Abstract | SUMMARY: BACKGROUND: OBJECTIVE: To compare the characteristics of so-called "metabolically healthy" obese (MHO), normal weight subjects (MHNW) and obese with insulin resistance in the United States National Health and Nutrition Examination Survey, 1999-2004 (NHANES). DESIGN, SETTING AND PARTICIPANTS:
Insulin resistance was defined by a homeostatic model assessment (HOMA) value in the upper tertile for the entire NHANES cohort. "Metabolic health" was defined as the absence of diabetes, insulin resistance, metabolic syndrome, and lipid-lowering therapy. The study evaluated the 314 MHO, 1173 MHNW and 843 insulin-resistant obese from among the 6485 non-diabetic, non-pregnant adults aged 20-79 years. MAIN OUTCOME MEASURES: Demographic, metabolic, nutrition and physical activity features. RESULTS: CONCLUSIONS: "Metabolically healthy" obese people have multiple dysmetabolic changes that may signal increased risk for coronary artery disease.
|
Authors | Peter Manu, Constantin Ionescu-Tirgoviste, James Tsang, Barbara A Napolitano, Martin L Lesser, Christoph U Correll |
Journal | Obesity research & clinical practice
(Obes Res Clin Pract)
2012 Jan-Mar
Vol. 6
Issue 1
Pg. e1-e90
ISSN: 1871-403X [Print] Netherlands |
PMID | 24331169
(Publication Type: Journal Article)
|
Copyright | © 2012 Asian Oceanian Association for the Study of Obesity . Published by Elsevier Ltd. All rights reserved. |