retinol palmitate (retinyl palmitate)

01/01/2000 - "The purpose of this study was to develop an intravenous formulation composed of retinyl palmitate (RP) for the treatment of cancer. "
06/01/1997 - "One trial showed a reduction in second primary tumors, and in particular, tumors to tobacco smoking in patients treated with retinyl palmitate. "
01/01/1983 - "This paper reports a study on the influence of excess of vitamin A palmitate on the induction and maintenance of oral tumors. "
01/01/1992 - "Topically applied retinyl palmitate reduces the incidence of cervical cancer in hamsters, and topically applied RA has a therapeutic effect on cervical dysplasia in humans. "
01/01/1990 - "Tumor incidence is reduced in those groups of experimental animals receiving 5 or 10mg Vitamin A-palmitate twice weekly for 3 months by feeding or painting during and subsequent to application of pepper extract. "

01/01/1988 - "Lung cancer chemoprevention with retinol palmitate. "
01/01/2011 - "Retinyl palmitate combined with beta carotene increased risk of lung cancer in smokers in the large CARET trial. "
08/01/2009 - "CARET was a randomized, double-blinded, placebo-controlled trial testing a daily dose of 30 mg beta-carotene + 25,000 IU retinyl palmitate for lung cancer prevention (1985-1996; active follow-up occurred through 2005). "
03/01/2000 - "The CARET study, conducted in 18,000 high-risk smokers in the US, found that a combination of beta-carotene and retinyl palmitate resulted in a 28% increase in the incidence of lung cancer. "
04/01/2003 - "We did not observe any statistically significant associations of fruit and vegetable intake with lung cancer risk among participants randomized to receive the CARET supplements (30 mg of beta-carotene and 25,000 IU of retinyl palmitate). "

09/01/1992 - "Efficacy of massive oral doses of retinyl palmitate and mango (Mangifera indica L.) consumption to correct an existing vitamin A deficiency in Senegalese children."
07/30/2014 - "Oil fortification with retinyl palmitate is intended to lower the prevalence of vitamin A deficiency in populations at risk. "
12/01/2004 - "Retinyl palmitate is taken up when it is applied topically to either metaplastically mutated rat vaginal epithelium (as a gel) or to human meta- and dysplastic bronchial epithelia (via inhalation) that have a vitamin A deficiency. "
09/28/2001 - "These data demonstrate that squamous changes induced by vitamin A deficiency can be totally reversed with topically applied retinyl palmitate."
07/01/1995 - "Vitamin A deficiency in mallards was defined as hepatic levels of retinyl palmitate < 2 micrograms/g liver. "

08/01/1998 - "Although there is currently no treatment, recent studies have indicated that 15,000 IU of vitamin A palmitate daily may slow the progression of retinitis pigmentosa; however, it is unknown whether this treatment would be effective for the inverse form of RP. "
08/01/1996 - "Patients with retinitis pigmentosa have been suggested to benefit from treatment with moderate doses of retinyl palmitate. "
06/01/2012 - "To evaluate whether a diet high in long chain ω-3 fatty acids can slow the rate of visual acuity loss among patients with retinitis pigmentosa receiving vitamin A palmitate. "
09/01/2004 - "A cohort of 208 patients with retinitis pigmentosa, aged 18 to 55 years, were randomly assigned to 1200 mg of docosahexaenoic acid plus 15 000 IU/d of vitamin A given as retinyl palmitate (DHA + A group) or control fatty acid plus 15 000 IU/d of vitamin A (control + A group) and followed up over 4 years. "
08/01/1996 - "To find out which metabolites of retinyl palmitate were formed and at which concentrations, we measured the concentrations of retinol, retinyl palmitate, retinoic acids and tocopherol in serum of patients treated with oral retinyl palmitate for retinitis pigmentosa. "

01/01/1984 - "A water-miscible preparation of retinyl palmitate was administered by intramuscular injection to well- and malnourished children with and without acute measles. "
09/01/1994 - "These assessments were part of a randomized, double-masked clinical trial of the efficacy of 210 mumol of retinol as retinyl palmitate for reducing measles-associated morbidity. "
09/01/1994 - "These results indicate that a single oral dose of 210 mumol of retinol as retinyl palmitate in oil does not enhance the immune system during measles."
01/01/1984 - "A controlled study on the effect of injected water-miscible retinyl palmitate on plasma concentrations of retinol and retinol-binding protein in children with measles in northern Nigeria."