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Radioimmunotherapy

Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Also Known As:
Immunoradiotherapy; Immunoradiotherapies; Radioimmunotherapies
Networked: 2239 relevant articles (318 outcomes, 388 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1. Goldenberg, David M: 71 articles (02/2017 - 01/2002)
2. Press, Oliver W: 50 articles (11/2022 - 05/2002)
3. Dadachova, Ekaterina: 42 articles (12/2021 - 04/2004)
4. Boerman, Otto C: 37 articles (01/2017 - 03/2003)
5. Sharkey, Robert M: 36 articles (12/2015 - 05/2002)
6. Brechbiel, Martin W: 34 articles (12/2016 - 04/2002)
7. Oyen, Wim J G: 33 articles (01/2016 - 03/2003)
8. Morgenstern, Alfred: 32 articles (02/2020 - 11/2004)
9. Gopal, Ajay K: 31 articles (11/2022 - 05/2002)
10. Pagel, John M: 30 articles (12/2020 - 03/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Non-Hodgkin Lymphoma (Lymphosarcoma)
3. Lymphoma (Lymphomas)
4. Ovarian Neoplasms (Ovarian Cancer)
5. B-Cell Lymphoma (Lymphoma, B Cell)

Related Drugs and Biologics

1. Monoclonal Antibodies
2. Antibodies
3. Radioisotopes (Radionuclides)
4. Carcinoembryonic Antigen
5. ibritumomab tiuxetan (Zevalin)
6. Antigens
7. Rituximab (Mabthera)
8. Immunoglobulin G (IgG)
9. Paclitaxel (Taxol)
10. Yttrium-90

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. Immunotherapy
5. Stem Cell Transplantation