lanatoside C

RN given refers to (3beta,5beta,12beta)-isomer

Also Known As:

Allocor; Cedilanid; Ceglunat; Celanide; Lanocide; isolanid; lanatigen C; 3-((O beta-D-glucopyranosyl-(1-4)-O-3 beta-O-acetyl- 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6- dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6- dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12 beta,14-dihydroxy-5 beta-card-20(22)-enolide

Networked: 77 relevant articles (3 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Badr, Christian E: 3 articles (04/2016 - 11/2011)
2.	Tannous, Bakhos A: 3 articles (04/2016 - 11/2011)
3.	Zhang, Dan: 2 articles (01/2019 - 01/2018)
4.	Niers, Johanna M: 2 articles (04/2016 - 11/2011)
5.	Xiao, Rong: 2 articles (09/2011 - 12/2008)
6.	Shao, Yan: 1 article (01/2022)
7.	Wang, Jie: 1 article (01/2022)
8.	Wang, Qiang: 1 article (01/2022)
9.	Yang, Zhirong: 1 article (01/2022)
10.	Yin, Lu: 1 article (01/2022)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2021 - "Combination of 131I-trastuzumab and lanatoside C enhanced therapeutic efficacy in HER2 positive tumor model." 01/01/2021 - "Biodistribution studies using 131I-trastuzumab or combination of 131I-trastuzumab and lanatoside C showed tumor uptake in BALB/c nude mice bearing HER2 positive NCI-N87 tumor xenograft model. " 11/27/2019 - "Our studies provide a novel molecular insight of anti-cancer activities of Lanatoside C in human cancer cells." 11/27/2019 - "In this current study, we explored the underlying mechanism responsible for the anti-cancer activity of Lanatoside C against breast (MCF-7), lung (A549), and liver (HepG2) cancer cell lines. " 01/01/2021 - "In addition, mice received lanatoside C alone (p = 0.085) or 131I-trastuzumab alone (p = 0.160) did not significantly inhibit tumor progression compared with control. "
2.	Cardiac Arrhythmias (Arrythmia) 04/01/1993 - "Hemodynamic studies before and after the use of cedilanid, simple QRS scoring, changes on the score of AMI and cardiac arrhythmia were analysed on 24 cases of AMI. " 01/01/2010 - "To report a case of cardiac arrhythmia related to a low dose of endovenous lanatoside C. " 07/01/1948 - "Treatment of complete arrhythmia with lanatoside C." 01/01/1984 - "When given after lanatoside C, nifedipine was unable to suppress cardiac arrhythmias but improved the survival rate (8 out of 19). " 01/01/1984 - "Group II (N = 19): cats intoxicated with lanatoside C were treated with nifedipine in the same doses and conditions described for Group I. The calcium antagonist was administered as soon as cardiac arrhythmias appeared. "
3.	Heart Failure 01/01/1946 - "The use of lanatoside C in the treatment of congestive heart failure." 01/01/1945 - "The intravenous administration of lanatoside C to patients taking maintenance doses of folia digitalis up to the date of hospitalization with recurrent congestive heart failure." 10/01/2021 - "In the present study, lanatoside C, an FDA-approved cardiac glycoside used for the treatment of heart failure, was demonstrated to have anti-proliferative and cytotoxic effects on cervical cancer cells, with abrogation of cell migration in a dose-dependent manner. " 01/01/1958 - "The influence of cedilanid and glutamic acid on electrolyte metabolism in cardiac failure." 09/01/1988 - "Comparative effects of captopril, nitroprusside, dopamine and lanatoside C on a new model of rabbit congestive heart failure."
4.	Heart Diseases (Heart Disease) 07/01/1959 - "Effects of lanatoside C on cardiovascular hemodynamics; acute digitalizing doses in subjects with normal hearts and with heart disease without failure." 01/01/1949 - "Studies on the circulation in man; the effect of cedilanid (lanatoside C) on cardiac output and blood pressure in the pulmonary circulation in patients with compensated and decompensated heart disease." 10/15/1959 - "[The effect of simultaneous administration of cedilanid with glutamic acid and ATP on electrolyte metabolism in decompensated heart diseases. " 01/01/1959 - "[Pharmacological and clinical considerations on the association ATP-cardiac glycosides (lanatoside C, strophanthin) in the treatment of arteriosclerotic heart disease]."
5.	Myocardial Infarction 04/01/1993 - "[A study on the hemodynamic effect of cedilanid in the treatment of acute myocardial infarction]." 08/01/1952 - "The usefulness of intravenous lanatoside C in paroxysmal ventricular tachycardia not due to myocardial infarction."

Related Drugs and Biologics

1.	Cardiac Glycosides
2.	human ERBB2 protein
3.	Nifedipine (Adalat)
4.	lanatoside C
5.	Enalaprilat (Vasotec)
6.	salicylhydroxamic acid (SHAM)
7.	PTEN Phosphohydrolase (PTEN Phosphatase)
8.	Radiation-Sensitizing Agents
9.	Proteins (Proteins, Gene)
10.	Oxygen (Dioxygen)

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Administration
3.	Radioimmunotherapy
4.	Premedication
5.	Ligation

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