Tars

Viscous materials composed of complex, high-molecular-weight compounds derived from the distillation of petroleum or the destructive distillation of wood or coal. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Networked: 97 relevant articles (5 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Giordano, Peggy C: 2 articles (01/2022 - 12/2016)
2.	Longmore, Monica A: 2 articles (01/2022 - 12/2016)
3.	Manning, Wendy D: 2 articles (01/2022 - 12/2016)
4.	Du, Lei: 2 articles (01/2021 - 04/2019)
5.	Guo, Yingqiang: 2 articles (01/2021 - 04/2019)
6.	Kang, Deying: 2 articles (01/2021 - 04/2019)
7.	Lin, Jing: 2 articles (01/2021 - 04/2019)
8.	Wu, Zhong: 2 articles (01/2021 - 04/2019)
9.	Xiong, Jiyue: 2 articles (01/2021 - 04/2019)
10.	DeOrio, James K: 2 articles (11/2019 - 02/2016)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/1993 - "The clinical experience reported by these studies does not definitively answer the question of whether or not all or even most tars are effective in the treatment of psoriasis. " 03/01/2023 - "This review summarizes current knowledge about the chemical characterization, mechanism of action, toxicity, and clinical studies supporting the use of tars for psoriasis over the last decade. " 03/01/2023 - "Updated view of tars for psoriasis: what have we learned over the last decade?" 01/01/1976 - "An assessment of high and low temperature tars in Psoriasis." 03/01/2023 - "Large, randomized, double-blind, controlled clinical trials are necessary to promote the inclusion of tars as part of modern therapies for psoriasis."
2.	Neoplasms (Cancer) 06/17/2022 - "The expression of COPB2, DCTN4, RYK, TARS, and UIMC1 indicated association with the change of fraction of immune cells in LSCC patients; two genes, COPB2 and RYK, indicated different expression in various tumor stages of LSCC. " 02/15/2016 - "A major milestone of this effort was the publication in Cancer Research by Wynder and colleagues, which demonstrated the ability of tobacco tars to produce tumors in mice. " 02/01/2000 - "In two different animal models, tumors can be produced following exposure to DNA viruses and tars. " 01/01/2003 - "Searching additional databases beyond the Cochrane Library (which includes CCTR, NHS EED and the HTA database), MEDLINE, EMBASE and SCI, plus BIOSIS limited to meeting abstracts only, was seldom found to be effective in retrieving additional studies for inclusion in the clinical and cost-effectiveness sections of TARs (apart from reviews of cancer therapies, where a search of the ASCO database is recommended). " 01/01/2022 - "Many studies have shown that TARS are involved in tumor angiogenesis and metastasis. "
3.	Pain (Aches) 01/01/2023 - "As such, the TARS operant behavior task is an improvement over other approaches such as the mechanical conflict-avoidance system which have difficulties demonstrating development and reversal of pain behavior in a within-subject design." 05/01/2021 - "A total of 24 TARs in 16 patients with persistent or recurrent pain received integrated bone SPECT/CT using diagnostic CT settings. " 03/01/2018 - "Follow-up assessment of 12 TARs was performed 9.6 years (range, 3.3-17.8) postoperatively, including clinical examination, pain and satisfaction scales, the American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score, and the SF-36. " 10/01/2013 - "However, 18 patients (18 TARs, 14%) had a poor outcome with an AOS pain score of > 30. " 03/01/2013 - "Although TAR reduces the intensity of pain, residual pain is not infrequent even in otherwise uncomplicated TARs and soft-tissue impingement is the possible cause."
4.	Skin Diseases (Skin Disease) 01/01/1996 - "There is at least limited evidence of the activity and efficacy of various tars as well as sulfonated shale oil preparations in different frequent inflammatory skin diseases. " 07/01/1964 - "[DERMATOSES DUE TO TARS IN THE LYONS AREA. " 01/01/1996 - "Tar and sulfonated shale oil preparations are used in the treatment of a variety of inflammatory skin diseases, including psoriasis vulgaris; due to the high polycyclic aromatic hydrocarbon (PAH) content of tars, a possible relationship with cancer in humans has been postulated. "
5.	Neuralgia (Stump Neuralgia) 01/01/2023 - "Intrathecal non-viral interleukin-10 gene therapy ameliorates neuropathic pain as measured by both classical static allodynia and a novel supra-spinally mediated pain assay, the Two-Arm Rodent Somatosensory (TARS) task."

Related Drugs and Biologics

1.	Coal Tar (Estar)
2.	Interleukin-10 (Interleukin 10)
3.	Biomarkers (Surrogate Marker)
4.	Transfer RNA (tRNA)
5.	beta-cyclodextrin tetradecasulfate (CTDS)
6.	Coal (Coals)
7.	Oils
8.	Anthralin (Dithranol)
9.	Adrenal Cortex Hormones (Corticosteroids)
10.	Peruvian balsam (balsam of Peru)

Related Therapies and Procedures

1.	Therapeutics
2.	Ankle Replacement Arthroplasty
3.	Thyroidectomy
4.	Surgical Instruments (Clip)
5.	Debridement