracture as well as patient-reported hand function at the 1-year follow-up. "
02/01/2016 - "However, the late results and recurrence rates of capsular contracture were not included in this study; collagenase seemed effective for the reduction of capsular tissue around the implants. "
02/01/2019 - "Collagenase is a viable first-line treatment for MCP joint contractures. "

05/01/1989 - "1. The protective effects of some calcium antagonists against different forms of calcium overload contracture were investigated in embryonic chick cardiac myocytes. "
09/01/1983 - "Our results suggest that contracture can be reversed and that functional recovery can be improved in spite of increased tissue calcium."
12/01/1991 - "The results reported in the present study may be related to the impaired relaxation and contracture described in vivo within the first minutes of a postischemic reperfusion and before any change in calcium homeostasis."
02/01/1979 - "The study does not discriminate between rigor and rised cytosolic calcium as mechanisms causing hypoxic contracture, but demonstrates that hypoxic contracture is not directly dependent on the availability of intracellular calcium."
06/01/1972 - "However, the fact that contractures are prolonged in the cold, and the finding that repriming is delayed, can be utilized in further studies to clarify the mechanism that controls the release of calcium."

05/01/1993 - "The purpose of this study was to assess the efficacy of textured silicone implants in reducing the incidence of capsular contracture. "
12/01/2023 - "Discussion: Baker Grade IV Capsular Contracture Is Correlated with an Increased Amount of Silicone Material: An Intrapatient Study."
12/01/2023 - "Baker Grade IV Capsular Contracture Is Correlated with an Increased Amount of Silicone Material: An Intrapatient Study."
11/01/2022 - "The purpose of this study was to investigate in a single-surgeon series the incidence of capsular contracture associated with access incision locations in silicone vertical augmentation mastopexy. "
09/01/2021 - "The goal of the present study was to evaluate the correlation between capsular contracture and 3D images of the silicone implants by using magnetic resonance imaging (MRI) with sampling perfection with application optimized contrast using different flip angle evolutions (SPACE) sequence. "

05/10/1988 - "All three compounds exerted a significant anti-ischaemic effect, as indicated by an improved recovery of functional parameters (left ventricular pressure and coronary perfusion), a delayed onset of the ischaemic contracture, and an enhanced recovery of biochemical (CrP, ATP and adenylate energy charge) parameters. "
01/01/2007 - "Adenosinergic contracture inhibition was eliminated by A(1)AR gene knockout (KO), mimicked by A(1)AR overexpression, and was associated with preservation of myocardial [ATP]. "
05/01/2015 - "In the present study, we have investigated the involvement of the Ca(2+)/ATP-activated K(+) channels in the regulation of both acute A1-withdrawal and CCk-8-induced contractures in the GPI preparation. "
09/01/1989 - "These studies lead us to conclude that the relatively poor recovery of contractile response of human atrial trabeculae, together with contracture reported previously at lower temperatures (1 degree and 4 degrees C), is not due to a failure to maintain adenosine triphosphate levels."
07/30/2020 - "Mel can alleviate myocardial IR injury in isolated rat hearts by inhibiting cardiac contracture, the mechanism of which may involve the upregulation of ATP in the cardiac myocytes to lessen the tear of membrane and reduce cell content leakage."

02/01/2016 - "In conclusion, botulinum toxin injection in subacute patients was more helpful for spasticity, contracture, and function than in chronic patients. "
10/01/2019 - "Botulinum toxin is effective for the treatment of spasticity and is widely used in patients who have joints with contractures. "
11/01/2018 - "Botulinum toxin can be helpful, as a therapeutic treatment in relieving spasticity and as a diagnostic tool in determining the underlying cause of the contracture. "
09/30/2022 - "Botulinum toxins when paired with physical exercises to treat hypertonia, a condition in which a little change in tone can affect a child's balance, strength and motor function, as well as secondary concerns such as malalignment and repair contractures. "
06/01/2019 - "A programme for contracture management comprising serial casting, botulinum toxin, motor training and splinting can be useful in improving joint range."

07/01/2020 - "We hypothesized that contracture release combined with Botox injection would lead to improved functional outcome scores when compared with current treatment methods. "
10/01/2016 - "The purpose of this study was to evaluate whether Botulinum toxin A improves knee extension for any patient with flexion contractures following TKA. "
01/01/2021 - "Botulinum Toxin Type A as a Tool for Correcting Capsular Contracture after Reconstructive Breast Surgery."
08/01/2019 - "Botulinum toxin type A injection increases ROM in hip, knee and ankle joint contractures in CP. "
10/01/2016 - "The initial post-operative flexion contracture averaged 19° ± 6° in the Botulinum toxin A group and 13° ± 3° in the saline group. "

