Fatty Acids (Saturated Fatty Acids)

Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)

Also Known As:

Networked: 6864 relevant articles (150 outcomes, 747 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Titov, V N: 37 articles (06/2015 - 01/2001)
2.	Mozaffarian, Dariush: 23 articles (07/2015 - 02/2003)
3.	Calder, Philip C: 21 articles (09/2015 - 01/2002)
4.	Harris, William S: 20 articles (08/2015 - 11/2004)
5.	King, Irena B: 20 articles (07/2015 - 02/2003)
6.	Curi, Rui: 18 articles (10/2013 - 01/2003)
7.	Wanders, Ronald J A: 17 articles (03/2014 - 04/2002)
8.	Lopaschuk, Gary D: 17 articles (12/2013 - 09/2002)
9.	Willett, Walter C: 16 articles (12/2014 - 01/2003)
10.	Lemaitre, Rozenn N: 15 articles (07/2015 - 02/2003)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2010 - "This type of diet has several health benefits, including cardio and cancer protective effects, which are attributed to the high intake of seafood-derived n-3 (omega-3) fatty acids. " 03/01/1990 - "Some fatty acids may also be protective against cancer." 01/01/2009 - "Among diet components, some fatty acids are known to affect several stages of colon carcinogenesis, whereas others are probably helpful in preventing tumors. " 12/01/1997 - "Instead, the emphasis is on the consistency or lack of consistency of information regarding each of the above fatty acids, confounding factors that may help to reconcile discrepancies in the database, a perspective of the history of the research, and certain unique or exciting opportunities that are worthy of special attention in evaluations of the relations between specific fatty acids and cancer. " 10/01/2013 - "Recent studies describing the cancer protective effect of EPA and DHA have sparked a renewed interest in using these fatty acids for cancer prevention and treatment. "
2.	Inflammation 01/01/2013 - "ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore the relationship between serum levels of inflammation markers and MRI activity in patients with relapsing remitting MS, as well as the effect of ω-3 fatty acids on these markers. " 03/01/2011 - "Our findings indicate that ω-3 fatty acids are beneficial for protecting the premature intestine from inflammation by regulating eicosanoid- and nuclear factor-κB-related metabolite expression." 05/01/2013 - "Walnuts, rich in omega fatty acids, have been shown to improve memory, cognition and neuronal effects related to oxidative stress (OS) and inflammation (INF) in animals and human trials. " 04/01/2014 - "This study tested the hypotheses that: a) body composition, inflammation and vascular function would improve with a high fat diet (HFD) when type of fat is balanced as 1/3 SFA, 1/3 MUFA and 1/3 PUFA; and b) body composition, inflammation and vascular function would improve more when balanced HFD is supplemented with 18C fatty acids, in proportion to the degree of 18C unsaturation. " 01/01/2014 - "The present study aimed to investigate the interaction between erythrocyte phospholipid (PL) fatty acids and variants of inflammation-related genes in a Chinese population. "
3.	Insulin Resistance 02/01/2001 - "We show that transgenic expression of Cd36 in SHR ameliorates insulin resistance and lowers serum fatty acids. " 01/01/2016 - "A literature search was performed to identify prospective studies and clinical trials in humans that explored the association between dietary intake of saturated fatty acids and risk of insulin resistance and T2DM. " 12/01/2013 - "This study demonstrated that the mechanism of the different effects of medium- and long-chain fatty acids on hepatic insulin resistance involves LXRα, ChREBP and Elovl6 alternations in liver and WAT. " 07/01/2013 - "Recent animal studies have indicated that overexpression of the elongation of long-chain fatty acids family member 6 (Elovl6) gene can cause insulin resistance and β-cell dysfunction. " 08/01/2011 - "In patients with metabolic syndrome (MetS), intestinal TRL overproduction contributes to high systemic TRL levels, and recent studies suggest that systemic changes in MetS such as increases in plasma fatty acids and insulin resistance stimulate intestinal TRL production. "
4.	Cardiovascular Diseases (Cardiovascular Disease) 05/01/2006 - "(n-3) Fatty acids are unsaturated and are therefore easily subject to oxidization; however, they have several beneficial health effects, which include protection against cardiovascular diseases. " 02/01/2005 - "The high relative content of (n-3) fatty acids in traditional foods presumably provides some protection against cardiovascular diseases, type 2 diabetes and various other diseases of affluent industrialized societies. " 06/01/2014 - "In this study, we examined whether HDL from T2D patients contains elevated levels of oxidized fatty acids and whether those levels correlate with cardiovascular disease (CVD). " 09/01/2013 - "Furthermore, few studies have examined the relationship between fatty acids and the outcomes of cardiovascular disease (CVD) in Asian populations. " 01/01/2013 - "The impact of an excess of fatty acids in the diet on cardiovascular diseases has been studied and discussed both in human and animal studies. "
5.	Weight Loss (Weight Reduction) 12/01/2008 - "CLA and CLA×MUFA did not affect moisture and intramuscular fat content of dry-cured loin, weight losses during the processing, changes in the content of most fatty acids from lipid fractions and sensory traits. " 02/01/2011 - "In addition to the metabolic and cardiovascular benefits of omega-3 (n-3) fatty acids, several studies have suggested an added weight loss-enhancing benefit to this supplement. " 01/01/2008 - "Animal studies have shown that dietary short- and medium-chain fatty acids compared to long-chain fatty acids appear to promote weight loss. " 06/01/2002 - "This study assessed the contribution of genetic factors to changes in serum and adipose tissue fatty acids resulting from weight loss and followed by a subsequent year of weight maintenance. " 06/15/2014 - "Modest weight loss corrects the exaggerated myocardial channeling of dietary fatty acids and improves myocardial energy substrate metabolism and function in IGT subjects."

Related Drugs and Biologics

1.	Cholesterol
2.	Insulin (Novolin)
3.	Lipids
4.	Glucose (Dextrose)
5.	Triglycerides (Triacylglycerol)
6.	Dietary Fats (Ghee)
7.	Arachidonic Acid (Vitamin F)
8.	Carnitine (L-Carnitine)
9.	Amino Acids
10.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Ketogenic Diet
3.	Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
4.	Nutritional Support (Artificial Feeding)
5.	Enzyme Therapy