Abstract | CONTEXT: AIMS: In this article we examined the activity of AST, ALT, GGT, ALP, and ACP in the saliva from patients with periodontal disease, before and after periodontal treatment (experimental group - 20 gingivitis patients and 20 periodontitis patients), and in the saliva from healthy subjects (control group - 20 samples). SETTINGS AND DESIGN:
Periodontal disease was determined based on the clinical parameters (gingival index (GI), probing depth (PD), and clinical attachment loss (CAL)). Patients with periodontal disease were under conventional periodontal treatment. MATERIALS AND METHODS: The stimulated saliva of the patient was collected in a sterile test tube and analyzed using the Automatic Analyzer. RESULTS: The obtained results showed statistically significant increased activity of AST, ALT, GGT, ALP, and ACP in the saliva from patients with periodontal disease, in relation to the control group. A significant reduction in the enzyme levels was seen after conventional periodontal therapy. CONCLUSIONS: Based on these results, it can be assumed that the salivary enzymes (AST, ALT, GGT, ALP, and ACP) can be considered as biochemical markers for evaluating the diagnosis and prognosis of the functional condition of periodontal tissues in disease and health, and in the evaluation of the therapy effects in periodontal disease.
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Authors | Sarita Dabra, Kamalpreet China, Alka Kaushik |
Journal | Journal of Indian Society of Periodontology
(J Indian Soc Periodontol)
Vol. 16
Issue 3
Pg. 358-64
(Jul 2012)
ISSN: 0975-1580 [Electronic] India |
PMID | 23162329
(Publication Type: Journal Article)
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