Abstract | PURPOSE OF REVIEW: The world population is aging and a rapid increase is being seen in the very elderly (aged >80 years). Cholesterol levels in general rise with age and high cholesterol has been associated with extreme longevity. The relationship between lipids and cardiovascular events in the extreme elderly is unclear. RECENT FINDINGS: SUMMARY: The optimal cholesterol target, long-term tolerability and the specific effects of statins on other vascular-associated diseases of aging, for example arterial aneurysms, microvascular renal and cerebral disease ( dementias), remain to be determined.
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Authors | Genovefa Kolovou, Vana Kolovou, Ioannis Vasiliadis, Anthony S Wierzbicki, Dimitri P Mikhailidis |
Journal | Current opinion in cardiology
(Curr Opin Cardiol)
Vol. 26
Issue 4
Pg. 348-55
(Jul 2011)
ISSN: 1531-7080 [Electronic] United States |
PMID | 21478743
(Publication Type: Journal Article, Review)
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Chemical References |
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Lipids
- Lipoproteins
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Topics |
- Aged
- Aged, 80 and over
- Aging
- Cardiovascular Diseases
(epidemiology, prevention & control)
- Female
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
(pharmacology)
- Hyperlipidemias
(drug therapy)
- Lipid Metabolism
(drug effects, genetics)
- Lipids
(blood)
- Lipoproteins
(genetics)
- Longevity
(genetics, physiology)
- Male
- Meta-Analysis as Topic
- Polymorphism, Genetic
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