Adrenal Cortex Hormones (Corticosteroids)

08/01/2003 - "The significant findings of 17 selected, controlled clinical trials of oral corticosteroids (OCSs) for acute exacerbations of asthma in children, compared with placebo or with other formulations of corticosteroids, can be summarized as follows: 1) OCSs are effective for the outpatient treatment of acute asthma, 2) pulmonary function tests may not be the best means of assessing the efficacy of OCSs for acute asthma, 3) early administration of OCSs for acute asthma reduces hospitalizations, 4) the critical factor for a positive outcome is early administration of the corticosteroid, and 5) OCSs are preferred for the outpatient treatment of acute asthma. "
10/01/1998 - "This study aimed to determine whether the changes in practice in the management of asthma since the early 1980s have improved standards (as assessed by higher actual/best function) and reduced the need for oral corticosteroids. "
11/01/2015 - "Combined inhaled corticosteroids and long-acting β-agonists treatments are most effective for preventing exacerbations among paediatric asthma patients. "
09/12/2015 - "Current therapies based on inhaled corticosteroids and longacting β2 agonists are effective in controlling asthma in most, but not all patients, with a few patients falling into the severe asthma category. "
01/01/2015 - "A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting β2-agonist/inhaled corticosteroids."

05/12/2009 - "Corticosteroids are highly effective in suppressing allergic inflammation, but their effects on GATA-3 are unknown. "
05/01/2001 - "While corticosteroids have proved most effective in modifying airway inflammation, the effect of inhaled corticosteroids on increased airway mucosal vascularity in asthmatics has been little studied. "
01/01/2000 - "Corticosteroids act nonspecifically, but are highly effective in controlling the inflammation rapidly. "
05/01/1998 - "Corticosteroids have proven to be most effective in modifying airway inflammation. "
01/01/2010 - "Treatment with topical and oral corticosteroids resulted in marked improvement of the corneal infiltrate and resolution of the auricular inflammation. "

01/01/2009 - "Although some studies have recently associated COPD with increased mortality, this association is questionable and the possible improved outcome could be due to the use of systemic corticosteroids in most patients with COPD."
06/01/2006 - "Corticosteroids produce a marked improvement in clinical parameters in most asthmatic patients; in contrast, corticosteroids have little effect on lung function measurements in patients with chronic obstructive pulmonary disease. "
01/01/2011 - "The clinical trials in the last 10 years revealed that fix combinations (inhaled corticosteroids/long-acting beta-2 agonist; ICS/LABA) improve lung functions and quality of life, and reduced symptoms and exacerbation rates in patients with severe and very severe COPD."
02/01/2002 - "Because very few therapies offer significant benefits to patients with COPD, and until a test is developed that will distinguish between potential steroid responders from non-responders, it is worthwhile giving all patients with COPD a trial (3-6 months) of inhaled corticosteroids to determine whether they are responsive."
03/01/1978 - "There are several theoretic reasons why corticosteroids might be useful in treating COPD; however the majority of studies have not demonstrated a positive effect, yet individual patients have attained marked improvement. "

08/01/2007 - "When used correctly, corticosteroids are a highly effective, well tolerated, cheap and generally safe treatment for active Crohn' disease. "
10/01/2001 - "Corticosteroids are highly effective in inducing clinical remission in patients with active Crohn's disease. "
02/02/1995 - "Although corticosteroids are highly effective in improving symptoms of Crohn's disease, they may have substantial toxicity. "
09/29/1994 - "Corticosteroids are the most efficacious drugs for inducing remission in active Crohn's disease, but their benefits are frequently offset by serious side effects. "
08/01/1997 - "Twenty-two patients (12 males, median age 30 years, range 18-60) with moderately active Crohn's disease were enrolled in a randomized study in which the efficacy of an elemental diet administered orally was compared to high-dose corticosteroids in achieving clinical and laboratory remission. "

02/01/2010 - "Intranasal corticosteroids are the most effective treatment for allergic rhinitis based on meta-analyses of clinical trials; however, the population in such trials is restricted and may not be representative of patients who are later treated with the medication. "
07/01/2015 - "Intranasal corticosteroids are generally considered the most effective medication class for controlling allergic rhinitis. "
03/01/2014 - "Intranasal corticosteroids are the most effective medication class for controlling allergic rhinitis (AR) symptoms. "
11/01/2013 - "Guidelines from throughout the world recommend intranasal corticosteroids (INSs) as first-line treatment for most patients with moderate to severe allergic rhinitis. "
04/01/2009 - "Intranasal corticosteroids (INSs) are the most effective treatment for allergic rhinitis (AR). "