07/01/2004 - "If collagen synthesis could be altered to minimize the contracture, then the outcome could be improved. "
08/08/2023 - "This study explores the essential role collagen fibers may play in muscle contracture in GMC. "
01/01/2022 - "The purpose of this study was to investigate the effects of different durations of static progressive stretching (SPS) on posttraumatic knee contracture in rats, including range of motion (ROM), gait analysis, myofibroblast proliferation, and collagen regulation. "
01/01/2020 - "In this study, the effect of compressive forces on the meniscus will be evaluated in a litter of 12 Dobermann Pinschers, of approximately 2 months of age, euthanized as affected by the quadriceps contracture muscle syndrome of a single limb focusing on extracellular matrix remodeling and cell-extracellular matrix interaction (i.e., meniscal cells maturation, collagen fibers typology and arrangement). "
07/01/2017 - "[Purpose] The purpose of this study was to determine whether collagen fibers cause a difference in a contracture resulting from a combination of joint fixation and hindlimb unloading as compared to joint fixation only. "

01/01/2014 - "In this study we report our experience on surgical treatment of adult hip flexion contracture due to neurological diseases; we have tried to outline an algorithm to choose the best treatment avoiding useless or too aggressive therapies. "
03/01/2016 - "Within 2 months of therapy, fibrotic areas softened, his contracture nearly resolved, and there was marked improvement in his mobility. "
04/01/2015 - "By employing a detailed clinical assessment to guide surgical treatment followed by focused therapy, we have markedly improved flexion contractures in digits with moderate to severe camptodactyly. "
09/15/2016 - "The therapy applied had no significant changes in the clinical neurological status of the patients, but yet it provided some improvement in ankle contractures, better mobility, and a more stable gait. "
04/01/2016 - "The mean flexion contracture improved significantly in (p = 0.001) in 91% of patients after Astym therapy. "

10/01/1988 - "Although the weight of evidence generally indicates that improved contracture rates with retropectoral placement of the prosthesis and excellent aesthetic results can be obtained with this approach, there remains a significant cadre of surgeons who believe their own retromammary results are equal to or better than the alternative. "
11/01/2018 - "All patients underwent a significant improvement of socket contracture enabling retention of the prosthesis and were satisfied with the outcomes. "
05/01/2012 - "All 3 patients who had surgery experienced significant improvement of socket contracture that enabled patients to wear a prosthesis again. "
01/01/2005 - "Although surgical techniques and the quality of mammary prostheses have been improved significantly in recent years, capsular contracture attendant on prosthetic mammary reconstruction remains a major flaw. "
11/01/2012 - "Its putative advantages include improved positioning of the prosthesis, better definition of the inframammary fold, amelioration of potential contracture, and overall enhancement of cosmesis. "

11/01/2009 - "This type of breast contracture can be successfully eliminated with the author-suggested, improved free-skin grafting technique. "
01/01/2007 - "Skin grafting is widely used for the treatment of postburn contractures. "
04/01/2019 - "To use both acellular human dermis and skin grafting simultaneously for improved skin grafting without contracture. "
03/01/2011 - "As a result of the counter flaps transposition, the contracture is eliminated; the web space's shape and depth are restored by the use of flaps alone or in combination with skin grafting. "
11/01/2023 - "Combined cervicothoracic skin grafting is an independent risk factor for neck contracture. "

01/01/2023 - "At one-year follow-up of the randomized group, both dynamic splinting (median -8.5°, interquartile range [IQR] -13.5, -5) and serial casting (median -11.0°, IQR -16, -5) resulted in significant reduction of contracture (P < 0.001). "
03/01/2021 - "Splints that allowed extension and improved finger muscle tone and contracture were made for the patient. "
05/01/2019 - "For the five fingers severely contracted and treated with Capener splint intervention, the mean passive PIP joint contracture was 62.0° at baseline, 21.0° immediately, further improved to 6.0° by 4 weeks, and maintained 8.0° by 12 weeks after the last manipulation. "
08/01/2013 - "The purpose of this systematic review was to evaluate the safety and efficacy of dynamic splinting as it is used to treat joint contracture in lower extremities, and to determine if duration on total hours of stretching had an effect on outcomes. "
09/01/2009 - "Flexion contractures were rare and responded well to dynamic splinting."

12/01/2015 - "This study shows the importance of physical therapy and splinting, achieving good results in preventing contracture, improving range of motion, muscle force and good cosmetic results."
02/01/2007 - "Significant improvement of the range of the motion in the elbow joint in the children with post-traumatic elbow contracture is attained by physical therapy."
10/01/2020 - "Inclusion criteria were patients undergoing PMGR due to forefoot and/or hindfoot injury with medial gastrocnemius contracture that has not improved with physical therapy. "
01/01/2019 - "Physical therapy and bracing proved helpful for the contractures to try to stop progression. "
04/01/1996 - "At a mean follow-up of 22 months following arthrolysis and physical therapy, mean flexion contracture improved to 2 degrees, total range of motion improved to 125 degrees, and mean Lysholm score improved to 94."