Continuous ambulatory peritoneal dialysis (
CAPD) is recognized as an effective and economical
therapy for
end-stage renal disease (
ESRD). However, the drop-out and mortality rates of this treatment remain high. The aim of the present study was to investigate the potential effects of metabolic status and personality on the prognosis of
ESRD patients receiving
CAPD. A total of 835 patients (455 men and 380 women) were enrolled in the cross-sectional survey. Analysis of variance and Spearman correlations were used to analyze variables in two groups of
ESRD patients: group L (dialysis duration < 3 years) and group H (dialysis duration ≥ 3 years). The variables included gender, age, duration of dialysis, primary
diseases, blood pressure, body mass index (BMI),
hemoglobin (Hb),
serum albumin, Subjective Global Assessment (SGA), blood
lipids, fasting
blood glucose, renal function, immunoreactive
parathyroid hormone (iPTH), serum
phosphorus and
calcium, erythrocyte sedimentation rate (ESR),
C-reactive protein (CRP), Kt/V, and Life Orientation Test-Revised (LOT-R) scores. Levels of DBP, BUN,
glucose, CRP, SBP, SGA, TG,
LDL,
creatinine, iPTH, ESR, and LOT-R scores were significantly higher in group H than in Group L, whereas Hb and Kt/V were significantly lower in group H. The dialysis duration was positively correlated with the blood pressure, SGA scores, TG,
LDL, PTH, CRP, and LOT-R scores, but negatively correlated with Kt/V. Our results suggest that
hypertension,
anemia,
hypoproteinemia, SGA, TG,
LDL, iPTH, CRP, Kt/V, and personalities are potentially important factors affecting the prognosis of ERSD patients with
CAPD.