10,17- dihydroxydocosa- 4,7,11,13,15,19- hexaenoic acid

11/24/2023 - "Phorbal-12-mysristate-13-acetate-induced inflammation is restored by protectin DX through PPARγ in human promonocytic U937 cells."
12/01/2020 - "Protectin DX (PDX) displays anti-inflammatory and potent inflammation pro-resolving actions. "
01/01/2020 - "Protectin DX attenuates IL-1β-induced inflammation via the AMPK/NF-κB pathway in chondrocytes and ameliorates osteoarthritis progression in a rat model."
10/01/2018 - "Recently, protectin DX (PDX) was also reported to attenuate inflammation and insulin resistance in several cell types. "
10/01/2018 - "Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NF-κB pathway."

10/01/2019 - "The role as well as the molecular mechanisms of protectin DX (PDX) in the prevention of hepatic insulin resistance, a hallmark of type 2 diabetes, remains unknown. "
10/01/2018 - "Recently, protectin DX (PDX) was also reported to attenuate inflammation and insulin resistance in several cell types. "
10/01/2018 - "Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NF-κB pathway."
01/01/2017 - "Recently, protectin DX (PDX) was documented to attenuate insulin resistance by stimulating IL-6 expression in skeletal muscle, thereby regulating hepatic gluconeogenesis. "
06/01/2014 - "Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis."

05/20/2018 - "Protectin DX Exhibits Protective Effects in Mouse Model of Lipopolysaccharide-Induced Acute Lung Injury."
01/01/2018 - "Protectin DX increases alveolar fluid clearance in rats with lipopolysaccharide-induced acute lung injury."
10/01/2020 - "Protectin DX ameliorates inflammation in sepsis-induced acute lung injury through mediating PPARγ/NF-κB pathway."

01/01/2018 - "Protectin DX improved alveolar fluid clearance (9.65 ± 1.60 vs. 15.85 ± 1.49, p < 0.0001) and decreased pulmonary edema and lung injury in LPS-induced lung injury in rats. "
01/01/2023 - "Protectin DX Relieve Hyperoxia-induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx."

01/01/2017 - "Protectin DX increases survival in a mouse model of sepsis by ameliorating inflammation and modulating macrophage phenotype."
01/01/2017 - "Here, we sought to evaluate whether Protectin DX (PDX, an isomer of Protecin D1), a newly identified lipid mediator, could protect mice against sepsis and explore the underling mechanism. "
10/01/2020 - "Protectin DX ameliorates inflammation in sepsis-induced acute lung injury through mediating PPARγ/NF-κB pathway."
10/01/2020 - "Previous reports have demonstrated that the newly identified lipid mediator protectin DX (PDX) could effectively attenuate multiple organ injuries in sepsis. "