HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

cysteinyl- prolyl- isoleucyl- glutamyl- aspartyl- arginyl- prolyl- methionyl- cysteine (1-9) disulfide

has antineoplastic activity

Also Known As:

CPIEDRPMC; Cys-Pro-Ile-Glu-Asp-Arg-Pro-Met-Cys (1-9)-disulfide; RPM peptide; RPMrel peptide

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - cysteinyl-prolyl-isoleucyl-glutamyl-aspartyl-arginyl-prolyl-methionyl-cysteine (1-9) disulfide: 3
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - cysteinyl-prolyl-isoleucyl-glutamyl-aspartyl-arginyl-prolyl-methionyl-cysteine (1-9) disulfide: 3

Experts

1.	Hong, Yun: 1 article (01/2018)
2.	Hu, Fuqiang: 1 article (01/2018)
3.	Liu, Yupeng: 1 article (01/2018)
4.	Meng, Tingting: 1 article (01/2018)
5.	Shao, Shihong: 1 article (01/2018)
6.	Yuan, Hong: 1 article (01/2018)
7.	Yuan, Ming: 1 article (01/2018)
8.	Zhu, Yun: 1 article (01/2018)
9.	Kim, Jihoon: 1 article (05/2015)
10.	Kim, Won Jong: 1 article (05/2015)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 05/10/2015 - "In this study, we exploited RPM peptide as a targeting ligand to produce a novel and efficient gene delivery system that could potentially be used to treat invasive colon cancer. " 05/10/2015 - "RPM peptide conjugated bioreducible polyethylenimine targeting invasive colon cancer." 05/10/2015 - "In order to achieve enhanced specificity to colon cancer cells, the RPM peptide was conjugated to a bioreducible gene carrier consisting of a reducible moiety of disulfide-crosslinked low molecular weight polyethylenimine, IR820 dye, and polyethylene glycol. "
2.	Neoplasms (Cancer) 09/01/2003 - "Immunohistochemical staining using FITC-conjugated RPMrel peptide also showed binding of RPMrel to colon tumor tissues from four patients. " 01/01/2018 - "The modified RPM peptide could increase the cellular internalization of CSOSA micelles in metastatic tumor cells and endothelial cells mediated by α5β1 integrin. " 05/10/2015 - "CPIEDRPMC (RPM) peptide is a peptide that specifically targets invasive colorectal cancer, which is one of the leading causes of cancer-related deaths worldwide. "
3.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2018 - "In conclusion, the RPM peptide-modified drug delivery system may provide insights into targeting the metastatic cells overexpressing the α5β1 integrin, and it has the potential to inhibit liver metastasis of colorectal cancer." 01/01/2018 - "Targeting High Expressed α5β1 Integrin in Liver Metastatic Lesions To Resist Metastasis of Colorectal Cancer by RPM Peptide-Modified Chitosan-Stearic Micelles." 05/10/2015 - "CPIEDRPMC (RPM) peptide is a peptide that specifically targets invasive colorectal cancer, which is one of the leading causes of cancer-related deaths worldwide. "
4.	Neoplasm Metastasis (Metastasis) 01/01/2018 - "In conclusion, the RPM peptide-modified drug delivery system may provide insights into targeting the metastatic cells overexpressing the α5β1 integrin, and it has the potential to inhibit liver metastasis of colorectal cancer." 01/01/2018 - "Targeting High Expressed α5β1 Integrin in Liver Metastatic Lesions To Resist Metastasis of Colorectal Cancer by RPM Peptide-Modified Chitosan-Stearic Micelles."
5.	Carcinoma (Carcinomatosis) 09/01/2003 - "Analysis of the resulting library identified a nine-amino-acid, disulfide-constrained peptide, CPIEDRPMC (RPMrel), that stained HT29 colon carcinoma cells. "

Related Drugs and Biologics

1.	Ligands
2.	Peptides (Polypeptides)
3.	Disulfides
4.	cysteinyl- prolyl- isoleucyl- glutamyl- aspartyl- arginyl- prolyl- methionyl- cysteine (1-9) disulfide
5.	Chitosan
6.	Fluorescein-5-isothiocyanate (FITC)
7.	Integrins
8.	Polyethyleneimine
9.	Polyethylene Glycols (Polyethylene Glycol)
10.	Micelles